6 research outputs found
Ehlers-Danlos syndrome
Ehlers-Danlos syndrome (EDS) is a generalized disorder of one element of connective tissue manifesting clinically by fragility and hyperelasticity of the skin and joint laxity. It is a hereditary disorder, the inheritance being usually autosomal dominant with low penetrance. Autosomal recessive and X-linked recessive varieties are also known. First described by Hippocrates in 4 th century B.C., the various clinical types with variable penetrance have been described lately. The number of cases EDS reported in the literature is very meagre. With the available information only about six publications of classic EDS in siblings had been reported in Indian literature
Mycosis Fungoides: The great imitator
Introduction: Mycosis fungoides although a cutaneous T-Cell lymphoma can immitate many dermatological disorders. A 60 year old
man presented to our hospital with generalized annular plaques, few with verrucous surface. The annular lesions imitated Psoriasis,
Tinea, Syphilis and the diagnosis was in dilemma. Histopathology gave the light and path to diagnosis. Case report: A 60 year old
man presented with complains of erythematous scaly lesions since 20 year, Lesions were initially flat and erythematous which later
became ulcerated, crusted and painful. H/O exacerbation and remission was present. Conclusions: Mycosis Fungoides is a great
imitator both clinically and histopathologically. We are presenting a case report of patient with Mycosis Fungoides, Stage IIA
Livedo reticularis: A review of the literature
Livedo reticularis (LR) is a cutaneous physical sign characterized by transient or persistent, blotchy, reddish-blue to purple, net-like cyanotic pattern. LR is a benign disorder affecting mainly middle-aged females, whereas livedo racemosa (LRC) is pathologic, commonly associated with antiphospholipid antibody syndrome. This article aims to review the causes of LR and LRC along with the evaluation and management
Amoxicillin and clavulanate potassium related Leucocytoclastic vasculitis
Leukocytoclastic vasculitis (LCV) is a small-vessel vasculitis with a reported incidence rate of 30 cases per million persons per year. It usually presents as a palpable purpuric skin rash on legs, though any part of the body can be affected. LCV rash may have an associated burning sensation or pain and in some cases may involve internal organs. In some cases, LCV rash may present as nodules, recurrent ulcerations or asymptomatic lesions. The diagnosis of LCV is usually made on skin biopsy. Etiological triggers may not be identified in as many as half of the cases. Treatment is usually conservative and includes identification and removal or treatment of the etiological trigger except in cases with internal organ involvement where systemic steroids and immunosuppressant may be necessary. In this article we present a case of Amoxicillin and Clavulanate potassium associated LCV that improved with discontinuation of the offending agent and treatment with systemic corticosteroids