250 research outputs found

    Free Magnetic Moments in Disordered Metals

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    The screening of magnetic moments in metals, the Kondo effect, is found to be quenched with a finite probability in the presence of nonmagnetic disorder. Numerical results for a disordered electron system show that the distribution of Kondo temperatures deviates strongly from the result expected from random matrix theory. A pronounced second peak emerges for small Kondo temperatures, showing that the probability that magnetic moments remain unscreened at low temperatures increases with disorder. Analytical calculations, taking into account correlations between eigenfunction intensities yield a finite width for the distribution in the thermodynamic limit. Experimental consequences for disordered mesoscopic metals are discussed.Comment: RevTex 4.0, 4.3 pages, 4 EPS figures; typos fixed, reference added, final published versio

    Sugars and circadian regulation make major contributions to the global regulation of diurnal gene expression in Arabidopsis

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    The diurnal cycle strongly influences many plant metabolic and physiological processes. Arabidopsis thaliana rosettes were harvested six times during 12-h-light/12-h-dark treatments to investigate changes in gene expression using ATH1 arrays. Diagnostic gene sets were identified from published or in-house expression profiles of the response to light, sugar, nitrogen, and water deficit in seedlings and 4 h of darkness or illumination at ambient or compensation point [CO2]. Many sugar-responsive genes showed large diurnal expression changes, whose timing matched that of the diurnal changes of sugars. A set of circadian-regulated genes also showed large diurnal changes in expression. Comparison of published results from a free-running cycle with the diurnal changes in Columbia-0 (Col-0) and the starchless phosphoglucomutase (pgm) mutant indicated that sugars modify the expression of up to half of the clock-regulated genes. Principle component analysis identified genes that make large contributions to diurnal changes and confirmed that sugar and circadian regulation are the major inputs in Col-0 but that sugars dominate the response in pgm. Most of the changes in pgm are triggered by low sugar levels during the night rather than high levels in the light, highlighting the importance of responses to low sugar in diurnal gene regulation. We identified a set of candidate regulatory genes that show robust responses to alterations in sugar levels and change markedly during the diurnal cycle

    Chandra study of an overdensity of X-ray sources around two distant (z~0.5) clusters

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    We present results from a Chandra X-ray Observatory study of the field X-ray source populations in 4 different observations: two high-redshift (z~0.5) clusters of galaxies 3C295 and RXJ003033.2+261819; and two non-cluster fields with similar exposure time. Surprisingly, the 0.5-2 keV source surface densities (~900-1200 sources deg**-2 at a flux limit of 1.5x10**-15 erg cm**-2s**-1) measured in an ~8'x8' area surrounding each cluster exceed by a factor of ~2 the value expected on the basis of the ROSAT and Chandra logN-logS, with a significance of ~2 sigma each, or ~3.5 sigma when the 2 fields are combined (i.e. a probability to be a statistical fluctuation of <1% and <0.04%, respectively). The same analysis performed on the non-cluster fields and on the outer chips of the cluster fields does NOT show evidence of such an excess. In both cluster fields, the summed 0.5-10 keV spectrum of the detected objects is well fitted by a power-law with Gamma~1.7 similar to AGNs and shows no sign of intrinsic absorption. The few (~10 out of 35) optical identifications available to date confirm that most of them are, as expected, AGNs but the number of redshifts available is too small to allow conclusions on their nature. We discuss possible interpretations of the overdensity in terms of: a statistical variation of Cosmic Background sources; a concentration of AGNs and/or powerful starburst galaxies associated with the clusters; and g ravitational lensing of background QSO's by the galaxy clusters. All explanations are however difficult to reconcile with the large number of excess sources detected. Deeper X-ray observations and more redshifts measurements are clearly required to settle the issue.Comment: 22 LateX pages (including Tables and Figures), uses psfig.sty and emulateapj.sty. Accepted for publication in Astrophysical Journa

    Mesoscopic Kondo Effect in an Aharonov-Bohm Ring

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    An interacting quantum dot inserted in a mesoscopic ring is investigated. A variational ansatz is employed to describe the ground state of the system in the presence of the Aharonov-Bohm flux. It is shown that, for even number of electrons with the energy level spacing smaller than the Kondo temperature, the persistent current has a value similar to that of a perfect ring with the same radius. On the other hand, for a ring with odd number electrons, the persistent current is found to be strongly suppressed compared to that of an ideal ring, which implies the suppression of the Kondo-resonant transmission. Various aspects of the Kondo-assisted persistent current are discussed.Comment: 4 pages Revtex, 4 Postscript figures, final version to appear in Phys. Rev. Lett. 85, No.26 (Dec. 25, 2000

    NO synthase-generated NO acts downstream of auxin in regulating Fe-deficiency-induced root branching that enhances Fe-deficiency tolerance in tomato plants

