Diffractive lens fabricated with binary features less than 60 nm

We designed, fabricated, and characterized a binary diffractive lens with features less than 60nm. The lens was designed for operation in the red portion of the spectrum. Experimental measurements of lens performance agree with predictions generated by rigorous models of diffraction

TIFA, an inflammatory signaling adaptor, is tumor suppressive for liver cancer.

TIFA (TNF receptor associated factor (TRAF)-interacting protein with a Forkhead-associated (FHA) domain), also called T2BP, was first identified using a yeast two-hybrid screening. TIFA contains a FHA domain, which directly binds phosphothreonine and phosphoserine, and a consensus TRAF6-binding motif. TIFA-mediated oligomerization and poly-ubiquitinylation of TRAF6 mediates signaling downstream of the Tumor necrosis factor alpha receptor 1 (TNFaR-I) and interleukin-1/Toll-like receptor 4 (TLR4) pathways. Examining TIFA expression in hepatocellular carcinoma (HCC) tissues microarrays, we noted marked decreases TIFA reactivity in tumor versus control samples. In agreement, we found that HCC cell lines show reduced TIFA expression levels versus normal liver controls. Reconstituting TIFA expression in HCC cell lines promoted two independent apoptosis signaling pathways: the induction of p53 and cell cycle arrest, and the activation of caspase-8 and caspase-3. In contrast, the expression of a non-oligomerizing mutant of TIFA impacted cells minimally, and suppression of TIFA expression protected cells from apoptosis. Mice bearing TIFA overexpression hepatocellular xenografts develop smaller tumors versus TIFA mutant tumors; terminal deoxynucleotidyl transferase dUTP nick end labeling staining demonstrates increased cell apoptosis, and decreased proliferation, reflecting cell cycle arrest. Interestingly, p53 has a greater role in decreased proliferation than cell death, as it appeared dispensable for TIFA-induced cell killing. The findings demonstrate a novel suppressive role of TIFA in HCC progression via promotion of cell death independent of p53

Few-Body Systems Composed of Heavy Quarks

Within the past ten years many new hadrons states were observed experimentally, some of which do not fit into the conventional quark model. I will talk about the few-body systems composed of heavy quarks, including the charmonium-like states and some loosely bound states.Comment: Plenary talk at the 20th International IUPAP Conference on Few-Body Problems in Physics, to appear in Few Body Systems (2013

Renormalization of tensor-network states

We have discussed the tensor-network representation of classical statistical or interacting quantum lattice models, and given a comprehensive introduction to the numerical methods we recently proposed for studying the tensor-network states/models in two dimensions. A second renormalization scheme is introduced to take into account the environment contribution in the calculation of the partition function of classical tensor network models or the expectation values of quantum tensor network states. It improves significantly the accuracy of the coarse grained tensor renormalization group method. In the study of the quantum tensor-network states, we point out that the renormalization effect of the environment can be efficiently and accurately described by the bond vector. This, combined with the imaginary time evolution of the wavefunction, provides an accurate projection method to determine the tensor-network wavfunction. It reduces significantly the truncation error and enable a tensor-network state with a large bond dimension, which is difficult to be accessed by other methods, to be accurately determined.Comment: 18 pages 23 figures, minor changes, references adde

c-axis electrodynamics of ybco

New measurements of surface impedance in ybco show that the c-axis penetration depth and conductivity below Tc exhibit behaviour different from that observed in the planes. The c-axis penetration depth never has the linear temperature dependence seen in the ab-plane. Instead of the conductivity peak seen in the planes, the c-axis microwave conductivity falls to low values in the superconducting state, then rises slightly below 20K. These results show that c-axis transport remains incoherent below Tc, even though this is one of the least anisotropic cuprate superconductors.Comment: 4-page

Effects of doping on thermally excited quasiparticles in the high-TcT_c superconducting state

The physical properties of low energy superconducting quasiparticles in high- $T_c$ superconductors are examined using magnetic penetration depth and specific heat experimental data. We find that the low energy density of states of quasiparticles of La$_{2-x}$Sr$_x$CuO$_4$ scales with $(x-x_c)/T_c$ to the leading order approximation, where $x_c$ is the critical doping concentration below which $T_c=0$. The linear temperature term of the superfluid density is renormalized by quasiparticle interactions and the renormalization factor times the Fermi velocity is found to be doping independent.Comment: 3 pages, 3 figures, minor change to the content, fig1 is reploted, to appear in Phys Rev

Single and Many Particle Correlation Functions and Uniform Phase Bases for Strongly Correlated Systems

The need for suitable many or infinite fermion correlation functions to describe some low dimensional strongly correlated systems is discussed. This is linked to the need for a correlated basis, in which the ground state may be postive definite, and in which single particle correlations may suffice. A particular trial basis is proposed, and applied to a certain quasi-1D model. The model is a strip of the 2D square lattice wrapped around a cylinder, and is related to the ladder geometries, but with periodic instead of open boundary conditions along the edges. Analysis involves a novel mean-field approach and exact diagonalisation. The model has a paramagnetic region and a Nagaoka ferromagnetic region. The proposed basis is well suited to the model, and single particle correlations in it have power law decay for the paramagnet, where the charge motion is qualitatively hard core bosonic. The mean field also leads to a BCS-type model with single particle long range order.Comment: 23 pages, in plain tex, 12 Postscript figures included. Accepted for publication in J.Physics : Condensed Matte

The evolution of stellar metallicity gradients of the Milky Way disk from LSS-GAC main sequence turn-off stars: a two-phase disk formation history?

We use 297 042 main sequence turn-off stars selected from the LSS-GAC to determine the radial and vertical gradients of stellar metallicity of the Galactic disk in the anti-center direction. We determine ages of those turn-off stars by isochrone fitting and measure the temporal variations of metallicity gradients. Our results show that the gradients, both in the radial and vertical directions, exhibit significant spatial and temporal variations. The radial gradients yielded by stars of oldest ages (>11 Gyr) are essentially zero at all heights from the disk midplane, while those given by younger stars are always negative. The vertical gradients deduced from stars of oldest ages (>11Gyr) are negative and show only very weak variations with the Galactocentric distance in the disk plane, $R$, while those yielded by younger stars show strong variations with $R$. After being essentially flat at the earliest epochs of disk formation, the radial gradients steepen as age decreases, reaching a maxima (steepest) at age 7-8 Gyr, and then they flatten again. Similar temporal trends are also found for the vertical gradients. We infer that the assemblage of the Milky Way disk may have experienced at least two distinct phases. The earlier phase is probably related to a slow, pressure-supported collapse of gas, when the gas settles down to the disk mainly in the vertical direction. In the later phase, there are significant radial flows of gas in the disk, and the rate of gas inflow near the solar neighborhood reaches a maximum around a lookback time of 7-8 Gyr. The transition of the two phases occurs around a lookback time between 8 and 11 Gyr. The two phases may be responsible for the formation of the Milky Way thick and thin disks, respectively. And, as a consequence, we recommend that stellar age is a natural, physical criterion to distinguish thin and thick disk stars. ... (abridged)Comment: 31 pages, 17 figures, Accepted for publication in a special issue of Research in Astronomy and Astrophysics on LAMOST science