Manipulative techniques in political election campaign advertising: experience of Ukraine (Маніпулятивні прийоми у політичній передвиборчій рекламі: досвід України)

The article embraces the scope of the techniques used in manipulation of public opinion by candidates in the election process of Ukraine during the period of 2004-2012. The main focus is on the political election campaign advertising, revealing its meaning as communicative activity and as a process that mostly always is accompanied by the use of manipulative techniques. Based on the author's analysis of election campaigns and works of Ukrainian scholars, there were also determined manipulative methods and techniques that were most actively used during the last election cycles (У статті розкрито особливості використання прийомів маніпуляції суспільною свідомістю суб’єктами виборчих процесів в Україні у 2004-2012 рр. Основна увагу зосереджено на політичній передвиборчій рекламі; розкривається її зміст як комунікативної діяльності та процесу, який фактично завжди супроводжується використанням маніпулятивних технологій. На основі авторського аналізу виборчих кампаній та праць українських вчених, визначено маніпулятивні методики та прийоми, які найактивніше використовувалися під час останніх виборчих циклів

Colonization With Staphylococcus aureus in Atopic Dermatitis Patients: Attempts to Reveal the Unknown

Atopic dermatitis (AD) patients are massively colonized with Staphylococcus aureus (S. aureus) in lesional and non-lesional skin. A skin infection may become systemic if left untreated. Of interest, the incidence of multi-drug resistant S. aureus (MRSA) in AD patients is higher as compared to a healthy population, which makes treatment even more challenging. Information on the specific genetic background of S. aureus accompanying and/or causing AD flares would be of great importance in terms of possible treatment option development. In this review, we summarized the data on the prevalence of S. aureus in general in AD skin, and the prevalence of specific clones that might be associated with flares of eczema. We put our special interest in the presence and role of staphylococcal enterotoxins as important virulence factors in the epidemiology of AD-derived S. aureus. Also, we summarize the present and potentially useful future anti-staphylococcal treatment

Prospective randomized controlled pilot study on the effects of almond consumption on skin lipids and wrinkles.

ObjectiveAlmonds are a rich source of fatty acids and antioxidants, and their supplementation is known to significantly modulate serum lipids. The effects of almond on the skin's lipid barrier and the appearance of wrinkles have not yet been elucidated. The aim of this study was to investigate the effects of almond consumption on facial sebum production and wrinkles.MethodsThis was a prospective, investigator-blinded, randomized controlled trial in which subjects consumed 20% of their daily energy consumption in either almonds or a calorie-matched snack for 16 weeks. This study was completed at the UC Davis Dermatology clinic. Participants were a volunteer sample of generally healthy postmenopausal females with Fitzpatrick skin types 1 and 2. A facial photograph and image analysis system was used to obtain standardized photographs and information on wrinkle width and severity at 0, 8, and 16 weeks. Measurements of transepidermal water loss and sebum production were also completed at 0, 8, and 16 weeks.ResultsFifty healthy postmenopausal females were recruited, 31 participants were enrolled, and 28 completed the study. Under photographic analysis, the almond group had significantly decreased wrinkle severity and width compared with the control group at 16 weeks (p < .02). Changes in skin barrier function were nonsignificant, measured by the transepidermal water loss (p = .65) between the almond and control groups relative to baseline after 16 weeks. No adverse effects were reported.ConclusionOur study demonstrates that daily almond consumption may reduce wrinkle severity in postmenopausal females to potentially have natural antiaging benefits

Evaluation of Ceftaroline Activity against Heteroresistant Vancomycin-Intermediate Staphylococcus aureus and Vancomycin-Intermediate Methicillin-Resistant S. aureus Strains in an In Vitro Pharmacokinetic/Pharmacodynamic Model: Exploring the “Seesaw Effect”

