An unusual case of mediastinal mass in a child presenting with pneumomediastinum and air dissection in soft tissues

Pneumomediastinum and subcutaneous emphysema can occur due to various reasons but spontaneous occurrence is rare. This rare condition can occur due to a number of traumatic and non-traumatic causes. Neoplastic lesions causing pneumomediastinum are exceedingly rare. We present such a case in a child where mediastinal mass caused non-traumatic pneumomediastinum, pneumopericardium, subcutaneous and retroperitoneal emphysema. To the extent of our knowledge, this is the first reported case of mediastinal mass resulting in spontaneous air leak

A rare case of Herlyn-Werner-Wunderlich syndrome-with pregnancy

Herlyn-Werner-Wunderlich syndrome also known as uterus didelphys with obstructing hemivaginal septum and ipsilateral renal agenesis (OHVIRA) is a very rare syndrome with only a few case reported. A female patient referred to our hospital with retention of urine revealed uterus didelphys with 8 weeks gestation sac in the left moiety and hematometra and hematocolpous in the right moiety with absent right kidney. Diagnosing this syndrome at an early stage is important to prevent the complications in these patients

An unusual case of septate uterus with double cervix and longitudinal vaginal septumâwith pregnancy

Various theories and classification systems have been proposed from time to time, to understand the embryology of the female genital system. Even then at times we come across something different, something new, which again questions our understanding of this subject matter and the theories which are most accepted worldwide. Mullerian anomalies result from the improper development and fusion of the embryological mullerian ducts. It is generally considered to occur in less than 5% of women. Here we present a rare and interesting case of a young female having septate uterus with double cervix and a longitudinal vaginal septum with pregnancy. Keywords: Embryology, Septate uterus, Double cervix, Longitudinal vaginal septu

Computer-Aided Design of Energetic Tris(tetrazolyl)amine Derivatives and Salts

New derivatives of 5,5′,5″-tris­(tetrazolyl)­amine (H₃tta) are designed by replacing N–H with N–NO₂ and N–OH groups. Two H₃tta derivatives (<b>B</b> and <b>F</b>) were selected for the design of 1:1 (cation:anion) energetic salts. Their heats of formation (HOF) and densities were predicted and combined to estimate the velocities of detonation (VOD) and detonation pressures (DP). Impact sensitivity of H₃tta compounds containing nitramine functionality was assessed using <i>h</i>₅₀, free space in a crystal lattice, and heats of detonation (<i>Q</i>). The calculated explosive power index about picric acid showed that most of the H₃tta compounds and salts can be used as potential energetic materials. Those compounds and salts were found to exhibit superior detonation performance when compared with RDX and HMX. According to our results, newly designed H₃tta derivatives may be used to develop high-performance energetic materials with lower sensitivity

A novel lineage of Ceftriaxone-resistant Salmonella Typhi from India that is closely related to XDR S. Typhi found in Pakistan

Two MDR Salmonella Typhi isolates from India were found by whole genome sequencing to be closely related to the 2016 XDR S. Typhi outbreak strain from Pakistan. The Indian isolates have no chromosomal antimicrobial resistance cassette but carry the IncY plasmid p60006. Both isolates are susceptible to chloramphenicol, azithromycin, and carbapenems