Measurement of Sugar Cane Chain in Brazil

Despite the historical importance of the sugarcane business in Brazil, which is as old in the country as its colonization, it has never been "photographed in widescreen". This research on the mapping and quantification of business generated in the sugarcane chain in 2008 for the first time gives the scale of the entire sugarcane productive chain in Brazil. The sector now shows the numbers that indicate the industry's role in building the country's GDP, as well as in job creation, tax generation, and the distribution (capillary) of economic activities. By applying the method Strategic Management of Agro-Systems (GESIS), developed by the first author, Professor Marcos Fava Neves, coordinator of the Marketing & Strategic Projects and Research Center, USP (MARKESTRAT), it was found that the sugarcane sector GDP is around $28.1 billion USD, equivalent to almost 2% of the Brazilian GDP or almost all of the income generated in a year in a country like Uruguay. The majority of the industry's inputs are local, explaining its favorable trade balance situation. A series of new products has become increasingly more important and a major transformation is going on in this sector that has one of the oldest and, at the same time, most modern plants with regard to clean energy on the planet.chain mapping, chain quantification, agro-industry system, sugar cane sector, ethanol, sugar, Crop Production/Industries, Industrial Organization,

Financing Chain Associations Industry Speaks

industry associations, contribution systems, citriculture, Fundercitus, Agribusiness, Agricultural Finance, Industrial Organization, Marketing,

Publisher Correction:Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (Nature Genetics, (2020), 52, 12, (1314-1332), 10.1038/s41588-020-00713-x)

In the version of this article originally published, the e-mail address of corresponding author Patricia B. Munroe was incorrect. The error has been corrected in the HTML and PDF versions of the article

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

High blood pressure is a major risk factor for cardiovascular disease and premature death. However, there is limited knowledge on specific causal genes and pathways. To better understand the genetics of blood pressure, we genotyped 242,296 rare, low-frequency and common genetic variants in up to ~192,000 individuals, and used ~155,063 samples for independent replication. We identified 31 novel blood pressure or hypertension associated genetic regions in the general population, including three rare missense variants in RBM47, COL21A1 and RRAS with larger effects (>1.5mmHg/allele) than common variants. Multiple rare, nonsense and missense variant associations were found in A2ML1 and a low-frequency nonsense variant in ENPEP was identified. Our data extend the spectrum of allelic variation underlying blood pressure traits and hypertension, provide new insights into the pathophysiology of hypertension and indicate new targets for clinical intervention

Measurement of Sugar Cane Chain in Brazil

Despite the historical importance of the sugarcane business in Brazil, which is as old in the country as its colonization, it has never been "photographed in widescreen". This research on the mapping and quantification of business generated in the sugarcane chain in 2008 for the first time gives the scale of the entire sugarcane productive chain in Brazil. The sector now shows the numbers that indicate the industry's role in building the country's GDP, as well as in job creation, tax generation, and the distribution (capillary) of economic activities. By applying the method Strategic Management of Agro-Systems (GESIS), developed by the first author, Professor Marcos Fava Neves, coordinator of the Marketing & Strategic Projects and Research Center, USP (MARKESTRAT), it was found that the sugarcane sector GDP is around $28.1 billion USD, equivalent to almost 2% of the Brazilian GDP or almost all of the income generated in a year in a country like Uruguay. The majority of the industry's inputs are local, explaining its favorable trade balance situation. A series of new products has become increasingly more important and a major transformation is going on in this sector that has one of the oldest and, at the same time, most modern plants with regard to clean energy on the planet

Financing Chain Associations Industry Speaks

Fundecitrus, an industry association in Brazil which serves as a consortium of orange juice related industries and producers recently created a new contribution model for its organization. The model was developed based upon four pillars: (1) Benchmarking with other associations, both national and international companies. (2) Interaction with the chain community, through questionnaires, a consulting panel and workshops. (3) Formulating a collection model that was more equitable to the participating stakeholders. (4) A management and control system plan for implementing the project. The model was developed by working closely with the Fundecitrus Management Board. This research will be relevant to managers of other trade associations who are interested in restructuring their own contribution model by utilizing a process which can be replicated

