Emergence of Lumpy Pox Virus and Their Preventive Measures: A Global Livestock Threat

In the last few years viral disease not only affect the human but also the other life on this planet and result epidemic condition at global level. The highly transmissible viral disease called Lumpy skin disease (LSD) spread in sequential manner at worldwide level affecting the cattle or dairy animals of caprine, ovine and bovine family. The highly mutational efficiency of this viral strains affects the large-scale population and still no effective cure for it. Different vaccines designed at national and international level as a preventive measure to overcome the reoccurrence of this virus e.g., Bovivax-LSD™, Lumpivax™, Poxvac™, Lumpi-ProVacInd. However, still the mortality of LSD are low, not affect humans but emergence of the mutational variants demands novel vaccines

Studies on the Analgesic Potential of leaf Extracts of Allium humile on Swiss albino mice

Allium humile is a medicinal plant found at the Alpine Himalayas of Uttarakhand at altitute of 2500-3000 meters height of sea level. In India, Allium humile, is used by local people as a spice and in ethano-medicine. In the present study, Allium humile leaves were explored for their analgesic potential on experimental model and compared to standard drugs. Allium humile at the doses of 100 mg/kg and aspirin 25 mg/kg exhibited significant (p>0.05) inhibition of the control writhes at the rate of 64.25%, 44.54%, 44.54% and 59.89% respectively when compared to that of control. Thus, methanolic extract of the plant can be fully explored for its analgesic potential which has not been reported so far. The plant extract showed a relative low toxicity hence justifies the folkloric use of plant by the local people in Western Himalayan region for curing inflammation and painful conditions

Micropropagation And Antimicrobial Activity Of Callicarpa Macrophylla (Priyangu) Against Medically Important Pathogens

Callicarpa macrophylla (Priyangu) a medicinally important plant, represents a class of herbal drug with very strong conceptual and traditional base. In present study extract of leaf, stem showed less antimicrobial activity than seed. They showed antimicrobial activity against three bacterial strains Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas and three fungal Strains Aspergillus fumigatous, Rhizopus oryzae and Aspergillus awamori. Maximum activity was observed in ethanol extract of leaf and stem, Methanol extracts of seed. Phytochemical analysis of the plant extract revealed the presence of phenol, reducing sugar, coumarin and saponins.  Micropropogation of C.macrophylla was done using stem as a explant material on MS and Woody media. Which revealed that woody media containing BAP (6-amino benzyl purine) NAA(α-napthaleneacetic acid) gave maximum proliferation  response in comparison to MS media. Plant extract (leave, stem and seed) have provide protection against RBC haemolysis and protein denaturation may act as anti-arthritic agent. We propose antiarthritic and antimicrobial activity of C.macrophylla

Emerging Threats In Aquaculture: Bibliometric Analysis Of Aeromonas Sps. As An Emerging Pathogen

The concern regarding emerging diseases in aquaculture has received considerable global interest. This research focuses on the recent emergence of Aeromonads as a possible zoonotic pathogen that can impact both human and aquatic organisms. Therefore, it is crucial to evaluate the current state of this issue. Bibliometric analysis is employed to evaluate the prevalence of Aeromonas in the field of aquaculture during the period spanning from 2004 to 2023. The investigation was performed with the VOSviewer software and the Dimension database. The present study investigates the patterns of publishing output and global collaboration throughout the last ten years. The results demonstrate a substantial and steady rise in the quantity of scholarly articles, accompanied by a noteworthy degree of collaboration among academics hailing from various nations.  This research investigates the global distribution of scholarly articles, with a specific emphasis on the countries of China and India, which have the highest levels of representation. The Chinese Academy of Fishery Science has attained the most substantial publication output among academic institutes. This study also examines the prominent academic journals, specifically Fish & Shellfish Immunology, Aquaculture, and Aquaculture Research, which serve as crucial platforms for the dissemination of scholarly informatio

Assessment of Genetic Fidelity of in vitro Raised Plants in Swertia chirayita through ISSR, RAPD analysis and Peroxidase Profiling during Organogenesis

ABSTRACT An efficient in vitro regeneration protocol for medicinally important herb Swertia chirayita was developed and the genetic fidelity was assessed using RAPD and ISSR markers. The best shoot regeneration was observed on MS basal supplemented with 1.0 mg/L Benzyl amino purine (BAP) in combination with Indole-3-acetic acid (IAA) (0.5 mg/L) that resulted in the increase by multiplication rate (7.65) with an average of 33.33 numbers of shoots and average shoot length of 2.70 cm. It was further enhanced by the addition of adenine sulfate (0.007%) that resulted in an average of 42 shoots per clum with 4.13 cm of average shoot length and the increase in multiplication fold to 9.75 that further resulted in the reduced use of other cytokinins and auxins. The rooting was nearly 100 % on 1/4 MS augmented with 1.0 mg/L Indole butyric acid with maximum average root length of 5.1cm. Plantlets were successfully acclimatized with 85-90 % survival rate. Ascorbate peroxidase activity increased with the maximum activity during the shoot multiplication. Clonal fidelity has been checked by two marker systems ISSR and RAPD and regenerated plants showed high clonal fidelity

<i style="mso-bidi-font-style:normal"><span style="font-size:13.0pt;mso-bidi-font-size: 12.0pt">In vitro</span></i><span style="font-size:13.0pt;mso-bidi-font-size: 12.0pt"> antimicrobial activity of aerial parts extracts of <i style="mso-bidi-font-style:normal">Aconitum heterophyllum</i> Wall.<span style="mso-bidi-font-style:italic"> ex Royle </span></span>

504-507Antimicrobial activity of extracts of aerial parts of the plant samples of Aconitum heterophyllum Wall. ex Royle was evaluated against different bacterial and fungal strains. It was observed that methanolic extract (50 mg/well) was the most potent extract which showed significant inhibition of the growth of Gram positive bacteria, Staphylococcus aureus and Bacillus subtilis. Antifungal activity was shown by two extracts against Candida albicans and Aspergillus flavus. Methanolic extract showed considerable antifungal activity while feeble antifungal activity was obtained with ethyl acetate extract even at higher concentrations. </span