437 research outputs found
A Model for Determining Attitudes Towards School District Reorganization
The focus of this study is to provide a model for determining current attitudes toward school district reorganization so that a school board can gain local community data. The small rural school districts of central Illinois are finding fewer and fewer options when considering maintaining or increasing the quality of education in their communities. Illinois school reform legislation of 1985 included a section on school district reorganization which was an effort to reduce the number of districts and increase the quality of education. However, the sentiment was so strong against forced reorganization that the plan for reorganization died a political death. After a review of the literature and research, a model was developed for identifying local influential groups who were questioned on common areas of concern about reorganization. In the application of the model, influentials in Tuscola, Arcola, Atwood/Hammond, and Villa Grove school districts were surveyed for their attitudes toward reorganization. An analysis of the data collected showed the areas of concern in each of the surveyed districts, and the problems that each board must confront if reorganization is to be a viable option at some time for its district. The data collected indicated a strong concern for the welfare of the business life of the community and a desire to retain control of the local schools
A Model for Determining Attitudes Towards School District Reorganization
The focus of this study is to provide a model for determining current attitudes toward school district reorganization so that a school board can gain local community data. The small rural school districts of central Illinois are finding fewer and fewer options when considering maintaining or increasing the quality of education in their communities. Illinois school reform legislation of 1985 included a section on school district reorganization which was an effort to reduce the number of districts and increase the quality of education. However, the sentiment was so strong against forced reorganization that the plan for reorganization died a political death. After a review of the literature and research, a model was developed for identifying local influential groups who were questioned on common areas of concern about reorganization. In the application of the model, influentials in Tuscola, Arcola, Atwood/Hammond, and Villa Grove school districts were surveyed for their attitudes toward reorganization. An analysis of the data collected showed the areas of concern in each of the surveyed districts, and the problems that each board must confront if reorganization is to be a viable option at some time for its district. The data collected indicated a strong concern for the welfare of the business life of the community and a desire to retain control of the local schools
Characterization of Aminoisobutyric Acid Transport Systems in MCF-8, a Line of Malignant Mouse Mammary Epithelial Cells
Uptake of α-aminoisobutyric acid (AIB) by MCF-8, a line of malignant mouse mammary epithelial cells derived from a D2 hyperplastic nodule outgrowth, was found to be mediated by two different transport systems. In actively dividing cells about 60% of total AIB uptake is mediated by an A-like system: transport was Na+ -dependent, was inhibited by N-methyl-AIB, was maximal at pH 7.5 and ceased at pH 6. Transport by this system was reduced by nearly 65% when cell division ceased in confluent cultures, but the addition of insulin and/or calf serum to the medium of quiescent cells restored activity. Transport by the A system had a Km of 1.0 mM AIB and Vmax of 5.5 pM AIB transported per μg cellular protein per minute. About 20% of total AIB uptake was mediated by an L-like transport system which was Na+ -independent, was inhibited by α-2-aminobicyclo (2,2, l)-heptane-2-carboxylic acid, and was active at both pH 7.5 and pH 6. The activity of the L system was not influenced by cell growth rate or by insulin or serum. The remaining 20% of total AIB uptake occurs via a non-saturable route. No ASC-like system was detected
Excitation functions for (p,x) reactions of niobium in the energy range of E = 40-90 MeV
A stack of thin Nb foils was irradiated with the 100 MeV proton beam at Los
Alamos National Laboratory's Isotope Production Facility, to investigate the
Nb(p,4n)Mo nuclear reaction as a monitor for intermediate energy
proton experiments and to benchmark state-of-the-art reaction model codes. A
set of 38 measured cross sections for Nb(p,x) and
Cu(p,x) reactions between 40-90 MeV, as well as 5 independent
measurements of isomer branching ratios, are reported. These are useful in
medical and basic science radionuclide productions at intermediate energies.
