Clinical course and treatment of patients with differentiated

Celem pracy była analiza obrazu klinicznego i sposobu leczenia chorych na zróżnicowane raki tarczycy (ZRT) rozpoznane w Polsce w 1995 roku. Materiał obejmował grupę 478 chorych na raka tarczycy. Byli oni konsultowani, diagnozowani lub leczeni w Centrum Onkologii - Instytucie im. M Skłodowskiej- Curie w Gliwicach. Grupa ta stanowi 57,7% wszystkich raków tarczycy rozpoznanych w Polsce w tym roku. Do dalszej szczegółowej analizy włączono jedynie 352 chorych na zróżnicowane raki tarczycy leczonych operacyjnie. 292 osoby (60%) było dodatkowo leczone jodem radioaktywnym. Wszyscy chorzy otrzymywali supresyjne leczenie tyroksyną. W czasie obserwacji wznowa miejscowa wystąpiła u 37 chorych (8,6%). Odsetek 10-letnich przeżyć całkowitych wynosił 96,4%, a bezobjawowych 68%. Korzystając z faktu opublikowania przez Holtzera i wsp. danych dotyczących obrazu raka tarczycy rozpoznanego w Niemczech w 1996 roku w pracy dokonano dodatkowo porównania obu populacji. Przedstawiona analiza pozwala wnioskować, że postępowanie lecznicze w zróżnicowanych rakach tarczycy pozwala na uzyskanie satysfakcjonujących, dobrych wyników leczenia, a obraz kliniczny choroby i metody terapeutyczne są w Polsce i w Niemczech podobne.The aim of the study was to analyze the clinical course and therapy in patients with differentiated thyroid carcinoma (DTC) diagnosed in Poland within the year 1995. The group of 478 patients with thyroid cancer (57.7% of all thyroid cancer cases diagnosed this year in Poland) was analyzed. Patients were diagnosed or treated in Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch. Detailed analysis was performed in 352 patients with DTC who were treated by surgery. 292 patients (60%) received adjuvant radioiodine therapy. Hormonal (L-thyroxine) treatment was administered to all patients. In 37 patients (8.6%) local recurrence was observed. 10-year overall survival was 96.4% and disease-free survival was respectively 68%. The comparison of Polish data to analysis in German population published by Holtzer et al. (Cancer, 2000) was also performed in this study. We conclude that DTC therapy, currently recommended in our country, gives satisfactory results and that clinical outcome and therapeutic methods are similar both in Poland and Germany

Few-nucleon system dynamics studied via deuteron-deuteron collisions at 160 MeV

Four nucleon scattering at intermediate energies provides unique opportunities to study effects of the two key ingredients of the nuclear dynamics, the nucleon-nucleon P-wave (NNP-wave) and the three-nucleon force (3NF). This is possible only with systematic and precise data, in conjunction with exact theoretical calculations. Using the BINA detector at KVI Groningen, the Netherlands, a rich set of differential cross section of the 2H(d, dp)n breakup reaction at 160 MeV deuteron beam energy has been measured. Besides the three-body breakup, also cross sections of the 2H(d, 3He)n proton transfer reaction have been obtained. The data are compared to the recent calculations for the three-cluster breakup

Current stage of studies of the star configurations at intermediate energies with the use of the BINA detector

The Space Star Anomaly in proton-deuteron breakup cross-section occurs at energies of about 10 MeV. Data for higher energies are sparse. Therefore, a systematic scan over star configurations in the range of intermediate energies between 50 and 100 MeV/nucleon is carried out on the basis of data collected with the large acceptance BINA detector. The preliminary cross section results for forward star configurations at 80 MeV/nucleon slightly surpass the theoretical calculations, but the systematic uncertainties are still under study. Also, a new variable describing rotation of star configurations is proposed

Determination of phase space region for cross-check validation of the neutron detection in the BINA experiments

Deuteron breakup reactions are basic laboratories for testing nuclear force models. Recent improvements in the data analysis allow for direct identification of neutrons in the BINA detection setup. This opens up the opportunity to study new aspects of few-nucleon system dynamics like charge dependence of nuclear force or Coulomb interaction. In this paper we determine regions along the kinematical curves where differential cross section of deuteron-proton breakup reactions can be measured by the proton-neutron and proton-proton coincidences simultaneously. This is particularly useful for validation of the neutron detection technique