7 research outputs found
Sentenced to Pretrial Detention: A Study of Bail Decisions and Outcomes
Previous research on bail practices has shown that both legal factors, such as offense severity and prior criminal record, and demographic factors such as race and age, exert a strong influence on bail decisions and outcomes. Using a novel application of Knowledge Discovery statistical methods, Bayesian probability analytics, this study utilized a sample of (n = 975) cases collected by New JerseyÕs Criminal Disposition Commission, followed from arrest through disposition, to examine bail decisions made by judges and subsequent bail outcomes, i.e., whether defendant was able to meet financial bail requirements to secure release from jail. We found the following: Black and Hispanic defendants are more likely than their white counterparts to have to pay a financial bail requirement; modest differences between races with regards to bail amount set by the court; and that minority defendants, and especially Hispanic defendants, are at a disadvantage when it comes to being able to post bail and they are therefore much more likely than their white counterparts to be held in pretrial detention
Patterns of radiotherapy practice for pancreatic cancer: Results of the Gastrointestinal Radiation Oncology Study Group multi-institutional survey
No information is currently available regarding pancreatic cancer (PC) pattern of care in Italy. In the present study, a nationwide survey using a questionnaire was performed to enquire the local standards for PC diagnosis and radiotherapy treatment. Fifty-seven percent of 140 Italian centres completed questionnaire. The main causes of no radiotherapy indication were poor general condition (45%) and lack of guidelines (25%). Physicians (38%) employed neoadjuvant therapy in locally advanced PC patients, while in other centres (62%) adjuvant chemoradiation was administered. Adjuvant gemcitabine-based chemotherapy was selected as the treatment of choice by 59% of centres. Patients were treated mostly with doses of 50-54.9 Gy on the tumour (or bed) plus lymph nodes. A 3D-CRT technique was used in 81.2% of centres, while IMRT and IGRT were available in 61.2 and 48.7% of cases, respectively. Extensive variation exists with regard to patterns of care for PC in Italy. Nevertheless, cooperative studies emerging from this survey appeared beneficial
No benefit of adjuvant Fluorouracil Leucovorin chemotherapy after neoadjuvant chemoradiotherapy in locally advanced cancer of the rectum (LARC): Long term results of a randomized trial (I-CNR-RT)
To evaluate the effect of adjuvant chemotherapy (ACT) in locally advanced rectal cancer (LARC) after neoadjuvant chemoradiation (NACT-RT). The study was funded by the Italian National Research Council (CNR)
Selection of appropriate end-points (pCR vs 2yDFS) for tailoring treatments with prediction models in locally advanced rectal cancer
Personalized treatments based on predictions for patient outcome require early characterization of a rectal cancer patient's sensitivity to treatment. This study has two aims: (1) identify the main patterns of recurrence and response to the treatments (2) evaluate pathologic complete response (pCR) and two-year disease-free survival (2yDFS) for overall survival (OS) and their potential to be relevant intermediate endpoints to predict