Characteristic Length Scale of Electric Transport Properties of Genomes

A tight-binding model together with a novel statistical method are used to investigate the relation between the sequence-dependent electric transport properties and the sequences of protein-coding regions of complete genomes. A correlation parameter $\Omega$ is defined to analyze the relation. For some particular propagation length $w_{max}$, the transport behaviors of the coding and non-coding sequences are very different and the correlation reaches its maximal value $\Omega_{max}$. $w_{max}$ and \omax are characteristic values for each species. The possible reason of the difference between the features of transport properties in the coding and non-coding regions is the mechanism of DNA damage repair processes together with the natural selection.Comment: 4 pages, 4 figure

A decomposition-based design optimization method with applications

A two-level design optimization metholology is described. A progress report of its application to Printed Wiring Board (PWB) assembly examples is given. The design of PWB assemblies is a complex task which is generally conducted as a sequential process. Individual PWBs are usually designed first, followed by the composition of the PWBs into an assembly. As a result, optimizing design considerations such as assembly reliability cannot be accomplished. This study showed that a two-level decomposition method can be employed to optimize for reliability at both the PWB- and the assembly-level in a coupled manner. The two-level decomposition method also resolved the mixed-integer nonlinear programming nature of the problem rather easily

Primitive roles for inhibitory interneurons in developing frog spinal cord

Understanding the neuronal networks in the mammal spinal cord is hampered by the diversity of neurons and their connections. The simpler networks in developing lower vertebrates may offer insights into basic organization. To investigate the function of spinal inhibitory interneurons in Xenopus tadpoles, paired whole-cell recordings were used. We show directly that one class of interneuron, with distinctive anatomy, produces glycinergic, negative feedback inhibition that can limit firing in motoneurons and interneurons of the central pattern generator during swimming. These same neurons also produce inhibitory gating of sensory pathways during swimming. This discovery raises the possibility that some classes of interneuron, with distinct functions later in development, may differentiate from an earlier class in which these functions are shared. Preliminary evidence suggests that these inhibitory interneurons express the transcription factor engrailed, supporting a probable homology with interneurons in developing zebrafish that also express engrailed and have very similar anatomy and functions

Distillation of mixed-state continuous-variable entanglement by photon subtraction

We present a detailed theoretical analysis for the distillation of one copy of a mixed two-mode continuous-variable entangled state using beamsplitters and coherent photon-detection techniques, including conventional on-off detectors and photon number resolving detectors. The initial Gaussian mixed-entangled states are generated by transmitting a two-mode squeezed state through a lossy bosonic channel, corresponding to the primary source of errors in current approaches to optical quantum communication. We provide explicit formulas to calculate the entanglement in terms of logarithmic negativity before and after distillation, including losses in the channel and the photon detection, and show that one-copy distillation is still possible even for losses near the typical fiber channel attenuation length. A lower bound for the transmission coefficient of the photon-subtraction beamsplitter is derived, representing the minimal value that still allows to enhance the entanglement.Comment: 13 pages, 8 figure

Nodeless superconductivity in Ca3Ir4Sn13: evidence from quasiparticle heat transport

We report resistivity $\rho$ and thermal conductivity $\kappa$ measurements on Ca$_3$Ir$_4$Sn$_{13}$ single crystals, in which superconductivity with $T_c \approx 7$ K was claimed to coexist with ferromagnetic spin-fluctuations. Among three crystals, only one crystal shows a small hump in resistivity near 20 K, which was previously attributed to the ferromagnetic spin-fluctuations. Other two crystals show the $\rho \sim T^2$ Fermi-liquid behavior at low temperature. For both single crystals with and without the resistivity anomaly, the residual linear term $\kappa_0/T$ is negligible in zero magnetic field. In low fields, $\kappa_0(H)/T$ shows a slow field dependence. These results demonstrate that the superconducting gap of Ca$_3$Ir$_4$Sn$_{13}$ is nodeless, thus rule out nodal gap caused by ferromagnetic spin-fluctuations.Comment: 5 pages, 4 figure

Simplifying the mosaic description of DNA sequences

By using the Jensen-Shannon divergence, genomic DNA can be divided into compositionally distinct domains through a standard recursive segmentation procedure. Each domain, while significantly different from its neighbours, may however share compositional similarity with one or more distant (non--neighbouring) domains. We thus obtain a coarse--grained description of the given DNA string in terms of a smaller set of distinct domain labels. This yields a minimal domain description of a given DNA sequence, significantly reducing its organizational complexity. This procedure gives a new means of evaluating genomic complexity as one examines organisms ranging from bacteria to human. The mosaic organization of DNA sequences could have originated from the insertion of fragments of one genome (the parasite) inside another (the host), and we present numerical experiments that are suggestive of this scenario.Comment: 16 pages, 1 figure, Accepted for publication in Phys. Rev.

Sunward-propagating Alfv\'enic fluctuations observed in the heliosphere

The mixture/interaction of anti-sunward-propagating Alfv\'enic fluctuations (AFs) and sunward-propagating Alfv\'enic fluctuations (SAFs) is believed to result in the decrease of the Alfv\'enicity of solar wind fluctuations with increasing heliocentric distance. However, SAFs are rarely observed at 1 au and solar wind AFs are found to be generally outward. Using the measurements from Voyager 2 and Wind, we perform a statistical survey of SAFs in the heliosphere inside 6 au. We first report two SAF events observed by Voyager 2. One is in the anti-sunward magnetic sector with a strong positive correlation between the fluctuations of magnetic field and solar wind velocity. The other one is in the sunward magnetic sector with a strong negative magnetic field-velocity correlation. Statistically, the percentage of SAFs increases gradually with heliocentric distance, from about 2.7% at 1.0 au to about 8.7% at 5.5 au. These results provide new clues for understanding the generation mechanism of SAFs