13 research outputs found

    Influence of sulphide Cu (I) promoting additives concentration on acid and catalytic properties of high-silica zeolites in straight-run gasoline conversion

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    In present article the influence of Cu[2]S promoting additives concentration on acid and catalytic properties of high silica MFI-type zeolites is investigated in the process of conversion of straight-run gasoline fractions of gas condensate into high octane components of motor fuels. It was shown that zeolite modified with 1% of Cu[2]S nanoscaled powder possesses the highest acid centers concentration and highest catalytic activity

    Descriptive review of current practices and prognostic factors in patients with ovarian cancer treated by pressurized intraperitoneal aerosol chemotherapy (PIPAC): a multicentric, retrospective, cohort of 234 patients

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    IntroductionOvarian cancer (OC) is the primary cause of mortality in women diagnosed with gynecological cancer. Our study assessed pressurized intraperitoneal aerosol chemotherapy (PIPAC) as treatment for peritoneal surface metastases (PSM) from recurrent or progressive OC and conducted survival analyses to identify prognostic factors.Material and methodsThis retrospective cohort study, conducted across 18 international centers, analyzed the clinical practices of patients receiving palliative treatment for PSM from OC who underwent PIPAC. All patients were initially treated appropriately outside any clinical trial setting. Feasibility, safety, and morbidity were evaluated along with objective endpoints of oncological response. Multivariate analysis identified prognostic factors for OS and PFS.ResultsFrom 2015-2020, 234 consecutive patients were studied, from which 192 patients were included and stratified by platinum sensitivity for analysis. Patients with early recurrence, within one postoperative month, were excluded. Baseline characteristics were similar between the groups regarding platinum sensitivity (platinum sensitive (PS) and resistant (PR)), but chemotherapy frequency differed, as did PCI before PIPAC. Median PCI decreased in both groups after three cycles of PIPAC (PS 16 vs. 12, p < 0.001; PR 24 vs. 20, p = 0.009). Overall morbidity was 22%, with few severe complications (4-8%) or mortality (0-3%). Higher pathological response and longer OS (22 vs. 11m, p = 0.012) and PFS (12 vs. 7m, p = 0.033) were observed in the PS group. Multivariate analysis (OS/PFS) identified ascites (HR 4.02, p < 0.001/5.22, p < 0.001), positive cytology at first PIPAC (HR 3.91, p = 0.002/1.96, p = 0.035), and ≥ 3 PIPACs (HR 0.30, p = 0.002/0.48, p = 0.017) as independent prognostic factors of overall survival/progression-free survival.ConclusionsWith low morbidity and mortality rates, PIPAC is a safe option for palliative treatment of advanced ovarian cancer. Promising results were observed after 3 PIPAC, which did improve the peritoneal burden. However, further research is needed to evaluate the potential role of PIPAC as an independent prognostic factor

    Synthesis, Properties and Aging of ICP-CVD SiCxNy:H Films Formed from Tetramethyldisilazane

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    Amorphous hydrogenated silicon carbonitride films were synthesized on Si(100), Ge(111), and fused silica substrates using the inductively coupled plasma chemical vapor deposition technique. 1,1,3,3-tetramethyldisilazane (TMDSN) was used as a single-source precursor. The effect of the precursor’s pressure in the initial gas mixture, the substrate temperature, the plasma power, and the flow rate of nitrogen gas as an additional reagent on the film growth rate, element composition, chemical bonding, wettability of film surface, and the optical and mechanical properties of a-SiCxNy:H films was investigated. In situ diagnostic studies of the gas phase have been performed by optical emission spectroscopy during the film deposition process. The long-term stability of films was studied over a period of 375 days. Fourier-transform infrared (FTIR) and X-ray energy dispersive spectroscopy (EDX), and wettability measurements elucidated the oxidation of the SiCxNy:H films deposited using TMDSN + N2 mixture. Films obtained from a mixture with argon had high stability and maintained the stability of element composition after long-term storage in ambient air

