6 research outputs found
Do the cosmological observational data prefer phantom dark energy?
The dynamics of expansion and large scale structure formation of the Universe
are analyzed for models with dark energy in the form of a phantom scalar field
which initially mimics a -term and evolves slowly to the Big Rip
singularity. The discussed model of dark energy has three parameters -- the
density and the equation of state parameter at the current epoch,
and , and the asymptotic value of the equation of state parameter at
, . Their best-fit values are determined jointly
with all other cosmological parameters by the MCMC method using observational
data on CMB anisotropies and polarization, SNe Ia luminosity distances, BAO
measurements and more. Similar computations are carried out for CDM
and a quintessence scalar field model of dark energy. It is shown that the
current data slightly prefer the phantom model, but the differences in the
maximum likelihoods are not statistically significant. It is also shown that
the phantom dark energy with monotonically increasing density in future will
cause the decay of large scale linear matter density perturbations due to the
gravitational domination of dark energy perturbations long before the Big Rip
singularity.Comment: 13 pages, 8 figures, 5 tables; comments and references added; version
accepted for publication in Phys.Rev.
Perspectives of the inhaled antibiotics usage in pediatrics
The antibacterial therapy in children remains a complicated and an unsolved problem of medicine. Despite the fact that antibiotics are largely available, every year more and more bacteria become resistant to these drugs. Also, there is only a small number of new antibacterial agents introduced into practice, especially for respiratory system infections. This is due to the fact that systemic antibiotics poorly penetrate into the pulmonary tissue and do not create high concentrations at the site of inflammation. With increased doses of systemic antibacterial agents, their toxic effect on the body of the patient also increases. Therefore, the usage of inhalation route for the intake of these agents is a modern one and reduces the risk of systemic side effects. In the literature review conducted by us, the main advantages of inhalation intake of antibiotics have been examined, the analysis of the basic preparations usage has been carried out and the disadvantages and side effects of the inhalation route of the antibacterial agents intake have been identified. It is also worth noting that the inhaled antibiotics are practically not used as monotherapy, but only in combination with antibiotics with systemic action. They cannot be an alternative or a substitute for systemic drugs. The usage of this group of drugs makes it possible to improve the results of treatment of the respiratory diseases in children, especially with chronic inflammatory processes. The inhaled antibiotics can be one more important step in the fight against antibiotic resistance
ΠΠΎΡΠ΅Π½Π΅Π·Π±ΠΈΡΠ°Π»ΡΠ½Π° ΠΌΠ°ΡΠΈΠ½Π°
1. ΠΠΎΡΠ΅Π½Π΅Π·Π±ΠΈΡΠ°Π»ΡΠ½Π° ΠΌΠ°ΡΠΈΠ½Π°, ΡΠΎ ΠΌΡΡΡΠΈΡΡ ΡΠ°ΒΠΌΡ, Π½Π° ΡΠΊΡΠΉ Π² ΡΡΠ΄ ΡΠΎΠ·ΡΠ°ΡΠΎΠ²Π°Π½Ρ ΠΊΠΎΠΏΡΡΡΡΡ ΠΊΠΎΠ»Π΅ΡΠ°, ΠΏΡΠΈΡΡΡΡΠΉ Π΄Π»Ρ Π°Π²ΡΠΎΠΌΠ°ΡΠΈΡΠ½ΠΎΠ³ΠΎ Π²Π΅Π΄Π΅Π½Π½Ρ ΠΌΠ°ΡΠΈΠ½ΠΈ ΠΏΠΎ ΡΡΠ΄ΠΊΠ°Ρ
ΠΊΠΎΡΠ΅Π½Π΅ΠΏΠ»ΠΎΠ΄ΡΠ², Π²ΠΈΠΊΠΎΠΏΡΡΡΡ ΡΠΎΠ±ΠΎΡΡ ΠΎΡΠ³Π°Π½ΠΈ, ΠΎΡΠΈΡΠ½Ρ Π²Π°Π»ΠΈ, ΠΏΡΡΡΠΊΠΎΠ²ΠΈΠΉ ΡΡΠ°Π½ΡΠΏΠΎΡΡΠ΅Ρ, Π±ΡΠ½ΠΊΠ΅Ρ, Π·Π°Π΄Π½ΡΠΉ ΠΌΡΡΡ, Π²ΡΠ΄ΡΡΠ·Π½ΡΡΡΡΡΡ ΡΠΈΠΌ, ΡΠΎ ΡΡΠ°Π½ΡΠΏΠΎΡΡΠ΅Ρ Π²ΠΈΒΠΊΠΎΠ½Π°Π½ΠΈΠΉ Π· Π΄Π²ΠΎΡ
ΡΠ°ΡΡΠΈΠ½ Π-ΠΏΠΎΠ΄ΡΠ±Π½ΠΎΡ ΡΠΎΡΠΌΠΈ, ΠΏΠ΅ΡΡΠ° ΡΠ°ΡΡΠΈΠ½Π° ΡΠΊΠΎΠ³ΠΎ ΡΡΠ²ΠΎΡΡΡ Π³ΠΎΡΡΡΠΈΠΉ ΠΊΡΡ Π· Π³ΠΎΡΠΈΠ·ΠΎΠ½ΡΠ°Π»ΡΒΠ½ΠΎΡ ΠΏΠ»ΠΎΡΠΈΠ½ΠΎΡ, ΠΏΡΠΈΡΠΎΠΌΡ Π½Π°ΠΏΡΡΠΌΠΎΠΊ ΠΊΡΡΠ° Π½Π°ΠΏΡΠ°Π²Π»Π΅ΒΠ½ΠΈΠΉ Π² ΡΡΠΎΡΠΎΠ½Ρ Π½Π°ΠΏΡΡΠΌΠΊΡ ΡΡΡ
Ρ ΠΌΠ°ΡΠΈΠ½ΠΈ. 2. ΠΠΎΡΠ΅Π½Π΅Π·Π±ΠΈΡΠ°Π»ΡΠ½Π° ΠΌΠ°ΡΠΈΠ½Π° ΠΏΠΎ ΠΏ.1, Π²ΡΠ΄ΡΡΠ·Π½ΡΡΡΡΡΡ ΡΠΈΠΌ, ΡΠΎ ΠΏΠΎΠ»ΠΎΡΠ½ΠΎ Π-ΠΏΠΎΠ΄ΡΠ±Π½ΠΎΠ³ΠΎ ΡΡΠ°Π½ΡΠΏΠΎΡΡΠ΅ΡΡ Π²ΠΈΠΊΠΎΠ½Π°Π½Π΅ Π· Π΅Π»Π°ΡΡΠΈΡΠ½ΠΈΡ
ΡΡΡΡΡΠΎΠΊ, ΡΠΎ ΠΌΠ°ΡΡΡ Π²Π½ΡΡΡΡΡΠ½Ρ Π·Π°ΡΠ΅ΠΏΠΈ, Π΄ΠΎ ΡΠΊΠΈΡ
ΠΏΡΠΈΠΊΡΡΠΏΠ»Π΅Π½Ρ ΠΏΡΡΡΠΊΠΈ Π· Π½Π΅ΡΡΡΠΈΠΌΠΈ ΡΠΊΡΠ΅Π±ΠΊΠ°ΠΌΠΈ