274 research outputs found
Teenagers’ vandalism and the importance of parent-child relationships in addressing it
Vandalism in the urban environment is a common phenomenon but is difficult to evaluate. The scale of damage caused by vandalism is rarely analyzed, and therefore a limited number of scientific works are devoted to the phenomenon of vandal behavior and the identification of its causes. While the role of the family in the formation of deviant behavior is indicated by many researchers, the context of vandalism and the issue of family determination remains open. This article studies the parents’ styles of upbringing and their preparation for teenagers’ vandal behavior. By identifying the degree of influence of the family in the formation of such a destructive form of interaction between teenagers’ and the material environment it is possible to identify a group of teenagers who are ready to commit acts of vandalism. An attempt is made to correlate child-parent relations with teenagers’ motivational readiness to commit acts of vandalism. To study the relationship of child-parent relations and teenagers’ vandal behavior, data was collected (using psycho-diagnostic techniques) from 60 teenagers and their parents from complete and incomplete families, the socially well-off and the socially disadvantaged. The results were processed using descriptive statistics, MANOVA and linear regression analysis. It was found that parental upbringing styles play a decisive role in initiating vandalism, while the educational effects of mother and father have their own specific characteristics. The results can be used in the organization of social support for children from socially disadvantaged families in order to prevent vandalism and its radicalization. © 2018, Kazan Federal University. All rights reserved
SWI/SNF Chromatin Remodeling Complex Involved in RNA Polymerase II Elongation Process in Drosophila melanogaster
Fortification of food with micronutrients: development of methodological and regulatory framework in the Russian Federation
The available scientific literature, domestic and international regulatory codes of normative documents concerning the fortification of various types of food products have been analyzed. The groups of food products of conventional and regular consumption included into the diets of all categories of consumers, recommended for fortification with essential micronutrients, have been determined: wheat and cereal flour (spelt wheat, buckwheat, oat, corn flour, etc.); pastry; milk and dairy products, including ice cream; non-alcoholic soft drinks; mineralized drinking water; fruit and vegetable juices; fat and oil products (vegetable oils, margarines, spreads, mayonnaise); confectionery and sweets (pastry, sugar, chocolate); cereals (breakfast cereals, muesli, ready-to-eat extruded cereals, instant pasta and cereals, mixtures for bakery, flour for sweet pastry); food concentrates (jelly, instant drinks, concentrates of sweet foods, instant food, instant cereal concentrates); table salt. The groups of food products assigned for certain categories of population are used as part of therapeutic diets for patients with various diseases (metabolic disorder syndrome, cardio-vascular system pathology with atherosclerotic vascular injury, type 2 diabetes mellitus, gastrointestinal tract diseases, non-alcoholic fatty liver disease, diabetic nephropathy, etc.), as well as assigned to reduce the risk of diseases developing, the nutrients are recommended for targeted fortification of certain types of food. Examples of micronutrients fortification of sausages and minced meat semifinished products are given below. Requirements for fortification of mass consumption food products and for fortification of foods for special dietary uses are formulated in this article, the amount of fortifying components in the various groups of food products are justified, ensuring their efficiency for improving the micronutrient status and safety of its consumption. Based on the analysis of the available scientific literature, domestic and international regulatory framework of normative documents on fortification of various types of food products, recommendations have been developed for fortification of food with micronutrients
Mechanisms of transcriptional regulation of ecdysone response
The mechanisms of ecdysone-dependent expression have been studied for many decades. Initially, the activation of individual genes under the influence of ecdysone was studied on the model of polythene chromosomes from salivary glands of Drosophila melanogaster. These works helped to investigate the many aspects of the Drosophila development. They also revealed plenty of valuable information regarding the fundamental mechanisms controlling the genes’ work. Many years ago, a model describing the process of gene activation by ecdysone, named after the author – Ashburner model – was proposed. This model is still considered an excellent description of the ecdysone cascade, which is implemented in the salivary glands during the formation of the Drosophila pupa. However, these days there is an opinion that the response of cells to the hormone ecdysone can develop with significant differences, depending on the type of cells. The same genes can be activated or repressed under the influence of ecdysone in different tissues. Likely, certain DNA-binding transcription factors that are involved in the ecdysonedependent response together with the EcR/Usp heterodimer are responsible for cell-type specificity. A number of transcriptional regulators involved in the ecdysone response have been described. Among them are several complexes responsible for chromatin remodeling and modification. It has been shown by various methods that ecdysone-dependent activation/repression of gene transcription develops with significant structural changes of chromatin on regulatory elements. The description of the molecular mechanism of this process, in particular, the role of individual proteins in it, as well as structural interactions between various regulatory elements is a matter of the future. This review is aimed to discuss the available information regarding the main regulators that interact with the ecdysone receptor. We provide a brief description of the regulator’s participation in the ecdysone response and links to the corresponding study. We also discuss general aspects of the mechanism of ecdysone-dependent regulation and highlight the most promising points for further research