    The Quality and Productivity of Strawberry (Fragaria × ananassa Duch.) Improved by the Inoculation of PGPR Bacillus velezensis BS89 in Field Experiments

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    Efficient plant-growth-promoting rhizobacteria (PGPR) used as biofertilizers and biological control agents are promising substitutes for minimizing the application of synthetic agrochemicals in crop production. We studied the effect of PGPR strain Bacillus velezensis BS89 alone and in combination with three forms of nitrogen fertilizers (ammonium nitrate, carbamide, and ammonium sulfate) on the productivity of two strawberry varieties in three-year field experiments. We first showed that the application of PGPR Bacillus velezensis BS89 on strawberries demonstrated the same effect as the application of nitrogen fertilizers. Use of the strain BS89 increased the chlorophyll content in plant leaves by 2.7–6.8%, and also increased the yield of berries by 6.7–36.4% for cv. Rusich and 7.5–19.3% for cv. Troitskaya depending on the form of nitrogen fertilizer. The best results in the yield of strawberry plants of the cv. Rusich were achieved in the variant BS89 + ammonium nitrate (41.9–57.4%), and the cv. Troitskaya—in the BS89 + carbamide variant (8.1–38.8%). Three-year use of strain BS89 for cv. Rusich resulted in an increase of runner’s weight by 212.1%, and also the weight of the roots by 120%, thereby significantly improving the mineral nutrition of plants. This is mainly associated with the plant growth-promoting activity of Bacillus velezensis BS89, which was able to produce a high amount of IAA—494.1 µg/mL. We believe that the PGPR strain BS89 can be successfully used for growing strawberries. However, each variety requires careful selection of the composition of nitrogen fertilizers and analysis of the compatibility of fertilizers and the PGPR strain

    Plant Development of Early-Maturing Spring Wheat (Triticum aestivum L.) under Inoculation with Bacillus sp. V2026

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    The effect of a plant growth-promoting bacterium (PGPB) Bacillus sp. V2026, a producer of indolyl-3-acetic acid (IAA) and gibberellic acid (GA), on the ontogenesis and productivity of four genotypes of early-maturing spring wheat was studied under controlled conditions. The inoculation of wheat plants with Bacillus sp. V2026 increased the levels of endogenous IAA and GA in wheat of all genotypes and the level of trans-Zeatin in Sonora 64 and Leningradskaya rannyaya cvs but decreased it in AFI177 and AFI91 ultra-early lines. Interactions between the factors “genotype” and “inoculation” were significant for IAA, GA, and trans-Zeatin concentrations in wheat shoots and roots. The inoculation increased the levels of chlorophylls and carotenoids and reduced lipid peroxidation in leaves of all genotypes. The inoculation resulted in a significant increase in grain yield (by 33–62%), a reduction in the time for passing the stages of ontogenesis (by 2–3 days), and an increase in the content of macro- and microelements and protein in the grain. Early-maturing wheat genotypes showed a different response to inoculation with the bacterium Bacillus sp. V2026. Cv. Leningradskaya rannyaya was most responsive to inoculation with Bacillus sp. V2026

    Epiphytic PGPB <i>Bacillus megaterium</i> AFI1 and <i>Paenibacillus nicotianae</i> AFI2 Improve Wheat Growth and Antioxidant Status under Ni Stress

