Corporate venture capital, strategic alliances, and the governance of newly public firms

We examine the effect of investments by corporate venture capitalists (CVCs) on the governance structures of venture backed IPOs. One of the main differences between CVCs and traditional venture capitalists (TVCs) is that the former often invest for strategic reasons and enter into various types of strategic alliances with their portfolio firms that last well beyond the IPO. We argue that the presence of such strategic alliances will have a significant impact on the governance structure of CVC backed firms when they go public and in the following years. Using a sample of venture backed IPOs, we evaluate several hypotheses concerning the role of CVCs in the corporate governance of newly public firms. We find that strategic CVC backed IPOs have weaker CEOs and more outsiders on the board and on the compensation committee than a carefully selected sample of matching firms. In addition, the probability of forced CEOs turnover is higher for strategic CVC backed IPOs, while at the same time these firms use staggered boards more frequently. In contrast, the governance structures of purely financial CVC backed IPO firms and their matching firms do not exhibit any significant differences.

Molecular Cloning of a Bovine Immunoglobulin Lambda Chain cDNA

A cDNA library of the bovine mammary gland constructed in pBR322 was screened by mRNA hybrid-selected translation and by differential hybridization. Several immunoglobulin (Ig) λ light-chain clones were identified and sequenced. Nucleotide sequence comparison of bovine and human Ig λ chains showed a high degree of homology for constant regions and for J regions. The amino acid (aa) sequence encoded by the constant region of the bovine Ig λ chain cDNA contains 107 aa with differences at 24 aa positions from the human Ig A chain. Three complementarity-determining regions (CDR1,2,3) characteristic of the variable region of bovine Ig λ chain cDNA can be distinguished. The bovine and human sequences display good homology in the framework region 3 (FR3) but only patches of homology throughout the FR2 region. The 5′ end of the bovine Ig λ chain cDNA fragment of clone 1-14E contains five stop codons: two in CDR1, one in FR1 and two in the hydrophobic prepeptide region. These data suggest that the Igλ mRNA of clone 1-14E is transcribed from the Vλ pseudogene

Riemann-Hilbert problem, integrability and reductions

The present paper is dedicated to integrable models with Mikhailov reduction groups $G_R \simeq \mathbb{D}_h.$ Their Lax representation allows us to prove, that their solution is equivalent to solving Riemann-Hilbert problems, whose contours depend on the realization of the $G_R$-action on the spectral parameter. Two new examples of Nonlinear Evolution Equations (NLEE) with $\mathbb{D}_h$ symmetries are presented.Comment: 19 pages, 3 figures, Dedicated to Darryl Holm's 70th birthda

STRA13 Interacts with STAT3 and Modulates Transcription of STAT3-dependent Targets

STRA13 is a pVHL-dependent bHLH transcription factor up-regulated on the mRNA level in multiple cancer cell lines and implicated recently in the regulation of immune cell homeostasis and autoimmunity. In searching for STRA13-interacting proteins with oncogenic potential by the yeast two-hybrid screening, we identified STAT3β as a STRA13-binding partner. We showed that STRA13 binds predominantly to phosphorylated (active) STAT3 α and β isoforms via its HLH and C-terminal regions. We also found that STRA13 was able to activate transcription from STAT-dependent cis-elements. Expression of endogenous STRA13 was shown to be cytokine-inducible, consistent with STRA13 involvement in STAT-dependent transcription regulation. We demonstrated that the STAT3-regulated promoter of the pro-apoptotic Fas gene was activated upon STRA13 over-expression and that co-expression of STRA13 with STAT3β or STAT3α modulated the transcriptional outcome. Forced expression of STRA13 induced apoptosis, in agreement with the STRA13 activation effect on the Fas promoter. Simultaneous expression of STRA13 and STAT3β resulted in alleviation of the STRA13 pro-apoptotic effect. Thus, for the first time, we identify STRA13 as a STAT3 partner and provide a consistent line of evidence for STRA13 involvement into regulation of apoptosis via the STAT pathways

Embryonal Antigens in Maize Caryopses: The Temporal Order of Antigen Accumulation during Embryogenesis

The sequential appearance of a specific group of embryonal antigens (EA), presumably globulins, was demonstrated in developing maize (Zea mays L.) caryopses using a double immunodiffusion test with absorption of common antigens. Cross immunoelectrophoresis was employed to follow the differential pattern of EA accumulation in the growing scutellum and embryonic axis. The transient nature of two predominant EA seems to indicate their role as specific protein reserves of embryonal tissues. Another presumably organ-specific EA was maintained in callus obtained from a 28-day-old culture of scutellum isolated from the mature non-germinated caryopsis

