Experimental L-band SST satellite communications/surveillance terminal study. Volume 4 - Aircraft antenna studies

Antenna requirements for supersonic transport satellite communications syste

Predictions of the emergence of vaccine-resistant hepatitis B in The Gambia using a mathematical model

Vaccine escape variants of hepatitis B virus (HBV) have been identified world-wide. A mathematical model of HBV transmission is used to investigate the potential pattern of emergence of such variants. Attention is focused on The Gambia as a country with high quality epidemiological data, universal infant immunization and in which escape mutants after childhood infections have been observed. We predict that a variant cannot become dominant for at least 20 years from the start of vaccination, even when using a vaccine which affords no cross protection. The dominant factor responsible for this long time scale is the low rate of infectious contacts between infected and susceptible individuals (we estimate the basic reproduction number of hepatitis B in The Gambia to be 1·7). A variant strain that achieves high prevalence will also take many years to control, and it is questionable whether emergence will be identifiable by sero-surveillance until of high prevalence. The sensitivity of the model predictions to epidemiological and demographic factors is explored

Predictions of the emergence of vaccine-resistant hepatitis B in The Gambia using a mathematical model

Vaccine escape variants of hepatitis B virus (HBV) have been identified world-wide. A mathematical model of HBV transmission is used to investigate the potential pattern of emergence of such variants. Attention is focused on The Gambia as a country with high quality epidemiological data, universal infant immunization and in which escape mutants after childhood infections have been observed. We predict that a variant cannot become dominant for at least 20 years from the start of vaccination, even when using a vaccine which affords no cross protection. The dominant factor responsible for this long time scale is the low rate of infectious contacts between infected and susceptible individuals (we estimate the basic reproduction number of hepatitis B in The Gambia to be 1·7). A variant strain that achieves high prevalence will also take many years to control, and it is questionable whether emergence will be identifiable by sero-surveillance until of high prevalence. The sensitivity of the model predictions to epidemiological and demographic factors is explored

Jurisdiction and the Court of International Trade: Remarks of the Honorable Gregory W. Carman at the Conference on International Business Practice Presented by the Center for Dispute Resolution on February 27-28, 1992

The United States and the other countries of the world will continue to develop rules and laws governing their relationships in international commercial matters as the years ensue. As part of that agenda, lawyers and members of the international trading community should be familiar with the dispute resolution provisions of the United States Court of International Trade and some of the procedural and substantive problems of the Court. The Court\u27s function is to judicially review disputes under the customs and trade laws of the United States

Fire Protection Analysis of the ‘Center for the Arts’ Building\u27

In partial fulfillment of the requirements for the Degree of Masters of Science in Fire Protection Engineering, a prescriptive and performance-based analysis was performed on a building housing the Center for the Arts. The building was constructed in 1947 in California as an automobile dealership and repair shop under the provisions of the then-controlling Uniform Building Code. It subsequently underwent several occupancy changes and has since served as a beauty school, gymnastics center, and currently as a performing and visual arts center. Prescriptive analyses were conducted based primarily upon the provisions of the 2010 California Building and Fire Codes, and the 2009 edition of NFPA 101, Life Safety Code. Where required, other NFPA codes such as the 2010 editions of NFPA 13, Automatic Sprinkler Systems Handbook and NFPA 72, National Fire Alarm and Signaling Code were also referenced. The overall fire protection system was divided into subsystems and then examined. Subsystems included those involving safe egress, fire detection and notification, water-based suppression and structural fire protection. Results are provided with respect to each. The performance based analyses focused primarily upon the ability of occupants to safely escape the building after the onset of various fire events. The computer fire model, “Fire Dynamics Simulator”, was used to estimate the available safe egress times of occupants under various fire scenarios. The required times needed for safe egress were determined based upon calculation methods set forth in the Society of Fire Protection Engineering Handbook. Available and required safe egress times were compared for each of the different fire scenarios. Where deficiencies in fire protection systems were noted in the existing building layout and arrangements, recommendations for improvements are provided herein. It should be noted that these recommendations are considered a best effort and are presumed technically valid. Even so, any changes or upgrades made based upon these recommendations must still be reviewed and approved by a licensed professional fire protection engineer and the local authority having jurisdiction

Plane strain fracture toughness and mechanical properties of 5Al-2.5Sn ELI titanium at room and cryogenic temperatures Final report

Plane strain fracture toughness and mechanical properties of titanium alloy at room and cryogenic temperature