Light scattering detection of quantum phases of ultracold atoms in optical lattices

Ultracold atoms loaded on optical lattices can provide unprecedented experimental systems for the quantum simulations and manipulations of many quantum phases. However, so far, how to detect these quantum phases effectively remains an outstanding challenge. Here, we show that the optical Bragg scattering of cold atoms loaded on optical lattices can be used to detect many quantum phases which include not only the conventional superfluid and Mott insulating phases, but also other important phases such as various kinds of density waves (CDW), valence bond solids (VBS), CDW supersolids and VBS supersolids.Comment: 4 pages, 3 colour figures, to appear in Phys. Rev. A, Rapid Communicatio

Measurement back-action on the quantum spin-mixing dynamics of a spin-1 Bose-Einstein condensate

We consider a small F=1 spinor condensate inside an optical cavity driven by an optical probe field, and subject the output of the probe to a homodyne detection, with the goal of investigating the effect of measurement back-action on the spin dynamics of the condensate. Using the stochastic master equation approach, we show that the effect of back-action is sensitive to not only the measurement strength but also the quantum fluctuation of the spinor condensate. The same method is also used to estimate the atom numbers below which the effect of back-action becomes so prominent that extracting spin dynamics from this cavity-based detection scheme is no longer practical

Compactness of the space of causal curves

We prove that the space of causal curves between compact subsets of a separable globally hyperbolic poset is itself compact in the Vietoris topology. Although this result implies the usual result in general relativity, its proof does not require the use of geometry or differentiable structure.Comment: 15 page

10232 Report -- The Semantics of Information

The Dagstuhl Seminar 10232, "Semantics of Information" was devoted to talks by researchers in a wide range of disciplines: mathematics, computer science, systems biology, physics, and economic gam theory, all of which explored the relationship of computer science and its theory to their area

The Evolving Treatment of Diabetic Retinopathy.

Purpose: To review the current therapeutic options for the management of diabetic retinopathy (DR) and diabetic macular edema (DME) and examine the evidence for integration of laser and pharmacotherapy. Methods: A review of the PubMed database was performed using the search terms diabetic retinopathy, diabetic macular edema, neovascularization, laser photocoagulation, intravitreal injection, vascular endothelial growth factor (VEGF), vitrectomy, pars plana vitreous surgery, antiangiogenic therapy. With additional cross-referencing, this yielded 835 publications of which 301 were selected based on content and relevance. Results: Many recent studies have evaluated the pharmacological, laser and surgical therapeutic strategies for the treatment and prevention of DR and DME. Several newer diagnostic systems such as optical coherence tomography (OCT), microperimetry, and multifocal electroretinography (mfERG) are also assisting in further refinements in the staging and classification of DR and DME. Pharmacological therapies for both DR and DME include both systemic and ocular agents. Systemic agents that promote intensive glycemic control, control of dyslipidemia and antagonists of the renin-angiotensin system demonstrate beneficial effects for both DR and DME. Ocular therapies include anti-VEGF agents, corticosteroids and nonsteroidal anti-inflammatory drugs. Laser therapy, both as panretinal and focal or grid applications continue to be employed in management of DR and DME. Refinements in laser devices have yielded more tissue-sparing (subthreshold) modes in which many of the benefits of conventional continuous wave (CW) lasers can be obtained without the adverse side effects. Recent attempts to lessen the burden of anti-VEGF injections by integrating laser therapy have met with mixed results. Increasingly, vitreoretinal surgical techniques are employed for less advanced stages of DR and DME. The development and use of smaller gauge instrumentation and advanced anesthesia agents have been associated with a trend toward earlier surgical intervention for diabetic retinopathy. Several novel drug delivery strategies are currently being examined with the goal of decreasing the therapeutic burden of monthly intravitreal injections. These fall into one of the five categories: non-biodegradable polymeric drug delivery systems, biodegradable polymeric drug delivery systems, nanoparticle-based drug delivery systems, ocular injection devices and with sustained release refillable devices. At present, there remains no one single strategy for the management of the particular stages of DR and DME as there are many options that have not been rigorously tested through large, randomized, controlled clinical trials. Conclusion: Pharmacotherapy, both ocular and systemic, will be the primary mode of intervention in the management of DR and DME in many cases when cost and treatment burden are less constrained. Conventional laser therapy has become a secondary intervention in these instances, but remains a first-line option when cost and treatment burden are more constrained. Results with subthreshold laser appear promising but will require more rigorous study to establish its role as adjunctive therapy. Evidence to support an optimal integration of the various treatment options is lacking. Central to the widespread adoption of any therapeutic regimen for DR and DME is substantiation of safety, efficacy, and cost-effectiveness by a body of sound clinical trials