Age-Dependent Association of TNFSF15/TNFSF8 Variants and Leprosy Type 1 Reaction

Submitted by Sandra Infurna ([email protected]) on 2018-02-08T13:20:26Z No. of bitstreams: 1 carolinne_marques_etal_IOC_2017.pdf: 817655 bytes, checksum: 7cf81e0844947de7820c88276120a950 (MD5)Approved for entry into archive by Sandra Infurna ([email protected]) on 2018-02-08T13:33:07Z (GMT) No. of bitstreams: 1 carolinne_marques_etal_IOC_2017.pdf: 817655 bytes, checksum: 7cf81e0844947de7820c88276120a950 (MD5)Made available in DSpace on 2018-02-08T13:33:07Z (GMT). No. of bitstreams: 1 carolinne_marques_etal_IOC_2017.pdf: 817655 bytes, checksum: 7cf81e0844947de7820c88276120a950 (MD5) Previous issue date: 2017Research Institute of the McGill University Health Centre. Program in Infectious Diseases and Immunity in Global Health. Montreal, Quebec, canada / McGill University. The McGill International TB Centre, Departments of Human Genetics and Medicine. Montreal, Quebec, Canada.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.Institut National de la Santé et de la Recherche Médicale. Laboratory of Human Genetics of Infectious Diseases. Necker Branch. Paris, France / University Paris Descartes. Imagine Institute. Paris, France / Rockefeller University. Giles Laboratory of Human Genetics of Infectious Diseases. Rockefeller Branch. New York, USA.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.Research Institute of the McGill University Health Centre. Program in Infectious Diseases and Immunity in Global Health. Montreal, Quebec, canada / McGill University. The McGill International TB Centre, Departments of Human Genetics and Medicine. Montreal, Quebec, Canada / McGill University. Deparment of Medicine. Montreal, QC, Canada.A current major challenge in leprosy control is the prevention of permanent disabilities. Host pathological inflammatory responses termed type 1 reaction (T1R) are a leading cause of nerve damage for leprosy patients. The environmental or inherited factors that predispose leprosy cases to undergo T1R are not known. However, studies have shown an important contribution of host genetics for susceptibility to T1R. We have previously identified variants encompassing the TNFSF15/TNFSF8 genes as T1R risk factors in a Vietnamese sample and replicated this association in a Brazilian sample. However, we failed to validate in Brazilian patients the strong association of TNFSF15/TNFSF8 markers rs6478108 and rs7863183 with T1R that we had observed in Vietnamese patients. Here, we investigated if the lack of validation of these variants was due to age-dependent effects on association using four independent population samples, two from Brazil and two from Vietnam. In the combined analysis across the four samples, we observed a strong association of the TNFSF15/TNFSF8 variants rs6478108, rs7863183, and rs3181348 with T1R (pcombined = 1.5E-05, pcombined = 1.8E-05, and pcombined = 6.5E-06, respectively). However, the association of rs6478108 with T1R was more pronounced in leprosy cases under 30 years of age compared to the global sample [odds ratio (OR) = 1.95, 95% confidence interval (CI) = 1.54-2.46, pcombined = 2.5E-08 versus OR = 1.46, 95% CI = 1.23-1.73, pcombined = 1.5E-05]. A multivariable analysis indicated that the association of rs6478108 with T1R was independent of either rs7863183 or rs3181348. These three variants are known regulators of the TNFSF8 gene transcription level in multiple tissues. The age dependency of association of rs6478108 and T1R suggests that the genetic control of gene expression varies across the human life span

Analyse du secteur énergétique sucrière brésilien à travers la planification stratégique

A pesar de la importancia económica de la caña de azúcar, Brasil no contaba con un balance integral de la cadena productiva. Este estudio tiene por objetivo el mapeo, cuantificación y formulación de estrategias para el sector sucroenergético, mediante la aplicación de Método de Planeamiento y Gestión Estratégica de Sistemas Agroindustriales (GESis). El período de análisis fue el año 2008. Para su desarrollo fueron identificados y cuantificados todos los eslabones que componen el sistema agroindustrial, a partir de levantamiento de información secundaria y entrevistas a ejecutivos, investigadores, instituciones y organizaciones sectoriales. Posteriormente se efectuaron las estimaciones de ventas y movimientos financieros. Entre los resultados generados se estimó un PIB sectorial ascendente a USD 28,15 billones en el 2008 -equivalentes a 1,5% del PIB brasileño-, con un nivel de empleos de 4,29 millones, considerando puestos directos e indirectos. Además, se identificó que el crecimiento del sector depende de proyectos estratégicos vinculados a áreas como investigación e innovación, distribución y logística, coordinación y adecuación institucional, así como de comunicación y capacitació[email protected]@[email protected]@[email protected]@markestrat.orgsemestralDespite the importance of sugarcane production, Brazil did not have a full figure of the production chain. This study aims to map and to quantify the chain and to formulate strategies for the sugarcane industry through the application of the Method of Strategic Planning and Management of Agroindustrial Systems (GESis). The study period is the year 2008. In developing this work, all links that make up the agroindustrial system were identified and quantified, through the collection of secondary information and interviews with executives, researchers, institutions and sector organizations. Then the sales and financial amounts were estimated. Among the results, it was found that the industry generated 28.15 billion USD, equivalent to 1.5% of national GDP, and 4.29 million direct and indirect jobs. It was also identified that the industry’s growth depends on strategic projects related to areas such as research and innovation, distribution and logistics, coordination and institutional adjustment, communication and training.Malgré l’importance économique de la canne à sucre, le Brésil ne disposait pas d’un bilan intégral de la chaîne productive. Cette étude vise à clarifier la carte, via la quantification et la formulation des stratégies pour le secteur sucrière, au moyen de l’application de Méthode de Planification et la Gestion Stratégique de Systèmes Agroindustriels (GESis). La période d’analyse a été le 2008. Pour son développement, ils ont été identifiés et quantifiés, tous les chaînons qui composent le système agroindustriel, à partir d’une levée d’information secondaire et tu as une entrevue aux exécutifs, des enquêteurs, des institutions et des organisations sectorielles. Plus tard, les estimations des ventes et des opérations financières ont été faites. Parmi les résultats obtenus, du PIB sectoriel ascendant a été estimé à USD 28,15 milliards en 2008 équivalent à 1,5% du PIB du Brésil, avec un niveau d’emplois équivalent à 4,29 millions, compte tenu des emplois directs et indirects. En outre, nous avons constaté que la croissance du secteur dépend des projets stratégiques liés à des domaines tels que la recherche et l’innovation, plus la distribution et la logistique, la coordination et la adéquation institutionnelle, ainsi que la communication et l’habilitation