The Living Dead: the Uncanny and Nineteenth-Century Moral Panic over Premature Burial

The fear of premature burial during the nineteenth century escalated to a phenomenon of moral panic. Fueled by the imperfections of the cardiorespiratory standard of death, which allowed for mistakes in pronouncing a person dead, and by the feeling of the uncanny connected to doubts whether an object – a corpse – is animate or inanimate, the moral panic surfaced in a number of forms, including literature, journalism, but also science and legislation. The present study shows how these forms were both an effect of the panic and, simultaneously, a factor which served to uphold and shape it further

The role of the gynaecologist in the promotion and maintenance of oral health during pregnancy

Objectives: The aim of the study was to assess routine dental examination attendance of pregnant women and a possible impact of gynaecological referrals on the attendance rate. Material and methods: An electronic survey was conducted that was inclusive of women up to 5 years following delivery. The questions related to socio-demographic data, the course of pregnancy and childbirth, and visits to dental office during pregnancy. For statistical analysis, the authors utilized the chi-square test, Spearman’s rank correlation coefficient and odds ratios. A significance level of 0.05 has been assumed. Results: A total of 3455 questionnaires were analyzed encompassing women aged 13.1–45.4 years. The respondents were on average 1.78 ± 1.44 years after childbirth. The population comprises of women in 59.1% from large cities, in 74.8% with higher education and in 41% with good socio-economic status. A total of 62.3% of women from the study population have visited a dentist for a routine dental examination. Gynaecologists have given a simple referral to a dentist to 17.6% of all women. 45.9% of them were further requested to provide back the feedback of their dental consultation. Dental appoint­ments were upheld by 87.3% of referred women and by 56.9% of those without a referral (OR = 5.20 (4.05–6.67); p < 0.001). Among those who were referred, dental appointments were upheld in 91.7% of cases when further asked to provide oral health feedback and in 83.5% of cases in absence of such further request (OR = 2.19 (1.3–3.66); p = 0.003). Conclusions: It was determined that referrals from a gynaecologist, and associated oral health feedback requests increase the frequency of abiding to dental appointments during pregnancy. As such, it is necessary to increase the involvement of gynaecologists in the promotion and maintenance of perinatal oral health

Seismic constraints from a Mars impact experiment using InSight and Perseverance

NASA’s InSight (Interior Exploration using Seismic Investigations, Geodesy and Heat Transport) mission has operated a sophisticated suite of seismology and geophysics instruments on the surface of Mars since its arrival in 2018. On 18 February 2021, we attempted to detect the seismic and acoustic waves produced by the entry, descent and landing of the Perseverance rover using the sensors onboard the InSight lander. Similar observations have been made on Earth using data from both crewed1,2 and uncrewed3,4 spacecraft, and on the Moon during the Apollo era5, but never before on Mars or another planet. This was the only seismic event to occur on Mars since InSight began operations that had an a priori known and independently constrained timing and location. It therefore had the potential to be used as a calibration for other marsquakes recorded by InSight. Here we report that no signal from Perseverance’s entry, descent and landing is identifiable in the InSight data. Nonetheless, measurements made during the landing window enable us to place constraints on the distance–amplitude relationships used to predict the amplitude of seismic waves produced by planetary impacts and place in situ constraints on Martian impact seismic efficiency (the fraction of the impactor kinetic energy converted into seismic energy)

The Living Dead: the Uncanny and Nineteenth-Century Moral Panic over Premature Burial

The fear of premature burial during the nineteenth century escalated to a phenomenon of moral panic. Fueled by the imperfections of the cardiorespiratory standard of death, which allowed for mistakes in pronouncing a person dead, and by the feeling of the uncanny connected to doubts whether an object – a corpse – is animate or inanimate, the moral panic surfaced in a number of forms, including literature, journalism, but also science and legislation. The present study shows how these forms were both an effect of the panic and, simultaneously, a factor which served to uphold and shape it further

Expression of the Selected Proteins of JAK/STAT Signaling Pathway in Diseases with Oral Mucosa Involvement

The JAK/STAT signal pathway is a system of intracellular proteins used by many cytokines and growth factors to express genes responsible for the process of cell activation, proliferation and differentiation. There has been numerous inflammatory and autoimmune diseases identified where the JAK/STAT signaling is disrupted; however, there are only a few papers concerning autoimmune bullous diseases published. The aim of this study was to evaluate the expression of proteins: JAK3, STAT2, STAT4 and STAT6 in epithelium lesions in patients with pemphigus vulgaris (PV), bullous pemphigoid (BP), oral lichen planus (LP) and chronic ulcerative stomatitis (CUS), as well as in the control group. Immunohistochemistry and immunoblotting were used to evaluate expression of selected proteins. We found significantly higher expression of selected JAK/STAT proteins in oral mucosa lesions in study groups in comparison to the control group, which indicates participation of JAK/STAT pathway in pathogenesis of these diseases. In BP and PV there were no increased STAT2 expression, whereas in CUS and LP no increased STAT4 expression occurred. The differences in expression of JAK/STAT proteins in selected disorders have been observed. These results create new potential therapeutic targets for the treatment

