मोहन राकेश के गद्य - साहित्य का तात्विक अनुशीलन

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Risk factors for neonatal hyperbilirubinemia: a case control study

Background: Neonatal Hyperbilirubinemia is one of the most common reasons for NICU admissions. The frequency of neonatal jaundice has been on an increase since the last decade. Is the increase due to changes in obstetric practice or drugs? There is no definite reason. This study was undertaken to find out any obstetric characteristics which may contribute to the development of Neonatal Hyperbilirubinemia and which is modifiable.Methods: Record review data from 140 singleton deliveries at the Institute of Maternal & Child Health ,Govt. Medical College, Kozhikode, Kerala were analyzed to determine the relationship between neonatal hyperbilirubinemia (>10mg/dl) and maternal characteristics. Confounding variables were controlled by multiple logistic regression analysis.Results: There was statistically significant relationship between hyperbilirubinemia and LBW, preterm delivery, PPROM, breast feeding, neonatal infection, instrumental delivery and presence of GDM and IUGR.Conclusions: By identifying these obstetric characteristics, we may be able to modify them and reduce the need for NICU admissions for Neonatal Hyperbilirubinemia

ROLE OF MATRA BASTI (ENEMA) OVER ABHYANGA (MASSAGE) AND SWEDA (SUDATION) IN REDUCING SPASTICITY IN CEREBRAL PALSY WITH SUDDHA BALA TAILA-A RANDOMIZED COMPARATIVE CLINICAL STUDY

Objective of the study was to assess the efficacy of Matra basti (enema) over Abhyanga (massage) and Sweda (sudation) in reducing spasticity in cerebral palsy. Study was carried out in IPD, Department of Kaumarbhritya, KLEs Shri BMK Ayurved Mahavidyalaya, Shahapur, Belgaum, Karnataka; India.30 children fulfilling diagnostic criteria between the age group of 2-12 years were included and enrolled as per computer generated block randomization into 2 groups of 15 children in each group. Group A was administered with Matra basti (enema) after local Abhyanga (massage) with Suddha bala taila and local Swedana (sudation) with Nadi sweda (type of sudation) method for a duration of 15 days. In group B spastic children were treated with Sarvanga Abhyanga (massage all over body) followed by plain Nadi sweda with Suddha bala taila. Follow up was done on 30th and 45th day of treatment. Both the procedures were helpful in reducing spasticity. Matra basti (enema) is more effective in treating the spasticity of cerebral palsy as compared to Abhyanga (massage) and Sweda, whereas Abhyanga (massage) and Sweda (sudation) is effective in treating fine motor functions. Suddha Bala taila is effective in treating Ekanga vata (monoplegia), Pakshaghata (diplegia) and other related Vata Vyadhi (neurological disorders) as attributed to its Rogaghnata (disease). Thus the procedures are effecting in reducing spasticity

Synthesis of a New Series of Quinolinoxymethylcoumarins as Potent Anticancer Agents

4-Bromomethylcoumarins (1a-f) were reacted with 8-hydroxyquinoline to yield quinolinoxymethylcoumarins (2a-f). The structure of all the synthesized compounds were confirmed by spectral studies and screened for their anticancer activities against Dalton’s Ascitic lymphoma (DAL) and Ehrlich Ascites Carcinoma (EAC) cell lines.  Out of these, compound (2b) (R = 6-OMe) was found to be the most potent cytotoxic compound against DAL and EAC cell lines.           

Probing the physiology of ASH neuron in Caenorhabditis elegans using electric current stimulation

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/98694/1/ApplPhysLett_99_053702.pd

An integrated circuit/architecture approach to reducing leakage in deep-submicron high-performance I-caches

Deep-submicron CMOS designs maintain high transistor switching speeds by scaling down the supply voltage and proportionately, reducing the transistor threshold voltage. Lowering the threshold voltage increases leakage energy dissipation due to subthreshold leakage current even when the transistor is for switching. Estimates suggest a five- fold increase in leakage energy in every future generation. In modern microarchirectures, much of the leakage energy is dissipated in large on-chip cache memory structures with high transistor densities. While cache utilization varies both within and across applications, modern cache designs are fixed in size resulting in transistor leakage inefficiencies. This paper explores an integrated architectural and circuit level approach to reducing leakage energy in instruction caches (i-caches). At the architectural level, we propose the Dynamically Resizable i- cache (DRI i-cache), a novel i-cache design that dynamically resizes and adapts to an application's required size. At the circuit-level, we use gated-Vdd, a mechanism that effectively turns of the supply voltage to, and eliminates leakage in, the SRAM cells in a DRI i-cache's unused sections. Architectural and circuit-level simulation results indicate that a DRI i-cache successfully and robust exploits the cache size variability both within and across applications. Compared to a conventional i-cache using an aggressively-scaled threshold voltage a 64K DRI i-cache reduces on average both the leakage energy-delay product and cache size 62%, with less than 4% impact on execution tim