526 research outputs found
Antiferromagnetic Critical Fluctuations in BaFeAs
Magnetic correlations near the magneto-structural phase transition in the
bilayer iron pnictide parent compound, BaFeAs, are measured. In close
proximity to the antiferromagnetic phase transition in BaFeAs, a
crossover to three dimensional critical behavior is anticipated and has been
preliminarily observed. Here we report complementary measurements of
two-dimensional magnetic fluctuations over a broad temperature range about
T. The potential role of two-dimensional critical fluctuations in the
magnetic phase behavior of BaFeAs and their evolution near the
anticipated crossover to three dimensional critical behavior and long-range
order are discussed.Comment: 6 pages, 4 figures; Accepted for publication in Physical Review
Electron tunneling between two electrodes mediated by a molecular wire containing a redox center
We derive an explicit expression for the quantum conductivity of a molecular
wire containing a redox center, which is embedded in an electrochemical
environment. The redox center interacts with the solvent, and the average over
the solvent configurations is performed numerically. Explicit calculations have
been performed for a chain of three atoms. When the redox center interacts
strongly with neighboring electronic levels, the current-potential curves show
interesting features like rectification, current plateaus and negative
differential resistance. Electronic spectroscopy of intermediate states can be
performed at constant small bias by varying the electrochemical potential of
the wire
Superconductivity induced by Ni doping in BaFeAs
A series of 122 phase BaFeNiAs ( = 0, 0.055, 0.096, 0.18,
0.23) single crystals were grown by self flux method and a dome-like Ni doping
dependence of superconducting transition temperature is discovered. The
transition temperature reaches a maximum of 20.5 K at = 0.096,
and it drops to below 4 K as 0.23. The negative thermopower in the
normal state indicates that electron-like charge carrier indeed dominates in
this system. This Ni-doped system provides another example of superconductivity
induced by electron doping in the 122 phase.Comment: 7 pages, 5 figures, revised version, added EDX result, accepted for
special issue of NJ
Surface Chemical Composition of Size-Fractionated Urban Walkway Aerosols Determined by X-Ray Photoelectron Spectroscopy
Superconductivity induced by cobalt doping in iron-based oxyarsenides
Chemical doping has recently become a very important strategy to induce
superconductivity especially in complex compounds. Distinguished examples
include Ba-doped LaCuO (the first high temperature superconductor),
K-doped BaBiO, K-doped C and NaCoOHO. The
most recent example is F-doped LaFeAsO, which leads to a new class of high
temperature superconductors. One notes that all the above dopants are
non-magnetic, because magnetic atoms generally break superconducting Cooper
pairs. In addition, the doping site was out of the (super)conducting structural
unit (layer or framework). Here we report that superconductivity was realized
by doping magnetic element cobalt into the (super)conducting-active
FeAs layers in LaFeCoAsO. At surprisingly small Co-doping
level of =0.025, the antiferromagnetic spin-density-wave transition in the
parent compound is completely suppressed, and superconductivity with
10 K emerges. With increasing Co content, shows a maximum of 13 K at
, and then drops to below 2 K at =0.15. This result suggests
essential differences between previous cuprate superconductor and the present
iron-based arsenide one.Comment: 4 pages, 4 figure
Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model
