Low-speed wind tunnel investigation of the lateral-directional characterisitcs of a large-scale variable wing-sweep fighter model in the high-lift configuration

The low-speed characteristics of a large-scale model of the F-14A aircraft were studied in tests conducted in the Ames Research Center 40- by 80-Foot Wind Tunnel. The primary purpose of the present tests was the determination of lateral-directional stability levels and control effectiveness of the aircraft in its high-lift configuration. Tests were conducted at wing angles of attack between minus 2 deg and 30 deg and with sideslip angles between minus 12 deg and 12 deg. Data were taken at a Reynolds number of 8.0 million based on a wing mean aerodynamic chord of 2.24 m (7.36 ft). The model configuration was changed as required to show the effects of direct lift control (spoilers) at yaw, yaw angle with speed brake deflected, and various amounts and combinations of roll control

REDUCING SYSTEM BIAS AND SPECIFICATION ERROR IN MICRO-IMPLAN

Community/Rural/Urban Development,

Temperature-stable Gunn-diode oscillator

Oscillator consisting of Gunn diode embedded in coaxial circuit has excellent temperature stability and low fabrication costs as compared with automatic-frequency-control crystal oscillators

Flux-Confinement in Dilatonic Cosmic Strings

We study dilaton-electrodynamics in flat spacetime and exhibit a set of global cosmic string like solutions in which the magnetic flux is confined. These solutions continue to exist for a small enough dilaton mass but cease to do so above a critcal value depending on the magnetic flux. There also exist domain wall and Dirac monopole solutions. We discuss a mechanism whereby magnetic monopolesmight have been confined by dilaton cosmic strings during an epoch in the early universe during which the dilaton was massless.Comment: 8 pages, DAMTP R93/3

The small mixing angle θ13\theta_{13} and the lepton asymmetry

We present the correlation of low energy CP phases, both Dirac and Majorana, and the lepton asymmetry for the baryon asymmetry in the universe, with a certain class of Yukawa matrices that consist of two right-handed neutrinos and include one texture zero in themselves. For cases in which the amount of the lepton asymmetry $Y_L$ turns out to be proportional to $\theta_{13}^2$, we consider the relation between two types of CP phases and the relation of $Y_L$ versus the Jarlskog invariant or the amplitude of neutrinoless double beta decay as $\theta_{13}$ varies.Comment: 17 pages, 14 figures, information for figures added, version published in PR

WATER USE COMPONENTS OF A REGIONAL ACCOUNTS AND SIMULATION SYSTEM

Resource /Energy Economics and Policy,

Cystatins as calpain inhibitors: Engineered chicken cystatin- and stefin B-kininogen domain 2 hybrids support a cystatin-like mode of interaction with the catalytic subunit of μ-calpain

Within the cystatin superfamily, only kininogen domain 2 (KD2) is able to inhibit μ- and m-calpain. In an attempt to elucidate the structural requirements of cystatins for calpain inhibition, we constructed recombinant hybrids of human stefin B (an intracellular family 1 cystatin) with KD2 and Delta L110 deletion mutants of chicken cystatin-KD2 hybrids. Substitution of the N-terminal contact region of stefin B by the corresponding KD2 sequence resulted in a calpain inhibitor of K-i = 188 nM. Deletion of L110, which forms a beta -bulge in family 1 and 2 cystatins but is lacking in KD2, improved inhibition of mu -calpain 4- to 8-fold. All engineered cystatins were temporary inhibitors of calpain due to slow substrate-like cleavage of a single peptide bond corresponding to Gly9-Ala10 in chicken cystatin. Biomolecular interaction analysis revealed that, unlike calpastatin, the cystatin-type inhibitors do not bind to the calmodulin-like domain of the small subunit of calpain, and their interaction with the mu -calpain heterodimer is completely prevented by a synthetic peptide comprising subdomain B of calpastatin domain 1. Based on these results we propose that (i) cystatin-type calpain inhibitors interact with the active site of the catalytic domain of calpain in a similar cystatin-like mode as with papain and (ii) the potential for calpain inhibition is due to specific subsites within the papain-binding regions of the general cystatin fold