A “seesaw effect” in methicillin-resistant Staphylococcus aureus (MRSA) has been demonstrated, whereby susceptibility to β-lactam antimicrobials increases as glyco- and lipopeptide susceptibility decreases. We investigated this effect by evaluating the activity of the anti-MRSA cephalosporin ceftaroline against isogenic pairs of MRSA strains with various susceptibilities to vancomycin in an in vitro pharmacokinetic/pharmacodynamic (PK/PD) model. The activities of ceftaroline at 600 mg every 12 h (q12h) (targeted free maximum concentration of drug in serum [fCmax], 15.2 μg/ml; half-life [t1/2], 2.3 h) and vancomycin at 1 g q12h (targeted fCmax, 18 μg/ml; t1/2, 6 h) were evaluated against 3 pairs of isogenic clinical strains of MRSA that developed increased MICs to vancomycin in patients while on therapy using a two-compartment hollow-fiber PK/PD model with a starting inoculum of ∼107 CFU/ml over a 96-h period. Bacterial killing and development of resistance were evaluated. Expression of penicillin-binding proteins (PBPs) 2 and 4 was evaluated by reverse transcription (RT)-PCR. The achieved pharmacokinetic parameters were 98 to 119% of the targeted values. Ceftaroline and vancomycin were bactericidal against 5/6 and 1/6 strains, respectively, at 96 h. Ceftaroline was more active against the mutant strains than the parent strains, with this difference being statistically significant for 2/3 strain pairs at 96 h. The level of PBP2 expression was 4.4× higher in the vancomycin-intermediate S. aureus (VISA) strain in 1/3 pairs. The levels of PBP2 and PBP4 expression were otherwise similar between the parent and mutant strains. These data support the seesaw hypothesis that ceftaroline, like traditional β-lactams, is more active against strains that are less susceptible to vancomycin even when the ceftaroline MICs are identical. Further research to explore these unique findings is warranted.This work was funded by an investigator-initiated grant from Forest Laboratories. M.J.R. is funded in part by NIH R21A1092055-01. We thank Abbott Laboratories for the use of the fluorescence polarization immunoassay analyzer for determination of vancomycin concentrations. We also thank Alexander Tomasz (The Rockefeller University, New York, NY) for providing strains JH-1 and JH-9. M.J.R. has received grant support, consulted for, or provided lectures for Astellas, Cubist, Forest, Pfizer, Novartis, and Rib-X. B.J.W., M.E.S., and G.W.K. have no potential conflicts of interest to declare

The Ursinus Weekly, January 14, 1957

McClure releases statement on new funds for UC • UC evaluation to be held in Feb. • Committee begins work on Campus Chest plans • Y to hear speaker Wed. • WSGA plans forum on student government • Frosh to present Show boat on January 18 • Canterbury Club hears Busler, plans Communion • Two brothers of APE announce engagements • Two Deltas engaged New Year\u27s to Ursinus women • Symons accepts state post in administrative dept. • Twelve Ursinus seniors to be included in 1957 Who\u27s who • Washington trip planned by WRC • MSGA council discusses plans for second semester • Chi Alpha to hear views on evangelism tonight • KDK drive yields 300 lbs. of clothing for Hungary • Two Sig Rho-ers pinned • Reese - Ruth engagement • Noted showman to talk at Feb. Forum • Editorial: Some comments on culture • Da Nighta afta Chrismist • Letters to the editor • Love conquereth all • American theatre: Sophistication or drama • Drexel, Delaware hand J.V. cagers first two defeats • Badminton belles begin practice • Bailey gains new post in E.C.A.C. • Heavyweight forfeit gives Fords 18-18 tie with Bruin matmen Sat. • Losing streak goes to 7 as cagers lose to Drexel, Hens • Finals schedule to be published January 21 • Herman - Eggenhofer engagement • Shelly - Frank engagementhttps://digitalcommons.ursinus.edu/weekly/1419/thumbnail.jp

