Sacred Vows, Public Purposes: Religion, the Marriage Movement and Marriage Policy

Focuses on the ways in which public policy is promoting marriage, church-state cooperation on behalf of marriage, and the likelihood that these public policies will meet with success. Looks at the central moral issues raised by marriage policy

FOCUSED ON THEIR FAMILIES: Religion, Parenting, & Child Well-being

In recent years, scholars have drawn attention to religious commitments to patriarchy and parental authority to argue that religion—especially conservative Protestantism—fosters an authoritarian approach to parenting. Indeed, using data from the National Survey of Families and Households (NSFH), this study does find that religious attendance and theological conservatism are associated with higher levels of corporal punishment among parents—potentially an indicator of authoritarian parenting. But religious attendance and theological conservatism are also associated with lower levels of parental yelling and with higher levels of praising and hugging among parents, which are indicators of an authoritative style of parenting. Moreover, data from the Survey of Adults and Youth (SAY) indicate that religious attendance and orthodoxy are generally associated with greater parental investments in childrearing, more intergenerational closure, and more social control. In other words, conservative Protestants, Orthodox Jews, traditional Catholics, and other parents who regularly attend religious services are more likely than other parents to adopt an authoritative style of parenting that is beneficial to children.

Bonding Alone: Familism, Religion, and Secular Civic Participation

This study examines the influence of familism, religion, and their interaction on participation in secular voluntary associations. We develop an insularity theory to explain how familism and religion encourage Americans to avoid secular civic participation. Using data from the first wave of the National Survey of Families and Households, this study finds that familism reduces participation in secular organizations. Moreover, religion moderates the effect of familism: specifically, religious involvement tends to increase the negative effect of familism on secular civic participation. Although religious involvement in and of itself fosters secular civic participation, strong familism tends to dampen positive impacts of religious involvement. For familistic individuals, religious congregations appear to reinforce their insularity within their immediate social circle and family

Bendito Amor: Religion and Relationships among Married and Unmarried Latinos in Urban America

The family arrangements of Latinos in the U.S. are increasingly diverse, with growing numbers of Latino children living in households headed by married and unmarried parents. Latinos also tend to be more religious than the population at large. Yet no research has examined the associations between religion and relationship quality among married and unmarried Latinos. Using data from the Fragile Families and Child Wellbeing Study, which focuses on new parents in urban America, we find that the religious attendance of Latino fathers promotes higher-quality relationships among both fathers and mothers; by contrast, the effect of maternal attendance on relationship quality is insignificant or negative.

The School to Family Pipeline: What Do Religious, Private, and Public Schooling Have to Do with Family Formation?

Private religious schools are widely seen as value-laden communities that mold the character of their students. Thus, we expect adults who attended religious schools as children to demonstrate more favorable family outcomes related to stable marriages and childbearing. We further expect Protestant schooling to have a more powerful effect on marital outcomes than Catholic schooling, given the heavier focus of Protestantism on marriage. Finally, we expect stronger positive associations between religious schooling and marital outcomes for adults who grew up in difficult circumstances compared to adults who grew up in advantaged circumstances. We test these hypotheses using survey data from the Understanding America Study. Our three outcome variables are ever marrying and never divorcing, ever divorcing, and conceiving a child out-of-wedlock. Most of the results confirm our hypotheses. Protestant schooling is associated with more positive marital outcomes across all three measures. Catholic schooling is significantly correlated with a lower likelihood of having a child outside of marriage. The associations between religious schooling and desirable marriage outcomes are strongest for adults who grew up poor and for those raised in intact families

Making the Grade: Family Structure and Children’s Educational Participation in Colombia, Egypt, India, Kenya, Nigeria, Peru & Uruguay

Research in the U.S. and much of the developed world suggests that children in intact, twoparent households typically do better on educational outcomes than do children in singleparent and step-family households. While studies in the developed world generally indicate that family structure influences educational outcomes, less is known about whether children living with their two biological parents in the developing world have better educational outcomes, all things being equal, than children in step- or single-parent families, or children living in households without a biological parent. This is an important gap in the literature because step- and single-parent families are becoming more common in much of the developing world. Using data drawn from Demographic and Health Surveys in six countries (Colombia, Egypt, India, Kenya, Nigeria, & Peru) and from the Continuous Household Survey in Uruguay, we find that secondary-school-age children are more likely to participate in schooling if they live with at least one biological parent. Moreover, children in Colombia and Uruguay are also more likely to be enrolled in school if they live with two parents

