Lift Enhancement for Low-Aspect-Ratio Wings with Periodic Excitation

In an effort to enhance lift on low-aspect-ratio rectangular flat-plate wings in low-Reynolds-number post-stall flows, periodic injection of momentum is considered along the trailing edge in this numerical study. The purpose of actuation is not to reattach the flow but to change the dynamics of the wake vortices such that the resulting lift force is increased. Periodic forcing is observed to be effective in increasing lift for various aspect ratios and angles of attack, achieving a similar lift enhancement attained by steady forcing with less momentum input. Through the investigation on the influence of the actuation frequency, it is also found that there exists a frequency at which the flow locks on to a time-periodic high-lift state

Closed-Loop Control of Leading Edge Vorticity on a 3D Wing: Simulations and Low-Dimensional Models

We study model-based feedback control of the low-Reynolds-number flow over a flat plate at large angles of attack, in both two and three dimensions. Our long-term goal is to be able to manipulate the leading-edge vortices that form on low-aspect-ratio wings at high angles of attack, and that often contribute to exceptionally large lift coefficients. Intwo-dimensional simulations, we present a model-based feedback controller that uses an observer to reconstruct the entire flow field from velocity measurements at three locations, and stabilizes the flow at an angle of attack for which the natural flow state is periodic shedding. In three-dimensional simulations, we use open-loop forcing to study actuator placement, and conclude that trailing-edge actuation is more effective than leading-edge actuation in influencing the forces on the plate, as well as the wake structures. Finally, we present initial results towards extending our model-based control design to the 3D setting, and apply a selective frequency damping method to find unstable equilibrium flow fields in 3D simulations

Unsteadiness in Flow over a Flat Plate at Angle-of-Attack at Low Reynolds Numbers

Flow over an impulsively started low-aspect-ratio flat plate at angle-of-attack is investigated for a Reynolds number of 300. Numerical simulations, validated by a companion experiment, are performed to study the influence of aspect ratio, angle of attack, and planform geometry on the interaction of the leading-edge and tip vortices and resulting lift and drag coefficients. Aspect ratio is found to significantly influence the wake pattern and the force experienced by the plate. For large aspect ratio plates, leading-edge vortices evolved into hairpin vortices that eventually detached from the plate, interacting with the tip vortices in a complex manner. Separation of the leading-edge vortex is delayed to some extent by having convective transport of the spanwise vorticity as observed in flow over elliptic, semicircular, and delta-shaped planforms. The time at which lift achieves its maximum is observed to be fairly constant over different aspect ratios, angles of attack, and planform geometries during the initial transient. Preliminary results are also presented for flow over plates with steady actuation near the leading edge

Cardiovascular drugs inducing QT prolongation: facts and evidence

Acquired QT syndrome is mainly caused by the administration of drugs that prolong ventricular repolarization. On the other hand, the risk of drug-induced torsades de pointes is increased by numerous predisposing factors, such as genetic predisposition, female sex, hypokalemia and cardiac dysfunction. This adverse reaction is induced by different chemical compounds used for the treatment of a variety of pathologies, including arrhythmias. As it is known, antiarrhythmic agents and other cardiovascular drugs can prolong the QT interval, causing this adverse reaction. Of the 20 most commonly reported drugs, 10 were cardiovascular agents and these appeared in 348 of the reports (46%). Class Ia antiarrhythmic agents have frequently been linked to inducing arrhythmia, including torsades de pointes. Sotalol and amiodarone, class III antiarrhythmics, are known to prolong the QT interval by blocking IKr. Due to the severity of events caused by the therapeutic use of these drugs, in this work of revision the cardiovascular drugs that present this property and the factors and evidence will be mentioned.Fil: Taira, Carlos Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Farmacología. Cátedra de Farmacología; ArgentinaFil: Opezzo, Javier A. W.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Farmacología. Cátedra de Farmacología; ArgentinaFil: Mayer, Marcos Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Farmacología. Cátedra de Farmacología; ArgentinaFil: Höcht, Christian. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica. Departamento de Farmacología. Cátedra de Farmacología; Argentin

Unsteady Aerodynamic Forces on Small-Scale Wings: Experiments, Simulations, and Models