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    The present study demonstrates the Ni toxicity-ameliorating and growth-promoting abilities of two different bacterial isolates when applied to wheat (Triticum aestivum L.) as the host plant. Two bacterial strains tolerant to Ni stress were isolated from wheat seeds and selected based on their ability to improve the germination of wheat plants; they were identified as Bacillus megaterium AFI1 and Paenibacillus nicotianae AFI2. The protective effects of these epiphytic bacteria against Ni stress were studied in model experiments with two wheat cultivars: Ni stress-tolerant Leningradskaya 6 and susceptible Chinese spring. When these isolates were used as the inoculants applied to Ni-treated wheat plants, the growth parameters and the levels of photosynthetic pigments of the two wheat cultivars both under normal and Ni-stress conditions were increased, though B. megaterium AFI1 had a more pronounced ameliorative effect on the Ni contents in plant tissues due to its synthesis of siderophores. Over the 10 days of Ni exposure, the plant growth promotion bacteria (PGPB) significantly reduced the lipid peroxidation (LPO), ascorbate peroxidase (APX), superoxide dismutase (SOD) activities and proline content in the leaves of both wheat cultivars. The PGPB also increased peroxidase (POX) activity and the levels of chlorophyll a, chlorophyll b, and carotenoids in the wheat leaves. It was concluded that B. megaterium AFI1 is an ideal candidate for bioremediation and wheat growth promotion against Ni-induced oxidative stress, as it increases photosynthetic pigment contents, induces the antioxidant defense system, and lowers Ni metal uptake

    Epiphytic PGPB Bacillus megaterium AFI1 and Paenibacillus nicotianae AFI2 Improve Wheat Growth and Antioxidant Status under Ni Stress

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    The present study demonstrates the Ni toxicity-ameliorating and growth-promoting abilities of two different bacterial isolates when applied to wheat (Triticum aestivum L.) as the host plant. Two bacterial strains tolerant to Ni stress were isolated from wheat seeds and selected based on their ability to improve the germination of wheat plants; they were identified as Bacillus megaterium AFI1 and Paenibacillus nicotianae AFI2. The protective effects of these epiphytic bacteria against Ni stress were studied in model experiments with two wheat cultivars: Ni stress-tolerant Leningradskaya 6 and susceptible Chinese spring. When these isolates were used as the inoculants applied to Ni-treated wheat plants, the growth parameters and the levels of photosynthetic pigments of the two wheat cultivars both under normal and Ni-stress conditions were increased, though B. megaterium AFI1 had a more pronounced ameliorative effect on the Ni contents in plant tissues due to its synthesis of siderophores. Over the 10 days of Ni exposure, the plant growth promotion bacteria (PGPB) significantly reduced the lipid peroxidation (LPO), ascorbate peroxidase (APX), superoxide dismutase (SOD) activities and proline content in the leaves of both wheat cultivars. The PGPB also increased peroxidase (POX) activity and the levels of chlorophyll a, chlorophyll b, and carotenoids in the wheat leaves. It was concluded that B. megaterium AFI1 is an ideal candidate for bioremediation and wheat growth promotion against Ni-induced oxidative stress, as it increases photosynthetic pigment contents, induces the antioxidant defense system, and lowers Ni metal uptake

    Ефективність підготовки студентів на заняттях фізичними вправами в вузах різних відомств