The Ursinus Weekly, February 25, 1957

SGAs to sponsor forum on governments on Monday, Mar. 4 • Freshman women receive colors at program, Thurs. • Seniors to give original musical comedy, April 5, 6 • Lisle field representative to visit Ursinus tomorrow • Scholarship fund set up at U.C. by railroad company • Delta Pi man returns • Weekly to conduct vote on Wed. for best-dressed girl • UC Debating Club meets Lehigh and Rutgers of N.J. • Four charities to be supported in Campus Chest drive, March 4 to 15 • Sonnie Smith, Marge Struth voted May Queen, manager • Men\u27s government meets at advisor\u27s home • Curtain Club to present Valiant • WAA, Varsity Club hold annual dance, Friday • Curtain Club group plays for April announced • Future activities planned by U.C. Canterbury Club • Curtain Club announces name of Spring play • No classes Good Friday • Editorial: Memoranda for March 4 • Cynic • Report on the Perkiomen • Star-reaching • Who is the best-dressed woman at Ursinus? • Bears lose to Del., Rutgers; Meet division champs Wed. • U.C. to send Padula, Prutzman and Knauf to championships at G\u27burg • Prutzman stays undefeated as matmen topple cadets • Mermaids sink to Swarthmore, Wed. • Belles top G-burg; Drop first loss to Beaverhttps://digitalcommons.ursinus.edu/weekly/1422/thumbnail.jp

The Ursinus Weekly, March 4, 1957

Forum on student government scheduled for 8:00 tonight • March 15 date for annual show by students, faculty • Girls to discuss May Day on Wed. • Motion pictures viewed by Chemical Society • Chi Alpha schedules talk on integration • Curtain Club presents The Valiant, Feb. 26 • UC grad completes basic • Mary Jo Turtzo to represent UC in Glamour contest • Cub & Key Society requests outlines from junior men • 1957 Campus Chest fund drive • Annual drive begins today, closes on Friday, March 15 • YM-YW to sponsor music seminar; Begins Wednesday • YM-YW sponsor events for frosh • Local Rotarians set up scholarship to Ursinus • Frosh to present dance, The Golden nugget, Sat. • US foreign policy to be IRC program tonight • Editorial: Life for our organizations; It goes without saying • Letters to the editor • Obituary for a timid intellectual • Play review: The Valiant • He who hesitates • Ursinus five loses to Drexel, PMC; End with second worst slate, 0-16 • Belles top E. Stroudsburg; Win over William & Mary on weekend trip south • Padula emerges 4-year M. Atlantic champ; Wins second outstanding athlete award • Matmen gain first place tie with win over Drexel, 19-13 • Inside report on winless Bruinshttps://digitalcommons.ursinus.edu/weekly/1423/thumbnail.jp

The Ursinus Weekly, November 12, 1956

Freshman class chooses officers, MSGA members • MSGA discusses school activities • Famous Japanese to speak at Forum • Ursinus group attends integration conference • Editors to speak at vespers • Dean\u27s list for 1956 autumn term announced • Pre-medders hear Jeff Dean; Visit Hahnemann • Y mock balloting predicts actual results • Farese - Donia engagement • Fraternities and sororities end Fall rushing, accept new members • Our town to be presented November 15, 16 and 17 • Duke to address Chi Alpha tonight • Accounting forum to be held Thurs. • Naval officer to visit UC Tuesday • Book sales close • Editorial: The mare\u27s nest • Letters to the editor • The king and his six sons • Play review: Plum tree • Stranger at my gates • Unbeaten hockey belles stop Temple win streak, 3-0 • Gros, Woodbury, Irwin gain honors in hockey tourney • Runs by Famous, Paine, Rohm lead Bears to 20-6 romp over Aggies • Booters bow to Drexel in 5th loss, 5-3; Tie Lehigh at 2-2 • Bears win holiday; Tie Haverford, 7-7 • Phila. orchestra to present tragic cyclehttps://digitalcommons.ursinus.edu/weekly/1415/thumbnail.jp