The goal of this work is to develop low order dynamical systems models for the unsteady lift and drag forces on small wings in various modes of flight, and to better understand the physical characteristics of unsteady laminar separation. Velocity field and body force data for a flat plate at static angle of attack and in sinusoidal pitch and plunge maneuvers are generated by 2D direct numerical simulations using an immersed boundary method at Re = 100. The lift of a sinusoidally plunging plate is found to deviate from the quasi-steady approximation at a reduced frequency of k = 0.5 over a range of Strouhal numbers. Lagrangian coherent structures illustrate formation and convection of a leading-edge vortex in sinusoidal pitch and plunge. A phenomenological ODE model with three states is shown to reproduce the lift on a flat plate at a static angle of attack above the stall angle. DNS for a 3D pitch-up maneuver of a rectangular plate at Re = 300 shows the effect of aspect ratio on vortical wake structure and lift. Wind tunnel experiments of a wing in single pitch-up and sinusoidal pitch maneuvers are compared with a dynamic model incorporating time delays and relaxation times to produce hysteresis

Interseismic coupling and refined earthquake potential on the Hayward-Calaveras fault zone

Interseismic strain accumulation and fault creep is usually estimated from GPS and alignment arrays data, which provide precise but spatially sparse measurements. Here we use interferometric synthetic aperture radar to resolve the interseismic deformation associated with the Hayward and Calaveras Faults (HF and CF) in the East San Francisco Bay Area. The large 1992–2011 SAR data set permits evaluation of short- and long-wavelength deformation larger than 2 mm/yr without alignment of the velocity field to a GPS-based model. Our time series approach in which the interferogram selection is based on the spatial coherence enables deformation mapping in vegetated areas and leads to refined estimates of along-fault surface creep rates. Creep rates vary from 0 ± 2 mm/yr on the northern CF to 14 ± 2 mm/yr on the central CF south of the HF surface junction. We estimate the long-term slip rates by inverting the long-wavelength deformation and the distribution of shallow slip due to creep by inverting the remaining velocity field. This distribution of slip reveals the locations of locked and slowly creeping patches with potential for a M6.8 ± 0.3 on the HF near San Leandro, a M6.6 ± 0.2 on the northern CF near Dublin, a M6.5 ± 0.1 on the HF south of Fremont, and a M6.2 ± 0.2 on the central CF near Morgan Hill. With cascading multisegment ruptures the HF rupturing from Berkeley to the CF junction could produce a M6.9 ± 0.1, the northern CF a M6.6 ± 0.1, the central CF a M6.9 ± 0.2 from the junction to Gilroy, and a joint rupture of the HF and central CF could produce a M7.1 ± 0.1

Feedback Control of High-Lift State for A Low-Aspect-Ratio Wing

The objective of this study is to employ feedback control to maximize time-average lift on a low-aspect-ratio wing by directly modifying the three-dimensional dynamics of the wake vortices. Flow control around such wing at post-stall angles of attack is numerically investigated at a low Reynolds number of 300 with blowing along the trailing edge. Motivated by the existence of time-periodic high-lift states under open-loop control with periodic excitation, the extremum seeking algorithm is considered for designing feedback control to lock the flow onto such high-lift states. Preliminary results are presented where the close-loop control is able to seek the optimal actuation frequency and yield high lift

Diffuse continuum gamma rays from the Galaxy

A new study of the diffuse Galactic gamma-ray continuum radiation is presented, using a cosmic-ray propagation model which includes nucleons, antiprotons, electrons, positrons, and synchrotron radiation. Our treatment of the inverse Compton (IC) scattering includes the effect of anisotropic scattering in the Galactic interstellar radiation field (ISRF) and a new evaluation of the ISRF itself. Models based on locally measured electron and nucleon spectra and synchrotron constraints are consistent with gamma-ray measurements in the 30-500 MeV range, but outside this range excesses are apparent. A harder nucleon spectrum is considered but fitting to gamma rays causes it to violate limits from positrons and antiprotons. A harder interstellar electron spectrum allows the gamma-ray spectrum to be fitted above 1 GeV as well, and this can be further improved when combined with a modified nucleon spectrum which still respects the limits imposed by antiprotons and positrons. A large electron/IC halo is proposed which reproduces well the high-latitude variation of gamma-ray emission. The halo contribution of Galactic emission to the high-latitude gamma-ray intensity is large, with implications for the study of the diffuse extragalactic component and signatures of dark matter. The constraints provided by the radio synchrotron spectral index do not allow all of the <30 MeV gamma-ray emission to be explained in terms of a steep electron spectrum unless this takes the form of a sharp upturn below 200 MeV. This leads us to prefer a source population as the origin of the excess low-energy gamma rays.Comment: Final version accepted for publication in The Astrophysical Journal (vol. 537, July 10, 2000 issue); Many Updates; 20 pages including 49 ps-figures, uses emulateapj.sty. More details can be found at http://www.gamma.mpe-garching.mpg.de/~aws/aws.htm