Experimental Studies on Abrasive Water Jet Cutting of Nano SiC Particles Filled Hybrid Basalt-Glass Fibre-Reinforced Epoxy Composites

Abrasive water jet machining (AWJM) is extensively beneficial in machining materials that are hard to cut. This investigation deals with AWJM of Nano SiC filled Epoxy reinforced with basalt-glass fiber hybrid composite. The composite is prepared by compression moulding technique. Experimental trails are performed to evaluate the impact of every process parameter on the responses i.e., surface roughness (Ra) and Material Removal Rate (MRR). The experiments are conducted by changing the standoff distance (SD), traverse speed (TS) and water pressure. The performance of the conducted experiment is analysed using a Swarm intelligence algorithm. Surface roughness and MRR are maximized by using the combination of optimum process parameter levels of 9.72 mm/min speed, 5.78 mm stand-off distance and 553 MPa jet pressure. Scanning Electron Microscopic (SEM) images are employed in detecting the morphology of machined surface and confirmed the presence of voids and fibre pull-out

Sexually transmitted infections among men who have sex with men: a retrospective study in a tertiary care hospital

Background: Men who have sex with Men (MSM) have a higher prevalence of HIV and other sexually transmitted infections (STI) than the heterosexual men. In India, NACP recommendations to reduce HIV prevalence among MSM include early detection of HIV and other STI by screening and treatment. We conducted a study of STIs among MSM attending our OPD. The aim of the study was to assess the prevalence of STIs in MSM attending our OPD.Methods: 1215 MSM among 9008 patients who attended our OPD between June 2015 and May 2016 were included in the study. Detailed history was taken and clinical examination carried out. Urethral discharge and urine samples were tested for Gonococcal infection. Smears from ulcers were tested for Syphilis, Chancroid, Herpes and Donovanosis. Serum samples were tested for HIV and other STIs like Syphilis and Herpes.Results: Among 1215 MSMs, 55 (4.5%) tested positive for VDRL and TPHA and 33 (2.7%) tested positive for HIV. 24 (2%) had urethritis (10 GU and 14 NGU), 15 (1.25%) had Balanophosthitis, 12 (1%) had genital herpes, 9 (0.75%) had genital scabies, 6 (0.5%) had Genital Wart and 2 (0.16%) had Molluscum contagiosum. Prevalence of these STIs were far higher in MSMs than in heterosexual men.Conclusions: This study highlights the higher prevalence of STIs among MSMs and the need for early intervention and treatment in this high-risk population

An observational study on dapagliflozin as an add-on therapy in type-2 diabetes mellitus patients in a tertiary care teaching hospital

Background: Diabetes mellitus is one of the prevalent morbid conditions all over the world and no exception for India. Day by day, increase in its prevalence is attributed to lifestyle derangements. To treat this condition many drugs and treatment modalities are developed. Dapagliflozin is an oral antidiabetic drug which acts by sodium-glucose cotransport-2 (SGLT-2) inhibition. Its effectiveness seen in type-2 diabetes mellitus makes it an option for Add-On therapy. Methods: This study is a retrospective observational study conducted at tertiary care hospital, GGH, Kurnool. The study proposal has been reviewed and approved by institutional ethics committee. All adult diabetic patients who were prescribed Dapagliflozin during the period of January 2021 to February 2022, total 45 were included in the study. FBG, HbA1c collected through hospital records from General Medicine and Endocrinology. Patients who stopped drug before 3 months period were excluded. Results: Administration of dapagliflozin as an add-on therapy was found 26.63% decrease in base line mean FBG 184 mg/dl to 135 mg/dl after 3mnoths which is significant (p=0.001). Mean HbA1c significantly reduced by 0.96 percentage point after 3 months (p=0.001). Dapagliflozin effectively reduced the FBG and HbA1c when used in combination with other OHAs or insulin within 3 months. Conclusions: Dapagliflozin as an add-on therapy significantly reduced the HbA1c level and fasting blood glucose of Type-2DM patients, in a 3-month treatment period. Due to the frequency of Genitourinary tract infections, caution is indicated while treating the patients

PEComa of the lung

Perivascular epithelioid cell tumor (PEComa), also called clear cell \u2032sugar\u2032 tumor of the lung, is a rare benign tumor arising from perivascular epithelioid cells (PECs). We report a case of a 15-year-old boy who presented with right lower lobe lesion which turned out to be a clear cell tumor of the lung. An [18F]-fluoro-2-deoxy-D-glucose (FDG) - positron emission tomography (PET) scan revealed mild FDG uptake in the lung lesion (SUV< 1) with no active uptake elsewhere in the body. We discuss the clinical, radiologic and immunohistochemical features of clear cell \u2032sugar\u2032 tumor of lung and compare them with published literature

Sustainable Grinding Performances of Nano-Sic Reinforced Al Matrix Composites under MQL: An Integrated Box–Behnken Design Coupled with Artificial Bee Colony (ABC) Algorithm

The presence of abrasive particles in ceramic reinforced composite materials makes the machining complicated by generating friction at elevated temperatures. Lubricants can be used to prohibit the hazard of higher temperatures. This research work is focused on examining the effects of lubricants on the grinding performances of Al matrix composites reinforced with nano-SiC particles under minimum quantity lubrication (MQL). A cylindrical grinding machine is used to perform the grinding experiments by employing a Box–Behnken design. Multiple performances, such as surface roughness, grinding forces and temperature, are optimized by considering the depth of cut, speed of the workpiece, wheel speed and wt % of nano-SiC using response surface methodology (RSM)-based artificial bee colony (ABC) algorithm. Atomic force microscope (AFM) and scanning electron microscopy (SEM) are used to observe the morphologies of the machined surfaces and the wheel

PEComa of the lung

Perivascular epithelioid cell tumor (PEComa), also called clear cell ′sugar′ tumor of the lung, is a rare benign tumor arising from perivascular epithelioid cells (PECs). We report a case of a 15-year-old boy who presented with right lower lobe lesion which turned out to be a clear cell tumor of the lung. An [18F]-fluoro-2-deoxy-D-glucose (FDG) - positron emission tomography (PET) scan revealed mild FDG uptake in the lung lesion (SUV< 1) with no active uptake elsewhere in the body. We discuss the clinical, radiologic and immunohistochemical features of clear cell ′sugar′ tumor of lung and compare them with published literature