The case of muddled units in temporal discounting

While parameters are crucial components of cognitive models, relatively little importance has been given to their units. We show that this has lead to some parameters to be contaminated, introducing an artifactual correlation between them. We also show that this has led to the illegal comparison of parameters with different units of measurement – this may invalidate parameter comparisons across participants, conditions, groups, or studies. We demonstrate that this problem affects two related models: Stevens' power law and Rachlin's delay discounting model. We show that it may even affect models which superficially avoid the incompatible units problem, such as hyperbolic discounting. We present simulation results to demonstrate the extent of the issues caused by the muddled units problem. We offer solutions in order to avoid the problem in the future or to aid in re-interpreting existing datasets

Temporal discounting does not influence body mass index

The prevalence of obesity has driven searches for cognitive or behavioural economic factors related to Body Mass Index (BMI). One candidate is delay discounting: those who prefer smaller sooner rewards over larger but later rewards are hypothesised to have higher BMI. The findings in the literature are mixed however, with meta analyses suggesting only a very small correlation between discounting and BMI. Here we present novel empirical data (N = 381) and Bayesian analyses which suggest no such relationship between discounting of either monetary or weight loss rewards and BMI. We also find evidence against our novel proposal that discounting moderates the rate of BMI gain over time. We also present our data in the context of a random effects Bayesian meta-analytical result which does suggest the presence of a small correlation overall. The strength of the correlation is so weak (2.25% shared variance) that its practical significance may be minor to non existent. However because we found decisive evidence for unaccounted for study-level variance, due to study heterogeneity, we argue that we should treat such meta-analytic correlations with extreme caution. While the relationship between discounting and health outcomes such as BMI remain theoretically appealing, our empirical and meta-analytic results suggest we should be cautious in inferring a correlational, let alone a causal, role for discounting processes in driving BMI or moderating BMI gain with age

The Effects of Health-Promoting Signs Encouraging Stair Use in Parking Structures

This research study aims to promote physical activity by encouraging stair use rather than elevators using persuasive point-of-choice prompts. The current investigation is comprised of two sub-studies: pilot testing, which we have completed; and the main study, which will be conducted in the fall. While most studies in this area use observation to count pedestrian traffic, a novel component of the current research is that we will use a pressure mat to measure stair and elevator use. As such, before completing the main study, we completed two pilot studies to test the feasibility of the mat technology and the messaging of the persuasive prompts. We researched the type of mat that would be ideal for recording pedestrian traffic and considered features such as wired/wireless, battery-powered, open-switch, minimal threshold activation, and high-frequency recording. We completed various trials to determine the validity and accuracy of the mats in different settings and situations and the results of this analysis will be discussed. Additionally, the results from the survey conducted to evaluate potential messages on the point-of-choice prompts will also be detailed. Within this survey, message categories were narrowed to motivational/encouraging and nudging/humor messages. The survey was administered in Chapman University classes and students’ responses to several sample messages in each of these categories were compared via a series of six, semantic differential adjectives, rated on seven-point scales. Qualitative feedback on an open-ended question after each message was also solicited. The highest rated messages will be used in the main study. There are three key components to the main study, which we will complete in the fall: 1) objectively measure stair and elevator use for two weeks; 2) introduce point-of-choice prompts and measure stair and elevator use for two weeks; 3) remove signs and continue recording for an additional two weeks to observe potential effects

Functional reconstruction of the glenoid fossa utilizing a pedicled temporal osteomuscular flap

Current techniques in management of end stage pathology of the temporomandibular joint (TMJ) include the use of alloplastic joint reconstruction. A polyethylene glenoid fossa prosthesis is a necessity of this treatment as it provides a stable platform for function of the metal alloy condylar head. Additionally, the fossa prosthesis limits superior and posterior movement of the reconstructed joint which prevents complications such as migration of the condylar prosthesis into the middle cranial fossa and ear, ankylosis, and pain. When a pathologic process affects the glenoid fossa alone, alloplastic joint reconstruction becomes a less desirable treatment option. Lack of osseous structure along the temporal bone and zygomatic arch can impact the surgeon\u27s ability to fixate a glenoid fossa prosthesis. Additionally, resection of an uninvolved condylar head in situations where there is no advanced pathology would provide a functional solution, but may be overly aggressive and potentially unnecessary. The following is our experience with utilizing a pedicled temporal osteomuscular flap to reconstruct an acquired defect of the glenoid fossa in a 42-year-old male with a diffuse-type tenosynovial giant cell tumor. In this case the mandibular condyle was not affected by the pathology

An international landmine telehealth symposium between Hawaii and Thailand using an Internet2 and multi-protocol videoconferencing bridge.

An international telehealth symposium was conducted between healthcare institutions in Hawaii and Thailand using a combination of Asynchronous Transfer Mode, and Internet2 connectivity. Military and civilian experts exchanged information on the acute and rehabilitative care of landmine victims in Southeast Asia. Videoconferencing can promote civil-military cooperation in healthcare fields that have multiple international stakeholders

Neutrophilia and NETopathy as Key Pathologic Drivers of Progressive Lung Impairment in Patients With COVID-19

There is an urgent need for new therapeutic strategies to contain the spread of the novel coronavirus disease 2019 (COVID-19) and to curtail its most severe complications. Severely ill patients experience pathologic manifestations of acute respiratory distress syndrome (ARDS), and clinical reports demonstrate striking neutrophilia, elevated levels of multiple cytokines, and an exaggerated inflammatory response in fatal COVID-19. Mechanical respirator devices are the most widely applied therapy for ARDS in COVID-19, yet mechanical ventilation achieves strikingly poor survival. Many patients, who recover, experience impaired cognition or physical disability. In this review, we argue the need to develop therapies aimed at inhibiting neutrophil recruitment, activation, degranulation, and neutrophil extracellular trap (NET) release. Moreover, we suggest that currently available pharmacologic approaches should be tested as treatments for ARDS in COVID-19. In our view, targeting host-mediated immunopathology holds promise to alleviate progressive pathologic complications of ARDS and reduce morbidities and mortalities in severely ill patients with COVID-19

New Sensing Platforms for Explosives, Nerve Agents, and Raionucleotides

The purpose of this project was to build on successful past work synthesizing new families of materials and apply these to biological, chemical, and radiological detection. Our primary objectives were to exploit the fluorescence and conductivity properties of metal nanowires and the mechanical and conductivity properties of polymeric helicenes to form prototype sensors that can improve WMD proliferation detection capabilities. We focused on the following tasks: (1) Synthesis of polymeric helicenes and metal nanowires; (2) Processing materials; (3) Characterization material response; and (4) Fabrication sensor devices