The Cu(p,x)Co, Cu(p,x)Zn, and
Cu(p,x)Zn reactions were used to determine proton
fluence, and all activities were quantified using HPGe spectrometry. Variance
minimization techniques were employed to reduce systematic uncertainties in
proton energy and fluence, improving the reliability of these measurements. The
measured cross sections are shown to be in excellent agreement with literature
values, and have been measured with improved precision compared with previous
measurements. This work also reports the first measurement of the
Nb(p,x)Rb reaction, and of the independent cross
sections for Cu(p,x)Mn and
Nb(p,x)Y in the 40-90 MeV region. The effects of
Si(p,x)Na contamination, arising from silicone
adhesive in the Kapton tape used to encapsulate the aluminum monitor foils, is
also discussed as a cautionary note to future stacked-target cross section
measurements. \emph{A priori} predictions of the reaction modeling codes CoH,
EMPIRE, and TALYS are compared with experimentally measured values and used to
explore the differences between codes for the Nb(p,x) and
Cu(p,x) reactions.Comment: 34 pages, submitted to NIM-
Impaired Skeletal Muscle Blood Flow Control With Advancing Age in Humans: Attenuated ATP Release and Local Vasodilation During Erythrocyte Deoxygenation
Rationale: Skeletal muscle blood flow is coupled with the oxygenation state of hemoglobin in young adults, whereby the erythrocyte functions as an oxygen sensor and releases ATP during deoxygenation to evoke vasodilation. Whether this function is impaired in humans of advanced age is unknown. Objective: To test the hypothesis that older adults demonstrate impaired muscle blood flow and lower intravascular ATP during conditions of erythrocyte deoxygenation. Methods and Results: We showed impaired forearm blood flow responses during 2 conditions of erythrocyte deoxygenation (systemic hypoxia and graded handgrip exercise) with age, which was caused by reduced local vasodilation. In young adults, both hypoxia and exercise significantly increased venous [ATP] and ATP effluent (forearm blood flow×[ATP]) draining the skeletal muscle. In contrast, hypoxia and exercise did not increase venous [ATP] in older adults, and both venous [ATP] and ATP effluent were substantially reduced compared with young people despite similar levels of deoxygenation. Next, we demonstrated that this could not be explained by augmented extracellular ATP hydrolysis in whole blood with age. Finally, we found that deoxygenation-mediated ATP release from isolated erythrocytes was essentially nonexistent in older adults. Conclusions: Skeletal muscle blood flow during conditions of erythrocyte deoxygenation was markedly reduced in aging humans, and reductions in plasma ATP and erythrocyte-mediated ATP release may be a novel mechanism underlying impaired vasodilation and oxygen delivery during hypoxemia with advancing age. Because aging is associated with elevated risk for ischemic cardiovascular disease and exercise intolerance, interventions that target erythrocyte-mediated ATP release may offer therapeutic potential
Why Some Interfaces Cannot be Sharp
A central goal of modern materials physics and nanoscience is control of
materials and their interfaces to atomic dimensions. For interfaces between
polar and non-polar layers, this goal is thwarted by a polar catastrophe that
forces an interfacial reconstruction. In traditional semiconductors this
reconstruction is achieved by an atomic disordering and stoichiometry change at
the interface, but in multivalent oxides a new option is available: if the
electrons can move, the atoms don`t have to. Using atomic-scale electron energy
loss spectroscopy we find that there is a fundamental asymmetry between
ionically and electronically compensated interfaces, both in interfacial
sharpness and carrier density. This suggests a general strategy to design sharp
interfaces, remove interfacial screening charges, control the band offset, and
hence dramatically improving the performance of oxide devices.Comment: 12 pages of text, 6 figure
Nanoscale grains, high irreversibility field, and large critical current density as a function of high energy ball milling time in C-doped magnesium diboride
Magnesium diboride (MgB2) powder was mechanically alloyed by high energy ball
milling with C to a composition of Mg(B0.95C0.05)2 and then sintered at 1000 C
in a hot isostatic press. Milling times varied from 1 minute to 3000 minutes.
Full C incorporation required only 30-60 min of milling. Grain size of sintered
samples decreased with increased milling time to less than 30 nm for 20-50 hrs
of milling. Milling had a weak detrimental effect on connectivity. Strong
irreversibility field (H*) increase (from 13.3 T to 17.2 T at 4.2 K) due to
increased milling time was observed and correlated linearly with inverse grain
size (1/d). As a result, high field Jc benefited greatly from lengthy powder
milling. Jc(8 T, 4.2 K) peaked at > 80,000 A/cm2 with 1200 min of milling
compared with only ~ 26,000 A/cm2 for 60 min of milling. This non-compositional
performance increase is attributed to grain refinement of the unsintered powder
by milling, and to the probable suppression of grain growth by milling-induced
MgO nano-dispersions.Comment: 12 pages, 11 figure
Domain configurations in Co/Pd and L10-FePt nanowire arrays with perpendicular magnetic anisotropy
Perpendicular magnetic anisotropy [Co/Pd]15 and L10-FePt nanowire arrays of
period 63 nm with linewidths 38 nm and 27 nm and film thickness 27 nm and 20 nm
respectively were fabricated using a self-assembled PS-b-PDMS diblock copolymer
film as a lithographic mask. The wires are predicted to support Neel walls in
the Co/Pd and Bloch walls in the FePt. Magnetostatic interactions from nearest
neighbor nanowires promote a ground state configuration consisting of
alternating up and down magnetization in adjacent wires. This was observed over
~75% of the Co/Pd wires after ac-demagnetization but was less prevalent in the
FePt because the ratio of interaction field to switching field was much
smaller. Interactions also led to correlations in the domain wall positions in
adjacent Co/Pd nanowires. The reversal process was characterized by nucleation
of reverse domains, followed at higher fields by propagation of the domains
along the nanowires. These narrow wires provide model system for exploring
domain wall structure and dynamics in perpendicular anisotropy systems
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