16 research outputs found
RENO, a European Postmarket Surveillance Registry, confirms effectiveness of coronary brachytheraypy in routine clinical practice.
Purpose: To assess, by a European registry trial, the clinical event rate in patients with discrete stenotic lesions of coronary arteries (de novo or restenotic) in single or multiple vessels (native or bypass grafts) treated with -radiation.
Methods and Materials: Between April 1999 and September 2000, 1098 consecutive patients treated in 46 centers in Europe and the Middle East with the Novoste Beta-Cath System were included in Registry Novoste (RENO).
Results: Six-month follow-up data were obtained for 1085 patients. Of 1174 target lesions, 94.1% were located in native vessels and 5.9% in a bypass graft; 17.7% were de novo lesions, 4.1% were restenotic, and 77.7% were in-stent restenotic lesions. Intravascular brachytherapy was technically successful in 95.9% of lesions. Multisegmental irradiation, using a manual pullback stepping maneuver to treat longer lesions, was used in 16.3% of the procedures. The in-hospital rate of major adverse cardiac events was 1.8%. At 6 months, the rate was 18.7%.
Angiographic follow-up was available for 70.4% of the patients. Nonocclusive restenosis was seen in 18.8% and total occlusion in 5.7% of patients. A combined end point for late (30–180 days) definitive or suspected target vessel closure was reached in 5.4%, but with only 2% of clinical events. Multivariate analysis was performed for major adverse cardiac events and late thrombosis.
Conclusion: Data obtained from the multicenter RENO registry study, derived from a large cohort of unselected consecutive patients, suggest that the good results of recent randomized controlled clinical trials can be replicated in routine clinical practice. © 2003 Elsevier Science Inc
Optical properties of MgH2 measured in situ in a novel gas cell for ellipsometry/spectrophotometry
The dielectric properties of alpha-MgH2 are investigated in the photon energy
range between 1 and 6.5 eV. For this purpose, a novel sample configuration and
experimental setup are developed that allow both optical transmission and
ellipsometric measurements of a transparent thin film in equilibrium with
hydrogen. We show that alpha-MgH2 is a transparent, colour neutral insulator
with a band gap of 5.6 +/- 0.1 eV. It has an intrinsic transparency of about
80% over the whole visible spectrum. The dielectric function found in this work
confirms very recent band structure calculations using the GW approximation by
Alford and Chou [J.A. Alford and M.Y. Chou (unpublished)]. As Pd is used as a
cap layer we report also the optical properties of PdHx thin films.Comment: REVTeX4, 15 pages, 12 figures, 5 table