Religious Identity, Religious Attendance, and Parental Control

Using a national sample of adolescents aged 10–18 years and their parents (N = 5,117), this article examines whether parental religious identity and religious participation are associated with the ways in which parents control their children. We hypothesize that both religious orthodoxy and weekly religious attendance are related to heightened levels of three elements of parental control: monitoring activities, normative regulations, and network closure. Results indicate that an orthodox religious identity for Catholic and Protestant parents and higher levels of religious attendance for parents as a whole are associated with increases in monitoring activities and normative regulations of American adolescents

Ocean acidification alters morphology of all otolith types in Clark’s anemonefish (Amphiprion clarkii)

Ocean acidification, the ongoing decline of surface ocean pH and [CO ${}_{3}^{2-}$ 3 2 − ] due to absorption of surplus atmospheric CO2, has far-reaching consequences for marine biota, especially calcifiers. Among these are teleost fishes, which internally calcify otoliths, critical elements of the inner ear and vestibular system. There is evidence in the literature that ocean acidification increases otolith size and alters shape, perhaps impacting otic mechanics and thus sensory perception. Here, larval Clark’s anemonefish, Amphiprion clarkii (Bennett, 1830), were reared in various seawater pCO2/pH treatments analogous to future ocean scenarios. At the onset of metamorphosis, all otoliths were removed from each individual fish and analyzed for treatment effects on morphometrics including area, perimeter, and circularity; scanning electron microscopy was used to screen for evidence of treatment effects on lateral development, surface roughness, and vaterite replacement. The results corroborate those of other experiments with other taxa that observed otolith growth with elevated pCO2, and provide evidence that lateral development and surface roughness increased as well. Both sagittae exhibited increasing area, perimeter, lateral development, and roughness; left lapilli exhibited increasing area and perimeter while right lapilli exhibited increasing lateral development and roughness; and left asterisci exhibited increasing perimeter, roughness, and ellipticity with increasing pCO2. Right lapilli and left asterisci were only impacted by the most extreme pCO2 treatment, suggesting they are resilient to any conditions short of aragonite undersaturation, while all other impacted otoliths responded to lower concentrations. Finally, fish settlement competency at 10 dph was dramatically reduced, and fish standard length marginally reduced with increasing pCO2. Increasing abnormality and asymmetry of otoliths may impact inner ear function by altering otolith-maculae interactions

The National COVID Cohort Collaborative (N3C): Rationale, design, infrastructure, and deployment.

OBJECTIVE: Coronavirus disease 2019 (COVID-19) poses societal challenges that require expeditious data and knowledge sharing. Though organizational clinical data are abundant, these are largely inaccessible to outside researchers. Statistical, machine learning, and causal analyses are most successful with large-scale data beyond what is available in any given organization. Here, we introduce the National COVID Cohort Collaborative (N3C), an open science community focused on analyzing patient-level data from many centers. MATERIALS AND METHODS: The Clinical and Translational Science Award Program and scientific community created N3C to overcome technical, regulatory, policy, and governance barriers to sharing and harmonizing individual-level clinical data. We developed solutions to extract, aggregate, and harmonize data across organizations and data models, and created a secure data enclave to enable efficient, transparent, and reproducible collaborative analytics. RESULTS: Organized in inclusive workstreams, we created legal agreements and governance for organizations and researchers; data extraction scripts to identify and ingest positive, negative, and possible COVID-19 cases; a data quality assurance and harmonization pipeline to create a single harmonized dataset; population of the secure data enclave with data, machine learning, and statistical analytics tools; dissemination mechanisms; and a synthetic data pilot to democratize data access. CONCLUSIONS: The N3C has demonstrated that a multisite collaborative learning health network can overcome barriers to rapidly build a scalable infrastructure incorporating multiorganizational clinical data for COVID-19 analytics. We expect this effort to save lives by enabling rapid collaboration among clinicians, researchers, and data scientists to identify treatments and specialized care and thereby reduce the immediate and long-term impacts of COVID-19

Whole-genome sequencing reveals host factors underlying critical COVID-19

Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2–4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes—including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)—in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease