A QTL for osteoporosis detected in an F2 population derived from White Leghorn chicken lines divergently selected for bone index

Osteoporosis, resulting from progressive loss of structural bone during the period of egg-laying in hens, is associated with an increased susceptibility to bone breakage. To study the genetic basis of bone strength, an F cross was produced from lines of hens that had been divergently selected for bone index from a commercial pedigreed White Leghorn population. Quantitative trait loci (QTL) affecting the bone index and component traits of the index (tibiotarsal and humeral strength and keel radiographic density) were mapped using phenotypic data from 372 F individuals in 32 F families. Genotypes for 136 microsatellite markers in 27 linkage groups covering ∼80% of the genome were analysed for association with phenotypes using within-family regression analyses. There was one significant QTL on chromosome 1 for bone index and the component traits of tibiotarsal and humeral breaking strength. Additive effects for tibiotarsal breaking strength represented 34% of the trait standard deviation and 7.6% of the phenotypic variance of the trait. These QTL for bone quality in poultry are directly relevant to commercial populations

Lunar material transport vehicle

The proposed vehicle, the Lunar Material Transport Vehicle (LMTV), has a mission objective of efficient lunar soil material transport. The LMTV was designed to meet a required set of performance specifications while operating under a given set of constraints. The LMTV is essentially an articulated steering, double-ended dump truck. The vehicle moves on four wheels and has two identical chassis halves. Each half consists of a chassis frame, a material bucket, two wheels with integral curvilinear synchronous motors, a fuel cell and battery arrangement, an electromechanically actuated dumping mechanism, and a powerful microprocessor. The vehicle, as designed, is capable of transporting up to 200 cu ft of material over a one mile round trip per hour. The LMTV is capable of being operated from a variety of sources. The vehicle has been designed as simply as possible with attention also given to secondary usage of components

Search for the second forbidden beta decay of 8B to the ground state of 8Be

A significant decay branch of 8B to the ground state of 8Be would extend the solar neutrino spectrum to higher energies than anticipated in the standard solar models. These high-energy neutrinos would affect current neutrino oscillation results and also would be a background to measurements of the hep process. We have measured the delayed alpha particles from the decay of 8B, with the goal of observing the two 46-keV alpha particles arising from the ground-state decay. The 8B was produced using an in-flight radioactive beam technique. It was implanted in a silicon PIN-diode detector that was capable of identifying the alpha-particles from the 8Be ground state. From this measurement we find an upper limit (at 90% confidence level) of 7.3 x 10^{-5} for the branching ratio to the ground state. In addition to describing this measurement, we present a theoretical calculation for this branching ratio.Comment: One reference corrected. Minor edits in tex

Accessing Rare Heterocycles from Alkynyl Ethers and Nitrogenous Electrophiles & The Development of Small Molecule Inhibitors Against Naegleria \u3ci\u3efowleri\u3c/i\u3e infection

https://tigerprints.clemson.edu/csrp/1002/thumbnail.jp

Silicon-on-ceramic process: Silicon sheet growth and device development for the large-area silicon sheet task of the low-cost solar array project

The technical feasibility of producing solar cell quality sheet silicon to meet the DOE 1986 cost goal of 70 cents/watt was investigated. The silicon on ceramic approach is to coat a low cost ceramic substrate with large grain polycrystalline silicon by unidirectional solidification of molten silicon. Results and accomplishments are summarized

Automated Propulsion Data Screening demonstration system

A fully-instrumented firing of a propulsion system typically generates a very large quantity of data. In the case of the Space Shuttle Main Engine (SSME), data analysis from ground tests and flights is currently a labor-intensive process. Human experts spend a great deal of time examining the large volume of sensor data generated by each engine firing. These experts look for any anomalies in the data which might indicate engine conditions warranting further investigation. The contract effort was to develop a 'first-cut' screening system for application to SSME engine firings that would identify the relatively small volume of data which is unusual or anomalous in some way. With such a system, limited and expensive human resources could focus on this small volume of unusual data for thorough analysis. The overall project objective was to develop a fully operational Automated Propulsion Data Screening (APDS) system with the capability of detecting significant trends and anomalies in transient and steady-state data. However, the effort limited screening of transient data to ground test data for throttle-down cases typical of the 3-g acceleration, and for engine throttling required to reach the maximum dynamic pressure limits imposed on the Space Shuttle. This APDS is based on neural networks designed to detect anomalies in propulsion system data that are not part of the data used for neural network training. The delivered system allows engineers to build their own screening sets for application to completed or planned firings of the SSME. ERC developers also built some generic screening sets that NASA engineers could apply immediately to their data analysis efforts

Homotopy Theory of Strong and Weak Topological Insulators

We use homotopy theory to extend the notion of strong and weak topological insulators to the non-stable regime (low numbers of occupied/empty energy bands). We show that for strong topological insulators in d spatial dimensions to be "truly d-dimensional", i.e. not realizable by stacking lower-dimensional insulators, a more restrictive definition of "strong" is required. However, this does not exclude weak topological insulators from being "truly d-dimensional", which we demonstrate by an example. Additionally, we prove some useful technical results, including the homotopy theoretic derivation of the factorization of invariants over the torus into invariants over spheres in the stable regime, as well as the rigorous justification of replacing $T^d$ by $S^d$ and $T^{d_k}\times S^{d_x}$ by $S^{d_k+d_x}$ as is common in the current literature.Comment: 11 pages, 3 figure

Dynamical Spin Response Functions for Heisenberg Ladders

We present the results of a numerical study of the 2 by L spin 1/2 Heisenberg ladder. Ground state energies and the singlet-triplet energy gaps for L = (4-14) and equal rung and leg interaction strengths were obtained in a Lanczos calculation and checked against earlier calculations by Barnes et al. (even L up to 12). A related moments technique is then employed to evaluate the dynamical spin response for L=12 and a range of rung to leg interaction strength ratios (0 - 5). We comment on two issues, the need for reorthogonalization and the rate of convergence, that affect the numerical utility of the moments treatment of response functions.Comment: Revtex, 3 figure