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    Purpose. To make a comparative analysis and evaluate the effectiveness of physical exercises in a technical university and departmental university of the Ministry of Internal Affairs of Russia. Material and methods. The study involved male students (1 functional group of health) of the Irkutsk National Research Technical University (Russia, n = 1380) and cadets of the East Siberian Institute of the Ministry of Internal Affairs of Russia (Russia, n = 762). Cadets studied at 1, 2 and 3 courses. The characteristics of physical preparation and the functional condition of students and cadets were analyzed. Results. During the training period, most indicators of cadets' physical preparation significantly exceed their values ​​in students. This is due to the preliminary selection of candidates for training in educational institutions of the Ministry of Internal Affairs of Russia. It is also associated with a expressed training orientation of the process of physical preparation. The dynamics of the values of the indicators of the functional condition of the body of cadets is characterized by a high price of adaptation to physical activity. This can lead to the occurrence of pre-pathological conditions and pathological processes of the cardiovascular system. Conclusions. The dynamics of the values of indicators of physical preparation of students and cadets cannot be the only objective criterion for the effectiveness of the system of their physical education. For its full assessment, it is necessary to analyze the parameters of the functional condition of the body, characterizing the reaction to physical activity. Cadets have a great adaptation to physical activity. In this case, it cannot be concluded that the physical training of cadets is more effective.Цель. Дать сравнительную характеристику и провести оценку эффективности занятий физическими упражнениями в техническом вузе и ведомственном вузе системы МВД России. Материал и методы. В исследовании приняли участие студенты мужского пола (1 функциональная группа здоровья) Иркутского национального исследовательского технического университета (Россия, n=1380) и курсанты Восточно-Сибирского института МВД России (Россия, n=762). Курсанты учились на 1, 2 и 3 курсе. Анализировались характеристики физической подготовленности и функционального состояния студентов и курсантов. Результаты. В течение периода обучения большинство показателей физической подготовленности курсантов, значительно превышают их величины у студентов. Это связано с проведением предварительного отбора кандидатов для обучения в образовательных организациях системы МВД России. Также связано с выраженной тренировочной направленностью процесса физической подготовки. Динамика значений показателей функционального состояния организма курсантов характеризуется высокой ценой адаптации к физическим нагрузкам. Это может привести к возникновению предпатологических состояний и патологических процессов сердечно-сосудистой системы. Выводы. Динамика значений показателей физической подготовленности студентов и курсантов не может выступать единственным объективным критерием эффективности системы их физического воспитания. Для ее полноценной оценки необходим анализ параметров функционального состояния организма, характеризующих реакцию на физические нагрузки. Курсанты имеют большую адаптацию к физическим нагрузкам. В данном случае нельзя сделать вывод о большей эффективности занятий по физической подготовке курсантов.Мета. Дати порівняльну характеристику і провести оцінку ефективності занять фізичними вправами в технічному вузі і відомчому виші системи МВС Росії. Матеріал і методи. У дослідженні взяли участь студенти чоловічої статі (1 функціональна група здоров'я) Іркутського національного дослідницького технічного університету (Росія, n = 1380) і курсанти Східно-Сибірського інституту МВС Росії (Росія, n = 762). Курсанти вчилися на 1, 2 і 3 курсі. Аналізувалися характеристики фізичної підготовленості та функціонального стану студентів і курсантів. Результати. Протягом періоду навчання більшість показників фізичної підготовленості курсантів, значно перевищують їх величини у студентів. Це пов'язано з проведенням попереднього відбору кандидатів для навчання в освітніх організаціях системи МВС Росії. Також пов'язано з вираженою тренувальної спрямованістю процесу фізичної підготовки. Динаміка значень показників функціонального стану організму курсантів характеризується високою ціною адаптації до фізичних навантажень. Це може привести до виникнення передпатологічних станів і патологічних процесів серцево-судинної системи. Висновки. Динаміка значень показників фізичної підготовленості студентів і курсантів не може виступати єдиним об'єктивним критерієм ефективності системи їх фізичного виховання. Для її повноцінної оцінки необхідний аналіз параметрів функціонального стану організму, що характеризують реакцію на фізичні навантаження. Курсанти мають велику адаптацію до фізичних навантажень. В даному випадку не можна зробити висновок про більшу ефективність занять з фізичної підготовки курсантів

    Bioactivity Study of the C60-L-Threonine Derivative for Potential Application in Agriculture

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    The present paper reports data on the biological activity of nanocompositions based on a C60-L-threonine (C60-Thr) derivative. These nanocompositions promote the nonspecific resistance of plants to the action of stress factors (ultraviolet radiation, pesticides, and phytopathogens). Additionally, we determined the perspectives of the C60-Thr adduct application in the cultivation of plants due to the decrease of the pesticide load on the environment. The biological study of C60-Thr revealed the plant growth-stimulating ability due to its influence on the photosynthetic apparatus activity and antioxidant properties
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