Control of Alternaria alternata, Causal Agent of Dead (Dormant) Flower Bud Disease of Pear

Dead (dormant) flower buds of pear are an important phenomenon in pear production in the Netherlands. Vigourous or unbalanced tree growth and Pseudomonas syringae pv. syringae (P.s.s.) are mentioned as likely causes of dead flower buds. Pseudomonas syringae pv. syringae was occasionally isolated from diseased flower buds. However, Alternaria alternata was nearly always isolated from diseased buds and also often in symptomless flower buds. By identifying the causal agent of dead flower buds disease, an effective control strategy can be developed. In field trials it was proven that fungicide treatments can reduce disease incidences significantly

Genetic analysis of morningness and eveningness

We studied the influence of genetic factors on individual differences in morningness-eveningness in a sample of Dutch twin families. Data were collected from adolescent twins (mean age 17.8 yr) and their parents (mean age of fathers 48.0 yr and of mothers 46.0 yr) and a sample of older twins (mean age 46.5 yr). Scores on morningness-eveningness were rated on a 5-point scale. Parents were more morning oriented than their children, and women were more morning oriented than men. With a twin-family study, separation of genetic and environmental influences on variation in morningness-eveningness is possible. Including parents and older twins in the study makes it possible to explore generation differences in these effects. The correlation between monozygotic twins was more than twice the correlation between dizygotic twins. This indicates that genetic effects may not operate in an additive manner. Therefore, a model that included genetic dominance was explored. Biometrical model fitting showed no sex differences for the magnitude of genetic and environmental factors. The total heritability--the sum of additive and nonadditive genetic influences--for morningness-eveningness was 44% for the younger generation and 47% for the older generation. However, the genetic correlation between the generations turned out to be lower than 0.5, suggesting that different genes for morningness-eveningness are expressed in both generations

Epidemiology and effective control of Altenaria altenata, causal agent of dead (dormant) flower bud disease of pear

Dead flower buds are a common phenomenon in pear culture in The Netherlands, Belgium and Mediterranean countries. Disease cases are also reported from South America. The disease is characterized by a partial or complete necrosis of flower buds during tree dormancy. The disease progresses during winter and spring, eventually resulting in the death of most flowers and decay of buds at flowering. In The Netherlands the problem is mostly found in the main pear cultivar ‘Conference’, but cultivars such as ‘Doyenne du Comice’ and ‘Gieser Wildeman’ are also affected. Disease incidence may be as high as 80-90%. Possible causes mentioned are abiotic stresses, incompatibility between scion and cultivar, and plant pathogens and pests. Research in recent years revealed that pear growth regulation does not prevent the occurrence of dead flower buds. Also, the bacterium Pseudomonas syringae pv. syringae (P.s.s.) was commonly regarded as the causal agent of dead flower buds in pear, although the relation between P.s.s. and dead flower buds in orchards has never been proven in The Netherlands. However, the fungus Alternaria alternata was found in diseased flower buds and also often in symptomless flower buds. A linear relationship between infection rate and dead flower bud disease incidence was found. Pathogenicity tests and Koch’s postulates were carried out. It was concluded that A. alternata is the causal agent of dead (dormant) flower bud disease. A. alternata is known to cause late blight in pistachio and several diseases in fruit crops such as moldy-core in apple and brown rot in citrus. By identifying the causal agent of dead flower bud disease, an effective control strategy could be developed. In field trials it was proven that fungicide treatments can reduce disease incidence significantly

A Potential Diagnostic Approach for Foetal Long-QT Syndrome, Developed and Validated in Children

Developmen

Diagnostic accuracy of the response to the brief tachycardia provoked by standing in children suspected for long QT syndrome

BACKGROUND Adult long QT syndrome (LQTS) patients have inadequate corrected QT interval (QTc) shortening and an abnormal T-wave response to the sudden heart rate acceleration provoked by standing. In adults, this knowledge can be used to aid an LQTS diagnosis and, possibly, for risk stratification. However, data on the diagnostic value of the standing test in children are currently limited. OBJECTIVE To determine the potential value of the standing test to aid LQTS diagnostics in children. METHODS In a prospective cohort including children (= 490 ms after standing only slightly increased sensitivity (91%, 95% confidence interval [CI]: 80%-98%) and slightly decreased specificity (58%, 95% CI: 47%-70%). Sensitivity increased slightly more when T-wave abnormalities were present (94%, 95% CI: 82%-99%; specificity 53%, 95% CI: 42%-65%). When a baseline QTc >= 440 ms was accompanied by a QTc >= 490 ms and T-wave abnormalities after standing, sensitivity further increased (96%, 95% CI: 85%-99%) at the expense of a further specificity decrease (41%, 95% CI: 30%-52%). Beat-to-beat analysis showed that 30 seconds after standing, LQTS children had a greater increase in heart rate compared to controls, which was more evidently present in LQTS boys and LQTS type 1 children. CONCLUSION In children, the standing test has limited additive diagnostic value for LQTS over a baseline electrocardiogram, while T-wave abnormalities after standing also have limited additional value. The standing test for LQTS should only be used with caution in children.Developmen

Physics of rotation in stellar models

In these lecture notes, we present the equations presently used in stellar interior models in order to compute the effects of axial rotation. We discuss the hypotheses made. We suggest that the effects of rotation might play a key role at low metallicity.Comment: 32 pages, 7 figures, lectures, CNRS school, will be published by Springe

Monopole characteristics in various Abelian gauges

Renormalization group (RG) smoothing is employed on the lattice to investigate and to compare the monopole structure of the SU(2) vacuum as seen in different gauges (maximally Abelian (MAG), Polyakov loop (PG) and Laplacian gauge (LG)). Physically relevant types of monopoles (LG and MAG) are distinguished by their behavior near the deconfining phase transition. For the LG, Abelian projection reproduces well the gauge independent monopole structure encoded in an auxiliary Higgs field. Density and localization properties of monopoles, their non-Abelian action and topological charge are studied. Results are presented confirming the Abelian dominance with respect to the non-perturbative static potential for all gauges considered.Comment: 36 pages, 12 figure