Atypical Hemolytic Uremic Syndrome (aHUS) and Adenosine Deaminase (ADA)-Deficient Severe Combined Immunodeficiency (SCID)—Two Diseases That Exacerbate Each Other: Case Report

Hemolytic uremic syndrome (HUS) is defined by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury (AKI). Atypical HUS (aHUS), distinguished by its etiology, is caused by uncontrolled overactivation of the alternative complement pathway. The correct diagnosis of aHUS is complex and involves various gene mutations. Severe combined immunodeficiency (SCID), characterized by severe T-cell lymphocytopenia and a lack of antigen-specific T-cell and B-cell immune responses, is of seldom occurrence. In 10–15% of pediatric patients, SCID is caused by adenosine deaminase (ADA) deficiency. The authors describe the case of a boy who suffered from both aHUS and ADA-deficient SCID. At the age of 9 months, the patient presented acute kidney injury with anuria and coagulopathy. The diagnosis of aHUS was established on the basis of alternative complement pathway deregulation and disease-associated gene mutations. Further examination revealed immune system failure and, at the age of 13 months, the ADA deficiency was confirmed by genetic tests and the boy was diagnosed with ADA-SCID. ADA SCID has recently been described as a possible triggering factor of aHUS development and progression. However, more research is required in this field. Nevertheless, it is crucial in clinical practice to be aware of these two co-existing life-threatening diseases

Two Seismic Events from InSight Confirmed as New Impacts on Mars

We report confirmed impact sources for two seismic events on Mars detected by the NASA InSight mission. These events have been positively associated with fresh impact craters identified from orbital images, which match predicted locations and sizes to within a factor of 3, and have formation time constraints consistent with the seismic event dates. They are both of the very high frequency family of seismic events and are present with chirps (dispersed infrasound/acoustic waves). This brings the total number of confirmed Martian impact-related seismic events to eight thus far. All seismic events with chirp signals have now been confirmed as having been caused by impact cratering events. This includes all seismic activity within 100 km of the lander and two out of the four events with source locations between 100 and 300 km distance.ISSN:2632-333

Two seismic events from InSight confirmed as new impacts on Mars

We report confirmed impact sources for two seismic events on Mars detected by the NASA InSight mission. These events have been positively associated with fresh impact craters identified from orbital images, which match predicted locations and sizes to within a factor of three, and have formation time constraints consistent with the seismic event dates. They are both of the Very High Frequency family of seismic events and present with chirps (dispersed infrasound/acoustic waves). This brings the total number of confirmed martian impact-related seismic events to eight thus far. All seismic events with chirp signals have now been confirmed as having been caused by impact cratering events. This includes all seismic activity within 100 km of the lander, and two out of the four events with source locations between 100-300 km distance

Questions to Heaven: InSight's attempted detection of Zhurong's arrival at Mars

Benjamin Fernando and colleagues report on the international cooperation involved InSight's attempt to gather seismic data from the arrival at Mars of China's Zhurong rover

Seismic constraints from a Mars impact experiment using InSight and Perseverance

NASA's InSight (Interior Exploration using Seismic Investigations, Geodesy and Heat Transport) mission has operated a sophisticated suite of seismology and geophysics instruments on the surface of Mars since its arrival in 2018. On 18 February 2021, we attempted to detect the seismic and acoustic waves produced by the entry, descent and landing of the Perseverance rover using the sensors onboard the InSight lander. Similar observations have been made on Earth using data from both crewed(1,2) and uncrewed(3,4) spacecraft, and on the Moon during the Apollo eras(5), but never before on Mars or another planet. This was the only seismic event to occur on Mars since InSight began operations that had an a priori known and independently constrained timing and location. It therefore had the potential to be used as a calibration for other marsquakes recorded by InSight. Here we report that no signal from Perseverance's entry, descent and landing is identifiable in the InSight data. Nonetheless, measurements made during the landing window enable us to place constraints on the distance-amplitude relationships used to predict the amplitude of seismic waves produced by planetary impacts and place in situ constraints on Martian impact seismic efficiency (the fraction of the impactor kinetic energy converted into seismic energy).ISSN:2397-336