Intraperitoneal (IP) chemotherapy is more effective than systemic chemotherapy for treating advanced ovarian cancer, but is typically associated with severe complications due to high dose, frequent administration schedule, and use of non-biocompatible excipients/delivery vehicles. Here, we developed paclitaxel (PTX)-loaded microspheres composed of di-block copolymers of poly(ethylene glycol) and poly(sebacic acid) (PEG-PSA) for safe and sustained IP chemotherapy. PEG-PSA microspheres provided efficient loading (∼13 % w/w) and prolonged release (∼13 days) of PTX. In a murine ovarian cancer model, a single dose of IP PTX/PEG-PSA particles effectively suppressed tumor growth for more than 40 days and extended the median survival time to 75 days compared to treatments with Taxol® (47 days) or IP placebo particles (34 days). IP PTX/PEG-PSA was well tolerated with only minimal to mild inflammation. Our findings support PTX/PEG-PSA microspheres as a promising drug delivery platform for IP therapy of ovarian cancer and potentially other metastatic peritoneal cancers
Abi1 gene silencing by short hairpin RNA impairs Bcr-Abl-induced cell adhesion and migration in vitro and leukemogenesis in vivo
Abl interactor (Abi) 1 was first identified as the downstream target of Abl tyrosine kinases and was found to be dysregulated in leukemic cells expressing oncogenic Bcr-Abl and v-Abl. Although the accumulating evidence supports a role of Abi1 in actin cytoskeleton remodeling and growth factor/receptor signaling, it is not clear how it contributes to Bcr-Abl-induced leukemogenesis. We show here that Abi1 gene silencing by short hairpin RNA attenuated the Bcr-Abl-induced abnormal actin remodeling, membrane-type 1 metalloproteinase clustering and inhibited cell adhesion and migration on fibronectin-coated surfaces. Although the knock down of Abi1 expression did not affect growth factor-independent growth of Bcr-Abl-transformed Ba/F3 cells in vitro, it impeded competitive expansion of these cells in non obese diabetic (NOD)/ severe combined immuno-deficiency (SCID) mice. Remarkably, the knock down of Abi1 expression in Bcr-Abl-transformed Ba/F3 cells impaired the leukemogenic potential of these cells in NOD/SCID mice. Abi1 contributes to Bcr-Abl-induced leukemogenesis in part through Src family kinases, as the knock down of Abi1 expression attenuates Bcr-Abl-stimulated activation of Lyn. Together, these data provide for the first time the direct evidence that supports a critical role of Abi1 pathway in the pathogenesis of Bcr-Abl-induced leukemia
\psi(2S) Decays into \J plus Two Photons
Using \gamma \gamma J/\psi, J/\psi \ra e^+ e^- and events
from a sample of \psip decays collected with the BESII
detector, the branching fractions for \psip\ra \pi^0\J, \eta\J, and
\psi(2S)\ar\gamma\chi_{c1},\gamma\chi_{c2}\ar\gamma\gamma\jpsi are measured
to be B(\psip\ra \pi^0\J) = (1.43\pm0.14\pm0.13)\times 10^{-3}, B(\psip\ra
\eta\J) = (2.98\pm0.09\pm0.23)%,
B(\psi(2S)\ar\gamma\chi_{c1}\ar\gamma\gamma\jpsi) = (2.81\pm0.05\pm 0.23)%,
and B(\psi(2S)\ar\gamma\chi_{c2}\ar\gamma\gamma\jpsi) = (1.62\pm0.04\pm
0.12)%.Comment: 7 pages, 6 figures. submitted to Phys. Rev.
Measurement of the branching fractions of psi(2S) -> 3(pi+pi-) and J/psi -> 2(pi+pi-)
Using data samples collected at sqrt(s) = 3.686GeV and 3.650GeV by the BESII
detector at the BEPC, the branching fraction of psi(2S) -> 3(pi+pi-) is
measured to be [4.83 +- 0.38(stat) +- 0.69(syst)] x 10^-4, and the relative
branching fraction of J/psi -> 2(pi+pi-) to that of J/psi -> mu+mu- is measured
to be [5.86 +- 0.19(stat) +- 0.39(syst)]% via psi(2S) -> (pi+pi-)J/psi, J/psi
-> 2(pi+pi-). The electromagnetic form factor of 3(pi+pi-) is determined to be
0.21 +- 0.02 and 0.20 +- 0.01 at sqrt(s) = 3.686GeV and 3.650GeV, respectively.Comment: 17pages, 7 figures, submitted to Phys. Rev.
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