Comparative analysis of models kinetic scheme of the numerical calculations of nitrogen oxide at pulverized solid fuel
Multi-Drug Resistance of Mycobacterium Tuberculosis – the Problem of Modern Phthisiology
The 21st century is characterized by the exacerbation of the problem formation and spreading of drug-resistant strains throughout the world. Genetic mutations of Mycobacterium tuberculosis lead to the formation of drug-resistant forms because of long-term use of anti-tuberculosis drugs. The Russian Federation is among the top three countries with a high burden of tuberculosis with multidrug resistance (MDR). The estimated number of cases of tuberculosis with MDR in the Russian Federation was 60,000, which corresponds to half the burden of the European Region in 2015. In the Irkutsk region from 2014 till 2018 the proportion of TB cases with MDR cases increased from 15.2 % to 18.3 %. According to the reference laboratory of the Irkutsk Regional Clinical Tuberculosis Hospital, a significantly higher level of MDR among primary diagnosed was registered in the cities (27.7 %) and the lowest in rural areas of the region (16.5 %). Among the cohorts of patients with tuberculosis, the highest proportion of MDR was in the northern territories of the region (43.1 %), in Irkutsk district (41.2 %) and in large cities, including Irkutsk (38.5 %). Positive correlations were established between cohort of primary diagnosed TB with MDR and among populations in areas with high morbidity along the railway (r = 0.91; p = 0.00001), in the Irkutsk region (r = 0.89; p = 0,00008), and also in the Irkutsk city (r = 0.91; p = 0.00002). This is probably due to the influence of reservoir of tuberculosis infection formed in these localities. The regulatory documents of the Ministry of Health of the Irkutsk Region was developed on the basis of the data obtained, and they include recommendations for improving the diagnosis of tuberculosis in the region using fast and accelerated microbiological diagnostic methods
CLINICAL EFFICACY OF MONOTHERAPY WITH INDAPAMIDE IN PATIENTS WITH ARTERIAL HYPERTENSION OF THE I-II DEGREES
Aim. To assess antihypertensive efficacy of monotherapy with indapamide (Akripamide, Akrihin, Russia) and its influence on blood levels of carbohydrates, lipids and electrolytes in patients with essential hypertension (EH). Methods. 30 patients with EH I-II degrees were treated with indapamide 2,5 mg daily during 3 months. Ambulatory blood pressure (BP) monitoring was made before and after the treatment as well as blood levels of carbohydrates, lipids and electrolytes were assessed. Results. 3-month indapamide monotherapy resulted in achievement of BP target levels in 76.6% of patients. Significant decrease in daily , day-time and nighttime BP , BP burden and daytime BP variability were observed. Number of patients with insufficient night decrease of systolic and diastolic BP was significantly decreased. No negative influence of indapamide on blood levels of lipids and electrolytes was observed. Conclusion. Indapamide is effective antihypertensive drug with satisfactory tolerance
Project approach to training teachers for secondary vocational education
При проектном подходе к подготовке педагогических кадров для среднего профессионального образования изменяются взаимоотношения между заказчиками – учебными заведениями СПО и профессионально-педагогическим вузом, отвечающим за подготовку квалифицированных педагогов профессионального обученияThe design approach to the preparation of teachers for secondary vocational education changed the relationship between customers – educational institutions of secondary vocational and vocational-pedagogical University responsible for the training of qualified, meeting the requirements of the act, teachers of vocational trainin
EMPATHY AND EMOTIONAL INTELLIGENCE IN PSYCHOLOGY STUDENTS
A pronounced ability for empathy and high emotional intelligence are considered as important components of the profession of a psychologist. The study of empathy abilities and emotional intelligence of students-psychologists in comparison with students of the control group was carried out. The results obtained indicate a high level of empathy abilities among psychology students and the relationship of empathy ability with emotional intelligence and its components.Выраженная способность к эмпатии и высокий эмоциональный интеллект рассматриваются как важные составляющие профессии психолога. Выполнено исследование способностей к эмпатии и эмоционального интеллекта студентов-психологов в сравнении со студентами контрольной группы. Полученные результаты свидетельствуют о высоком уровне способностей к эмпатии у студентов-психологов и о взаимосвязи способности к эмпатии с эмоциональным интеллектом и его компонентами
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