Topological Aspects of Epistemology and Metaphysics

The aim of this paper is to show that (elementary) topology may be useful for dealing with problems of epistemology and metaphysics. More precisely, I want to show that the introduction of topological structures may elucidate the role of the spatial structures (in a broad sense) that underly logic and cognition. In some detail I’ll deal with “Cassirer’s problem” that may be characterized as an early forrunner of Goodman’s “grue-bleen” problem. On a larger scale, topology turns out to be useful in elaborating the approach of conceptual spaces that in the last twenty years or so has found quite a few applications in cognitive science, psychology, and linguistics. In particular, topology may help distinguish “natural” from “not-so-natural” concepts. This classical problem that up to now has withstood all efforts to solve (or dissolve) it by purely logical methods. Finally, in order to show that a topological perspective may also offer a fresh look on classical metaphysical problems, it is shown that Leibniz’s famous principle of the identity of indiscernibles is closely related to some well-known topological separation axioms. More precisely, the topological perspective gives rise in a natural way to some novel variations of Leibniz’s principle

Identifying phase synchronization clusters in spatially extended dynamical systems

We investigate two recently proposed multivariate time series analysis techniques that aim at detecting phase synchronization clusters in spatially extended, nonstationary systems with regard to field applications. The starting point of both techniques is a matrix whose entries are the mean phase coherence values measured between pairs of time series. The first method is a mean field approach which allows to define the strength of participation of a subsystem in a single synchronization cluster. The second method is based on an eigenvalue decomposition from which a participation index is derived that characterizes the degree of involvement of a subsystem within multiple synchronization clusters. Simulating multiple clusters within a lattice of coupled Lorenz oscillators we explore the limitations and pitfalls of both methods and demonstrate (a) that the mean field approach is relatively robust even in configurations where the single cluster assumption is not entirely fulfilled, and (b) that the eigenvalue decomposition approach correctly identifies the simulated clusters even for low coupling strengths. Using the eigenvalue decomposition approach we studied spatiotemporal synchronization clusters in long-lasting multichannel EEG recordings from epilepsy patients and obtained results that fully confirm findings from well established neurophysiological examination techniques. Multivariate time series analysis methods such as synchronization cluster analysis that account for nonlinearities in the data are expected to provide complementary information which allows to gain deeper insights into the collective dynamics of spatially extended complex systems

Theory of Concepts

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Neurons in the human amygdala encode face identity, but not gaze direction

The amygdala is important for face processing, and direction of eye gaze is one of the most socially salient facial signals. Recording from over 200 neurons in the amygdala of neurosurgical patients, we found robust encoding of the identity of neutral-expression faces, but not of their direction of gaze. Processing of gaze direction may rely on a predominantly cortical network rather than the amygdala

Carnap’s Aufbau in the Weimar Context

Quine’s classical classic interpretation succinctly characterized characterizes Carnap’s Aufbau as an attempt “to account for the external world as a logical construct of sense-data....” Consequently, “Russell” was characterized as the most important influence on the Aufbau. Those times have passed. Formulating a comprehensive and balanced interpretation of the Aufbau has turned out to be a difficult task and one that must take into account several disjointed sources. My thesis is that the core of the Aufbau rested on a problem that had haunted German philosophy since the end of the 19th century. In terms fashionable at the time, this problem may be expressed as the polarity between Leben and Geist that characterized German philosophy during the years of the Weimar Republic. At that time, many philosophers, including Cassirer, Rickert and Vaihinger, were engaged in overcoming this polarity. As I will show, Carnap’s Aufbau joined the ranks of these projects. This suggests that Lebensphilosophie and Rickert’s System der Philosophie exerted a strong influence on Carnap’s projects, an influence that is particularly conspicuous in his unpublished manuscript Vom Chaos zur Wirklichkeit. Carnap himself asserted that this manuscript could be considered “the germ of the constitution theory” of the Aufbau. Reading Chaos also reveals another strong but neglected influence on the Aufbau, namely a specific version of neutral monism put forward by the philosopher and psychologist Theodor Ziehen before World War I. Ziehen’s work contributed much to the invention of the constitutional method of quasi-analysis. -/

Ten Misconceptions from the History of Analysis and Their Debunking

The widespread idea that infinitesimals were "eliminated" by the "great triumvirate" of Cantor, Dedekind, and Weierstrass is refuted by an uninterrupted chain of work on infinitesimal-enriched number systems. The elimination claim is an oversimplification created by triumvirate followers, who tend to view the history of analysis as a pre-ordained march toward the radiant future of Weierstrassian epsilontics. In the present text, we document distortions of the history of analysis stemming from the triumvirate ideology of ontological minimalism, which identified the continuum with a single number system. Such anachronistic distortions characterize the received interpretation of Stevin, Leibniz, d'Alembert, Cauchy, and others.Comment: 46 pages, 4 figures; Foundations of Science (2012). arXiv admin note: text overlap with arXiv:1108.2885 and arXiv:1110.545

Assimilating Seizure Dynamics

Observability of a dynamical system requires an understanding of its state—the collective values of its variables. However, existing techniques are too limited to measure all but a small fraction of the physical variables and parameters of neuronal networks. We constructed models of the biophysical properties of neuronal membrane, synaptic, and microenvironment dynamics, and incorporated them into a model-based predictor-controller framework from modern control theory. We demonstrate that it is now possible to meaningfully estimate the dynamics of small neuronal networks using as few as a single measured variable. Specifically, we assimilate noisy membrane potential measurements from individual hippocampal neurons to reconstruct the dynamics of networks of these cells, their extracellular microenvironment, and the activities of different neuronal types during seizures. We use reconstruction to account for unmeasured parts of the neuronal system, relating micro-domain metabolic processes to cellular excitability, and validate the reconstruction of cellular dynamical interactions against actual measurements. Data assimilation, the fusing of measurement with computational models, has significant potential to improve the way we observe and understand brain dynamics

Neuronal Shot Noise and Brownian 1/f21/f^2 Behavior in the Local Field Potential

We demonstrate that human electrophysiological recordings of the local field potential (LFP) from intracranial electrodes, acquired from a variety of cerebral regions, show a ubiquitous $1/f^2$ scaling within the power spectrum. We develop a quantitative model that treats the generation of these fields in an analogous way to that of electronic shot noise, and use this model to specifically address the cause of this $1/f^2$ Brownian noise. The model gives way to two analytically tractable solutions, both displaying Brownian noise: 1) uncorrelated cells that display sharp initial activity, whose extracellular fields slowly decay and 2) rapidly firing, temporally correlated cells that generate UP-DOWN states