Outage performance analysis of non-orthogonal multiple access systems with RF energy harvesting

Non-orthogonal multiple access (NOMA) has drawn enormous attention from the research community as a promising technology for future wireless communications with increasing demands of capacity and throughput. Especially, in the light of fifth-generation (5G) communication where multiple internet-of-things (IoT) devices are connected, the application of NOMA to indoor wireless networks has become more interesting to study. In view of this, we investigate the NOMA technique in energy harvesting (EH) half-duplex (HD) decode-and-forward (DF) power-splitting relaying (PSR) networks over indoor scenarios which are characterized by log-normal fading channels. The system performance of such networks is evaluated in terms of outage probability (OP) and total throughput for delay-limited transmission mode whose expressions are derived herein. In general, we can see in details how different system parameters affect such networks thanks to the results from Monte Carlo simulations. For illustrating the accuracy of our analytical results, we plot them along with the theoretical ones for comparison

Overcoming Fear of Developing Country: A Case Report of Retroperitoneal Laparoscopic Partial Nephrectomy for T3a Renal Cell Carcinoma

INTRODUCTION: Renal cell carcinoma poses significant challenges in kidney diseases, particularly in the context of the T3 stage, where treatment strategies remain controversial. The utilization of laparoscopic partial nephrectomy, particularly in developing countries, has been restricted for such patients, primarily due to limited infrastructure and concerns about recurrence risk and long-term pathologic outcomes. PRESENTATION OF CASE: In this report, we present a case of a 64-year-old male diagnosed with T3aN0M0 renal cell carcinoma (RCC). Abdominal computed tomography revealed a 5.2 × 5.2 × 5.1 cm mass on the right upper part of the kidney with a possible thrombus in the superior renal polar vein. The patient underwent successful treatment with retroperitoneal laparoscopic partial nephrectomy (LPN), leading to the preservation of kidney function with/min/1.73 m2 GFR reduced after one year postoperative (estimated GFR from 85 mL/min/1.73 m2 to 81.79 mL/min/1.73 m2). The patient was discharged after three days; no recurrence was observed during the follow-up. DISCUSSION: For stage T3a RCC, studies show that LPN induces comparable long-term outcomes to radical nephrectomy, with advantages such as preserved kidney function, reduced operative time, blood loss, and shorter hospital stays. However, due to infrastructure constraints and limited access to robotic-assisted surgery in our country, coupled with concerns about tumor recurrence, laparoscopic radical nephrectomy is predominantly employed for similar patients. Our case represents one of the very first cases in which we successfully treated a patient diagnosed with T3a RCC using retroperitoneal laparoscopic partial nephrectomy. CONCLUSION: Laparoscopic partial nephrectomy is a reliable choice for T3aN0M0 RCC with good long-term outcomes and preserved renal function, especially by the hands of an experienced laparoscopic surgeon

STATE-OF-THE-ART TECHNIQUES TO PERFORM AN INDUSTRIAL VIBRATION TEST CAMPAIGN AND A RAPID PROCESS TO UPDATE RENEWED FEM FOR CLEARANCE OF FIRST FLIGHT TEST

After the realization of the GVT (Ground Vibration Testing) campaigns on the AIRBUS A350 XWB 900 in 2013, the ONERA-DLR specialized joined team performed the GVT of the A320 NEO Pratt & Whitney powered in July 2014. The specifications of this test were particularly oriented to the updating of a renewed FEM (Finite Element Model) of this new version of the A320. Concerning the GVT, the latest improvements on developed methods and tools were applied, making the completion of the test successful in 7 measurement days for 2 mass configurations. Concerning the GVT, the very short time devoted to this campaign imposed by a strict and busy planning from the program leaders required to reinforce in one hand the test techniques and methods, mixing PSM (Phase Separation Methods) and PRM (Phase Resonance Methods) and to optimize in the other hand the workflow and the data deliveries to meet the challenging test requirements. This paper describes the processes followed and the methods used in this particularly hard context and how those contributed to the successful achievement of this challenging test campaign. Concerning the FEM updating, an optimized process has been applied to update the renewed FEM, especially focusing on the updated components such as pylons, engines, wings and sharklets. This process - including correlation analysis, tuning FEM then validating tuned FEM w.r.t GVT - has provided a means to tune FEM within a short time to support clearance of first flight test

Hyperhomocysteinemia in Patients with Newly Diagnosed Primary Hypertension in Can Tho City, Vietnam

Background: Elevated levels of blood total homocysteine is one of the cardiovascular risk factors in hypertensive patients. Objectives: Determine the prevalence of hyperhomocysteinemia and its associated factors in newly diagnosed primary hypertension patients. Materials and methods: A cross-sectional descriptive study on 105 patients with newly diagnosed primary hypertension at Can Tho University of Medicine and Pharmacy Hospital from May 2017 to May 2018. Total homocysteine levels and related factors were collected at the study time. Results: The mean plasma total homocysteine level was 16.24 ± 4.49 µmol/L. There were 78 patients with elevated plasma total homocysteine levels ≥15 µmol/L, accounting for 74.3% of all patients. Being elderly, gender, hypertension stage, and diabetes were factors associated with hyperhomocysteinemia (p < 0.05). Total homocysteine levels were positively correlated with SBP, DBP, and age with r(SBP) = 0.696, r(DBP) = 0.585, and r(age) = 0.286. Conclusion: Research on the subpopulation of Vietnamese people shows that hyperhomocysteinemia is common in patients with newly diagnosed primary hypertension, and high blood total homocysteine levels are often related to age, sex, hypertension stage, and diabetes

Nimbandiolactone-21 and nimbandioloxyfuran, two new 28-norlimonoids from the leaves of <i>Azadirachta indica</i> (Meliaceae)

<p>From an EtOAc-soluble fraction of the leaves of <i>Azadirachta indica</i>, two new 28-norlimonoids named nimbandiolactone-21 (<b>1</b>) and nimbandioloxyfuran (<b>2</b>), together with nimbandiolactone-23 (<b>3</b>), were isolated. Their relative structures were elucidated based on NMR spectroscopic interpretation and biosynthetic consideration. Nimbandioloxyfuran (<b>2</b>) and nimbandiolactone-23 (<b>3</b>) showed potent <i>α</i>-glucosidase inhibitory activity, with the IC₅₀ values of 46.2 and 38.7 <i>μ</i>M, respectively.</p

Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization

Despite their promise, circulating tumor DNA (ctDNA)-based assays for multi-cancer early detection face challenges in test performance, due mostly to the limited abundance of ctDNA and its inherent variability. To address these challenges, published assays to date demanded a very high-depth sequencing, resulting in an elevated price of test. Herein, we developed a multimodal assay called SPOT-MAS (screening for the presence of tumor by methylation and size) to simultaneously profile methylomics, fragmentomics, copy number, and end motifs in a single workflow using targeted and shallow genome-wide sequencing (~0.55×) of cell-free DNA. We applied SPOT-MAS to 738 non-metastatic patients with breast, colorectal, gastric, lung, and liver cancer, and 1550 healthy controls. We then employed machine learning to extract multiple cancer and tissue-specific signatures for detecting and locating cancer. SPOT-MAS successfully detected the five cancer types with a sensitivity of 72.4% at 97.0% specificity. The sensitivities for detecting early-stage cancers were 73.9% and 62.3% for stages I and II, respectively, increasing to 88.3% for non-metastatic stage IIIA. For tumor-of-origin, our assay achieved an accuracy of 0.7. Our study demonstrates comparable performance to other ctDNA-based assays while requiring significantly lower sequencing depth, making it economically feasible for population-wide screening