8,274 research outputs found
Pairing effect on the giant dipole resonance width at low temperature
The width of the giant dipole resonance (GDR) at finite temperature T in
Sn-120 is calculated within the Phonon Damping Model including the neutron
thermal pairing gap determined from the modified BCS theory. It is shown that
the effect of thermal pairing causes a smaller GDR width at T below 2 MeV as
compared to the one obtained neglecting pairing. This improves significantly
the agreement between theory and experiment including the most recent data
point at T = 1 MeV.Comment: 8 pages, 5 figures to be published in Physical Review
Phases of lattice hard core bosons in a periodic superlattice
We study by Quantum Monte Carlo simulations the phase diagram of lattice hard
core bosons with nearest-neighbour repulsive interactions, in the presence of a
super-lattice of adsorption sites. For a moderate adsorption strength, the
system forms crystal phases registered with the adsorption lattice; a
"supersolid" phase exists, on both the vacancy and interstitial sides, whereas
at commensuration the superfluid density vanishes. The possible relevance of
these results to experiments on He films adsorbed on graphite is discussed.Comment: 5 pages, 5 figure
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Genome-wide Integrative Analysis of Zika-Virus-Infected Neuronal Stem Cells Reveals Roles for MicroRNAs in Cell Cycle and Stemness.
Zika virus (ZIKV) infection is implicated in severe fetal developmental disorders, including microcephaly. MicroRNAs (miRNAs) post-transcriptionally regulate numerous processes associated with viral infection and neurodegeneration, but their contribution to ZIKV pathogenesis is unclear. We analyzed the mRNA and miRNA transcriptomes of human neuronal stem cells (hNSCs) during infection with ZIKV MR766 and Paraiba strains. Integration of the miRNA and mRNA expression data into regulatory interaction networks showed that ZIKV infection resulted in miRNA-mediated repression of genes regulating the cell cycle, stem cell maintenance, and neurogenesis. Bioinformatics analysis of Argonaute-bound RNAs in ZIKV-infected hNSCs identified a number of miRNAs with predicted involvement in microcephaly, including miR-124-3p, which dysregulates NSC maintenance through repression of the transferrin receptor (TFRC). Consistent with this, ZIKV infection upregulated miR-124-3p and downregulated TFRC mRNA in ZIKV-infected hNSCs and mouse brain tissue. These data provide insights into the roles of miRNAs in ZIKV pathogenesis, particularly the microcephaly phenotype
Analysis of parametric biological models with non-linear dynamics
In this paper we present recent results on parametric analysis of biological
models. The underlying method is based on the algorithms for computing
trajectory sets of hybrid systems with polynomial dynamics. The method is then
applied to two case studies of biological systems: one is a cardiac cell model
for studying the conditions for cardiac abnormalities, and the second is a
model of insect nest-site choice.Comment: In Proceedings HSB 2012, arXiv:1208.315
The effects of earnings management on information asymmetry and stock price synchronicity
In this study, we test whether earnings management has a positive impact on information asymmetry as well as whether earnings management has a negative impact on stock return synchronicity to investigate how discretionary accrual earnings management affects the imbalance of information and the co-movement of stock prices in Vietnam. We utilise the Pooled OLS (OLS), Random Effects (RE), Fixed Effects (FE), and System GMM models to evaluate our dataset collected from 356 non-financial companies listed on the Hochiminh City Stock Exchange (HOSE) spanning from 2012 to 2021. We find that in Vietnamese market earnings manipulations through accrual based falsify the market and cause information asymmetry leading to adverse effects on market liquidity and stock price synchronicity. Additionally, our findings exhibit greater co-movements between stock prices and earnings management at the larger firms with long incorporation history and are audited by Big Four Audit firms due to their credibility. These findings are particularly useful for foreign investors in making investment decisions as we found that their influences on earnings management in Vietnamese market is limited
Stock Market and Inequality Distributions – Evidence from the BRICS and G7 Countries
By examining the effects of three stock market indicators (market accessibility, efficiency, and stability) on income and wealth inequality in the BRICS and G7 countries, this study enriches lacking literature on income and wealth inequality, particularly for the BRICS countries. We apply the Autoregressive Distributed Lag–Mixed Data Sampling (ADL-MIDAS) model. We find that only enhancements in market stability reduce income inequality in the BRICS and G7 countries. Additionally, we find that while expansions of market accessibility contribute to narrowing wealth inequality, improvements in market stability widen the wealth disparity in the BRICS countries. Limited effects of the stock market indicators on wealth distribution are observed in the G7 countries
Tuning Electrical Conductivity of CNT-PDMS Nanocomposites for Flexible Electronic Applications
This paper presents a study into the electrical conductivity of multi-wall carbon nanotube-polydimethylsiloxane (MWNT-PDMS) nanocomposite and their dependence on the filler concentration. It is observed that the electrical conductivity of the composites can be tailored by altering the filler concentration. Accordingly, the nanocomposites with filler weight ratio ranging from 1% to 8% were prepared and tested. Finally, the significance of results presented here for flexible pressure sensors and stretchable interconnects for electronic skin applications have been discussed
Predicting mitochondrial dynamic behavior in genetically defined neurodegenerative diseases
Mitochondrial dynamics encompass mitochondrial fusion, fission, and movement. Mitochondrial fission and fusion are seemingly ubiquitous, whereas mitochondrial movement is especially important for organelle transport through neuronal axons. Here, we review the roles of different mitochondrial dynamic processes in mitochondrial quantity and quality control, emphasizing their impact on the neurological system in Charcot-Marie-Tooth disease type 2A, amyotrophic lateral sclerosis, Friedrich\u27s ataxia, dominant optic atrophy, and Alzheimer\u27s, Huntington\u27s, and Parkinson\u27s diseases. In addition to mechanisms and concepts, we explore in detail different technical approaches for measuring mitochondrial dynamic dysfunction in vitro, describe how results from tissue culture studies may be applied to a better understanding of mitochondrial dysdynamism in human neurodegenerative diseases, and suggest how this experimental platform can be used to evaluate candidate therapeutics in different diseases or in individual patients sharing the same clinical diagnosis
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