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    In response to Fe-deficiency, various dicots increase their root branching which contributes to the enhancement of ferric-chelate reductase activity. Whether this Fe-deficiency-induced response eventually enhances the ability of the plant to tolerate Fe-deficiency or not is still unclear and evidence is also scarce about the signals triggering it. In this study, it was found that the SPAD-chlorophyll meter values of newly developed leaves of four tomato (Solanum lycocarpum) lines, namely line227/1 and Roza and their two reciprocal F1 hybrid lines, were positively correlated with their root branching under Fe-deficient conditions. It indicates that Fe-deficiency-induced root branching is critical for plant tolerance to Fe-deficiency. In another tomato line, Micro-Tom, the increased root branching in Fe-deficient plants was accompanied by the elevation of endogenous auxin and nitric oxide (NO) levels, and was suppressed either by the auxin transport inhibitors NPA and TIBA or the NO scavenger cPTIO. On the other hand, root branching in Fe-sufficient plants was induced either by the auxin analogues NAA and 2,4-D or the NO donors NONOate or SNP. Further, in Fe-deficient plants, NONOate restored the NPA-terminated root branching, but NAA did not affect the cPTIO-terminated root branching. Fe-deficiency-induced root branching was inhibited by the NO-synthase (NOS) inhibitor L-NAME, but was not affected by the nitrate reductase (NR) inhibitor NH4+, tungstate or glycine. Taking all of these findings together, a novel function and signalling pathway of Fe-deficiency-induced root branching is presented where NOS-generated rather than NR-generated NO acts downstream of auxin in regulating this Fe-deficiency-induced response, which enhances the plant tolerance to Fe-deficiency

    Kondo screening cloud effects in mesoscopic devices

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    We study how finite size effects may appear when a quantum dot in the Kondo Coulomb blockade regime is embedded into a mesoscopic device with finite wires. These finite size effects appear when the size of the mesoscopic device containing the quantum dot is of the order of the size of Kondo cloud and affect all thermodynamic and transport properties of the Kondo quantum dot. We also generalize our results to the experimentally relevant case where the wires contain several transverse modes/channels. Our results are based on perturbation theory, Fermi liquid theory and slave boson mean field theory.Comment: 19 pages, 9 figure

    Kondo Resonance in a Mesoscopic Ring Coupled to a Quantum Dot: Exact Results for the Aharonov-Bohm/Casher Effects

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    We study the persistent currents induced by both the Aharonov-Bohm and Aharonov-Casher effects in a one-dimensional mesoscopic ring coupled to a side-branch quantum dot at Kondo resonance. For privileged values of the Aharonov-Bohm-Casher fluxes, the problem can be mapped onto an integrable model, exactly solvable by a Bethe ansatz. In the case of a pure magnetic Aharonov-Bohm flux, we find that the presence of the quantum dot has no effect on the persistent current. In contrast, the Kondo resonance interferes with the spin-dependent Aharonov-Casher effect to induce a current which, in the strong-coupling limit, is independent of the number of electrons in the ring.Comment: Replaced with published version; 5 page

    Alertness and visuospatial attention in clinical depression

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    <p>Abstract</p> <p>Background</p> <p>Cognitive deficits are a substantial burden in clinical depression. The present study considered dysfunction in the right-hemispheric attention network in depression, examining alertness and visuospatial attention.</p> <p>Methods</p> <p>Three computerized visuospatial attention tests and an alertness test were administered to 16 depressive patients and 16 matched healthy controls.</p> <p>Results</p> <p>Although no significant group effect was observed, alertness predicted reduced visuospatial performance in the left hemifield. Furthermore, sad mood showed a trend towards predicting left visual field omissions.</p> <p>Conclusions</p> <p>Decreased alertness may lead to lower left hemifield visuospatial attention; this mechanism may be responsible for a spatial bias to the right side in depression, even though treatment of depression and anxiety may reduce this cognitive deficit.</p

    Superimposé: a 3D structural superposition server

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    The Superimposé webserver performs structural similarity searches with a preference towards 3D structure-based methods. Similarities can be detected between small molecules (e.g. drugs), parts of large structures (e.g. binding sites of proteins) and entire proteins. For this purpose, a number of algorithms were implemented and various databases are provided. Superimposé assists the user regarding the selection of a suitable combination of algorithm and database. After the computation on our server infrastructure, a visual assessment of the results is provided. The structure-based in silico screening for similar drug-like compounds enables the detection of scaffold-hoppers with putatively similar effects. The possibility to find similar binding sites can be of special interest in the functional analysis of proteins. The search for structurally similar proteins allows the detection of similar folds with different backbone topology. The Superimposé server is available at: http://bioinformatics.charite.de/superimpose
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