4,022 research outputs found
Environmentally-induced discharge transient coupling to spacecraft
The Hughes SCREENS (Space Craft Response to Environments of Space) technique was applied to generic spin and 3-axis stabilized spacecraft models. It involved the NASCAP modeling for surface charging and lumped element modeling for transients coupling into a spacecraft. A differential voltage between antenna and spun shelf of approx. 400 V and current of 12 A resulted from discharge at antenna for the spinner and approx. 3 kv and 0.3 A from a discharge at solar panels for the 3-axis stabilized Spacecraft. A typical interface circuit response was analyzed to show that the transients would couple into the Spacecraft System through ground points, which are most vulnerable. A compilation and review was performed on 15 years of available data from electron and ion current collection phenomena. Empirical models were developed to match data and compared with flight data of Pix-1 and Pix-2 mission. It was found that large space power systems would float negative and discharge if operated at or above 300 V. Several recommendations are given to improve the models and to apply them to large space systems
W-band sparse synthetic aperture for computational imaging
journal articleWe present a sparse synthetic-aperture, active imaging system at W-band (75 - 110 GHz), which uses sub-harmonic mixer modules. The system employs mechanical scanning of the receiver module position, and a fixed transmitter module. A vector network analyzer provides the back end detection. A full-wave forward model allows accurate construction of the image transfer matrix. We solve the inverse problem to reconstruct scenes using the least squares technique. We demonstrate far-field, diffraction limited imaging of 2D and 3D objects and achieve a cross-range resolution of 3 mm and a depth-range resolution of 4 mm, respectively. Furthermore, we develop an information-based metric to evaluate the performance of a given image transfer matrix for noise-limited, computational imaging systems. We use this metric to find the optimal gain of the radiating ele ment for a given range, both theoretically and experimentally in our system
Toxicological Significance of Silicon-protein Interaction
In order to understand the molecular mechanism of the toxicity of Si containing particulate air pollutants, the interaction between silicate anion and proteins was studied. On the basis of molecular sieving profile, the presence of a protein fraction capable of binding silicic acid was detected in rat lung and serum. The binding is firm being able to withstand dialysis, Si-binding by Bovine Serum Albumin (BSA) follows stoichiometric principles indicating true chemical reaction in terms of effects of pH, temperature and period of incubation. Fluorescence spectrum of the BSA-Si complex decreased with an increase in Si concentration. Effect of Si-binding on trypsin activity against albumin showed that proteins other than albumin could also interact with Si-trypsin containing silica showed distinctly low, catalytic activity against native BSA. When both the substrate and enzyme contained bound Si, the activity further reduced by 36 per cent as compared to both pure trypsin and pure BSA, clearly indicating that binding of Si with substrate or enzyme proteins can adversely effect the biological activity. Complexing with proteins is likely to play a role in pathogenesis of pneumoconiosis, elimination of dusts, formation of silicate stones in plants and animals, and possibly in the reported role of Si in nutrition, cardiovascular diseases and ageing
Mother mouse sets the circadian clock of pups
We report here the ontogeny of a circadian clock of the field mouseMus booduga expressing itself 16 days after parturition in the locomotory activity of neonate pups removed from the mother and held in continuous darkness ever since birth. Locomotion is a 'complex' activity serving such functions as foraging, exploration, and territoriality. Since these functions are not conventionally associated with neonate and altricial animals, it is of interest that this ability has such an early circadian origin. A backward extrapolation of the pups rhythm and the rhythm of the mother strongly implicate maternal synchronization. The period of the circadian rhythm of the pups shortens with age, from birth up to six months
Continuous light abolishes the maternal entrainment of the circadian activity rhythm of the pups in the field mouse
12:12-h cycles of presence and absence of mother mouse act as a 'zeitgeber' and entrain the circadian rhythm of locomotor activity in the pups ofMus booduga under continuous darkness or continuous dim light. Continuous higher illumination of 15-25 lx abolishes this impressive maternal entrainment
Spin-Hall effect and circular birefringence of a uniaxial crystal plate
The linear birefringence of uniaxial crystal plates is known since the 17th
century, and it is widely used in numerous optical setups and devices. Here we
demonstrate, both theoretically and experimentally, a fine lateral circular
birefringence of such crystal plates. This effect is a novel example of the
spin-Hall effect of light, i.e., a transverse spin-dependent shift of the
paraxial light beam transmitted through the plate. The well-known linear
birefringence and the new circular birefringence form an interesting analogy
with the Goos-H\"anchen and Imbert-Fedorov beam shifts that appear in the light
reflection at a dielectric interface. We report the experimental observation of
the effect in a remarkably simple system of a tilted half-wave plate and
polarizers using polarimetric and quantum-weak-measurement techniques for the
beam-shift measurements. In view of great recent interest in spin-orbit
interaction phenomena, our results could find applications in modern
polarization optics and nano-photonics.Comment: 16 pages, 8 figures, to appear in Optic
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Concurrent Chemoradiation for Vaginal Cancer
Background: It is not known whether the addition of chemotherapy to radiation therapy improves outcomes in primary vaginal cancer. Here, we review clinical outcomes in patients with primary vaginal cancer treated with radiation therapy (RT) or concurrent chemoradiation therapy (CRT). Methods: Seventy-one patients with primary vaginal cancer treated with definitive RT with or without concurrent chemotherapy at a single institution were identified and their records reviewed. A total of 51 patients were treated with RT alone; 20 patients were treated with CRT. Recurrences were analyzed. Overall survival (OS) and disease-free survival (DFS) rates were estimated using the Kaplan-Meier method. Cox regression analysis was performed. Results: The median age at diagnosis was 61 years (range, 18–92 years) and the median follow-up time among survivors was 3.0 years. Kaplan-Meier estimates for OS and DFS differed significantly between the RT and CRT groups (3-yr OS = 56% vs. 79%, log-rank p = 0.037; 3-yr DFS = 43% vs. 73%, log-rank p = 0.011). Twenty-three patients (45%) in the RT group had a relapse at any site compared to 3 (15%) in the CRT group (p = 0.027). With regard to the sites of first relapse, 10 patients (14%) had local only, 4 (6%) had local and regional, 9 (13%) had regional only, 1 (1%) had regional and distant, and 2 (3%) had distant only relapse. On univariate analysis, the use of concurrent chemotherapy, FIGO stage, tumor size, and date of diagnosis were significant predictors of DFS. On multivariate analysis, the use of concurrent chemotherapy remained a significant predictor of DFS (hazard ratio 0.31 (95% CI, 0.10–0.97; p = 0.04)). Conclusions: Vaginal cancer results in poor outcomes. Adequate radiation dose is essential to ensure curative management. Concurrent chemotherapy should be considered for vaginal cancer patients
Report of the Marine Protected Areas Working Group meeting, Penang, Malaysia, 11-12 February, 2014
The objectives of the workshop were to review and update Marine Protected Area (MPA) data, finalise policy briefs for each country and recommend future actions and policies for sustainable management of MPAs
Marine Managed Areas Workshop report, Penang, Malaysia, 18-19 January, 2011
Establishment of a working group of regional experts in Marine Protected Areas (MPAs); inventory and status of existing MPAs; gap analysis;establishment of common data requirements and protocols;development of a regional action plan;training and capacity building; outreach activities; proposal f0r management of existing and creation of new MPAs
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