85 research outputs found
Hydrogen and Carbon Nanotubes from Pyrolysis-Catalysis of Waste Plastics: A Review
More than 27 million tonnes of waste plastics are generated in Europe each year representing a considerable potential resource. There has been extensive research into the production of liquid fuels and aromatic chemicals from pyrolysis-catalysis of waste plastics. However, there is less work on the production of hydrogen from waste plastics via pyrolysis coupled with catalytic steam reforming. In this paper, the different reactor designs used for hydrogen production from waste plastics are considered and the influence of different catalysts and process parameters on the yield of hydrogen from different types of waste plastics are reviewed. Waste plastics have also been investigated as a source of hydrocarbons for the generation of carbon nanotubes via the chemical vapour deposition route. The influences on the yield and quality of carbon nanotubes derived from waste plastics are reviewed in relation to the reactor designs used for production, catalyst type used for carbon nanotube growth and the influence of operational parameters
Cholinergic modulation, visual function and Alzheimer's dementia
Electrophysiological evidence at a cellular level and in vivo macroelectrode recordings converge in indicating a degree of specificity of acetylcholine action in vision. Acetylcholine (ACh) function is also thought to play a significant role in memory, learning and other cognitive processes. In this respect, ACh action is suggested to serve in both sensory and cognitive processes. The pharmacological blocking of brain muscarinic transmission has been proposed as a model of geriatric memory impairment and Alzheimer's dementia. Visual electrophysiological testing is deemed of diagnostic specificity for this disease. ACh brain neurotransmission, however, mostly contributes to the modulation of nonspecific aspects of cognition, such as arousal or attention. Alzheimer's dementia results from complex neuron alterations [which also affect muscarinic receptors among other (sub)cellular structures] rather than simply reflecting ACh impoverishment. A substantial loss of retinal ganglion cells is documented in patients with Alzheimer's disease and is consistent with electrophysiological observations. However, it is unclear to what extent the dysfunction of the visual system observable in Alzheimer's dementia is qualitatively different from that occurring spontaneously during aging. The dissimilarities between the effect of acute muscarinic blocking (e.g. by scopolamine) and dementia outnumber the similarities. Accordingly, the conventional ACh agonist-antagonist model of dementia now appears questionable, and replacement treatment with compounds enhancing ACh function proved disappointing. It is suggested that (nonspecific) ACh action becomes function-specific, as determined by the architecture of local brain circuits in which it is involved
Muscarinic blocking and synchronization of cortical narrow-band oscillatory responses to luminance stimuli
Synchronization of narrow-band cortical oscillatory response to flash stimulation and muscarinic blocking in humans
Narrow-band (ca. 100-110 Hz) oscillatory responses to luminance stimulation and muscarinic modulation of stimulus-related synchronization in man
Cortical synchronization and narrow-band oscillatory (ca. 18-45 Hz) responses to foveal pattern-reversal stimulation in man
ALTEA, a facility for the International Space Station: studying particle fluxes and cerebral functions in orbit
The ALTEA facility is aimed at studying particle fluxes and cerebral functions in orbit. A scheduled âALTEA projectâ for this facility is devoted to investigation of the possible functional impairment of the brain in the space environment due to particle radiation. An animal model for this experiment is being tested using mice irradiated in accelerators and concurrent electrophysiological investigation. Multi-disciplinary international collaboration is contributing to the development of the ALTEA facility, and to running the ALTEA experiment. The basic instrumentation is composed by 12 active particle silicon telescopes (assembled in pairs), one ElectroencephaloGrapher (EEG) and a visual stimulator, arranged in a helmet shaped device. This instrumentation is able to measure the dynamics of the functional status of the visual system, the cortical electrophysiological activity, the passage of each particle in a pre-determined energy window through the brain. These three basic instruments can be used separately or in any combination, maintaining a common time reference thus permitting several different experiments (radiation environment studies, particle physics, electrophysiology, psychophysics, etc.). ALTEA is scheduled to fly in the International Space Station (ISS) in the spring of 2003. A precursor ("ALTEINO"), based on one silicon telescope, and one EEG will be launched in the Russian module of the ISS in early 2002 and will serve as discriminating dosimeter for the particle fluences inside the ISS, and to construct a baseline for the astronaut's electrophysiological activity in orbit
Cortical synchronization, similar to 100-110 Hz oscillatory response to flash stimulation and muscarinic blocking in volunteers
Positive visual phenomena in space: A scientific case and a safety issue in space travel
AbstractMost astronauts on Apollo, Skylab, and MIR reported âflashes of lightâ occurring in different shapes and apparently moving across the visual field, in the absence of auditory, somatosensory, or olfactory abnormal percepts. A temporal correlation with heavy nuclei or protons has been documented in space and comparable phosphenes were observed by volunteers whose eyes were exposed to accelerated heavy ions at intensities below the threshold for Cerenkov visible radiation. An interaction between heavy ions and the retina was suggested. However, the biophysics of heavy ions or protons action remains undefined, the effects on photoreceptors and neuroretina have not been differentiated, and some direct action on the visual cortex never ruled out. Phosphenes are common in migraine and are known to occur also in response to the electrical stimulation of ganglion cells (in retinas without photoreceptors), optic pathways or visual cortex, with mechanisms that bypass the chemically gated channels. Intrinsic photosensitive ganglion cells exist in the retina of teleost fish and mammals. In the hypothesis of a peculiar sensitivity to subatomic particles of the visual system, phosphenes due to the activation of processes by-passing the photoreceptors would raise questions about human safety in space. The issue is particularly relevant with experiments of increasing duration being now operative in the International Space Station (ISS) and with plans of space travel outside the geomagnetic shield. Research is in progress both in the ISS and on animal models, in the framework of the NASA/ESA actions to improve the astronautsâ health in space
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