SETTING UP A DIGITAL LEARNING ENVIRONMENT IN A PEDAGOGICAL UNIVERSITY

This article is aimed at discovering the development particularities of the digital Russian university management system in Russia in the context of universal digitalisation, and identifying the opportunities for the development of university digital learning environment elements. The leading research method of the issue is a comparative analysis of the level of digital competences of students of professional education in Russia and the European Union member states. The authors of the article discovered the particularities of modern education transformational processes, revealed the main role of the development of information and communication technologies, determined the place of Russia in the world learning space and analysed the dynamics of the position of Russian higher educational institutions in the world university rating.Este artículo tiene como objetivo descubrir las particularidades de desarrollo del sistema digital de gestión de la universidad rusa en Rusia en el contexto de la digitalización universal, e identificar las oportunidades para el desarrollo de elementos del entorno de aprendizaje digital universitario. El principal método de investigación del tema es un análisis comparativo del nivel de competencias digitales de los estudiantes de educación profesional en Rusia y los estados miembros de la Unión Europea. Los autores del artículo descubrieron las particularidades de los procesos de transformación de la educación moderna, revelaron el papel principal del desarrollo de las tecnologías de información y comunicación, determinaron el lugar de Rusia en el espacio de aprendizaje mundial y analizaron la dinámica de la posición de las instituciones de educación superior rusas en La calificación de la universidad mundial.Este artigo tem como objetivo descobrir as particularidades de desenvolvimento do sistema de gerenciamento de universidades digitais da Rússia na Rússia no contexto da digitalização universal e identificar as oportunidades para o desenvolvimento de elementos do ambiente de aprendizado digital das universidades. O principal método de pesquisa da questão é uma análise comparativa do nível de competências digitais de estudantes de educação profissional na Rússia e nos estados membros da União Europeia. Os autores do artigo descobriram as particularidades dos processos transformacionais da educação moderna, revelaram o papel principal do desenvolvimento das tecnologias da informação e da comunicação, determinaram o lugar da Rússia no espaço de aprendizado mundial e analisaram a dinâmica da posição das instituições de ensino superior russas no país. a classificação mundial da universidade

Immunohistochemical Studies of S-100 Protein During Postnatal Ontogenesis of the Brain of Two Strains of Rats

We have studied the dynamics of the appearance of cells reacting positively with anti-S-100 protein antiserum, during postnatal neurocytogenesis in the brain of rats of two strains differing in their susceptibility to sound stimuli. The postnatal time of appearance of cells reacting positively with anti-S-100 protein antiserum was somewhat later in rats susceptible to sound-induced seizures than in sound-resistant rats. These differences concerned mainly the cerebral cortex of 12-day-old rats. By day 21 of postnatal life these differences had disappeared. In subcortical structures of the brain, S-100 protein was first found on the 4th to the 5th day of life and the rate of appearance of cells containing this protein was similar in the two strains

Synthesis of inorganic dyes based on plasmonic silver nanoparticles for the visible and infrared regions of the spectrum

The effect of various technological factors during the multistage synthesis of plasmonic silver particles in aqueous solutions on nanoparticle size, morphology, and color is studied. The synthesized suspensions are found to contain tabular silver nanoparticles of hexagonal and triangular shape. The foundations of the technology for synthesizing stable silver colloids with a high silver concentration for the visible and nearinfrared regions of the spectrum are developed

Inverse Scattering Transform for the Camassa-Holm equation

An Inverse Scattering Method is developed for the Camassa-Holm equation. As an illustration of our approach the solutions corresponding to the reflectionless potentials are explicitly constructed in terms of the scattering data. The main difference with respect to the standard Inverse Scattering Transform lies in the fact that we have a weighted spectral problem. We therefore have to develop different asymptotic expansions.Comment: 17 pages, LaTe

Robust cryogenic matched low-pass coaxial filters for quantum computing applications

Electromagnetic noise is one of the key external factors decreasing superconducting qubits coherence. Matched coaxial filters can prevent microwave and IR photons negative influence on superconducting quantum circuits. Here, we report on design and fabrication route of matched low-pass coaxial filters for noise-sensitive measurements at milliKelvin temperatures. A robust transmission coefficient with designed linear absorption (-1dB/GHz) and ultralow reflection losses less than -20 dB up to 20 GHz is achieved. We present a mathematical model for evaluating and predicting filters transmission parameters depending on their dimensions. It is experimentally approved on two filters prototypes different lengths with compound of Cu powder and Stycast commercial resin demonstrating excellent matching. The presented design and assembly route are universal for various compounds and provide high repeatability of geometrical and microwave characteristics. Finally, we demonstrate three filters with almost equal reflection and transmission characteristics in the range from 0 to 20 GHz, which is quite useful to control multiple channel superconducting quantum circuits.Comment: 5 pages, 4 figure