14 research outputs found
Cystic lymphangioma of the breast in an infant successfully managed with intralesional bleomycin: a case report with relevant review of the literature
Cystic hygromas, also known as lymphangiomas, are unusual congenital malformations of the lymphatic system and commonly involve the head and neck region or axilla. Involvement of other sites such as breasts is very rare. The preferred mode of treatment for lymphangioma of the breast in adults or children is surgery. We report a case of breast lymphangioma in a 3-month-old male child, which was managed successfully by intralesional bleomycin.Keywords: breast, bleomycin, intralesional sclerosing agent, macrocystic lymphangiom
Duplication cyst of pyloroduodenal canal: a rare cause of neonatal gastric outlet obstruction: a case report
This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens
Role of Fibrin Glue as a Sealant to Esophageal Anastomosis in Cases of Congenital Esophageal Atresia with Tracheoesophageal Fistula
Abstract Objective The aim of this study was to characterize a successful approach for the management of infants with long-gap esophageal atresia (EA) with tracheoesophageal fistula (TEF). The goal was to preserve the native esophagus and minimize the incidence of esophageal anastomotic leaks using fibrin glue as a sealant over the esophageal anastomosis. Method A total of 52 patients were evaluated in this study. Only patients in whom, gap between the two ends of the esophagus was ‡ 2 cm were selected durin
Juvenile polyposis syndrome
Aim: Report of a series of 12 cases of juvenile polyposis coli.
Methods: The study period was from 1995 to 2005. All the patients were
treated by total colectomy with rectal mucosectomy and endorectal
ileoanal pullthrough with or without ileal pouch formation. Covering
ileostomy was avoided in all the cases. Time taken for the surgery,
postoperative complications and continence were documented. Results:
The mean operating time was 4.2 h (range: 4-5 h). The mean duration of
hospital stay was 16.3 days (range: 15-18 days). The most common
postoperative complication was pouchitis and perianal excoriation.
Initially, all the patients were passing stools at an interval of 2 h,
and after 3 weeks, the frequency has reduced to 6-8 stools per day. In
the follow-up after 3 months, the frequency was 3-5 per day with
minimal soiling. Conclusions: Single-stage total colectomy with rectal
mucosectomy and endorectal ileoanal pull-through without covering
ileostomy and pouch formation is a safe and definitive treatment for
juvenile polyposis coli if the patient selection is appropriate
Histology of the Terminal End of the Distal Rectal Pouch and Fistula Region in Anorectal Malformations
OBJECTIVEUntil recently, surgeons have been posed with a dilemma—whether or not they should preserve the terminal end of the distal rectal pouch and the fistula region in anorectal malformations (ARMs). A detailed histological study of this region was conducted to establish a consensus for preserving or excising this region for reconstruction of ARMs.METHODSHistopathological examination using haematoxylin and eosin-stained sections of the terminal portion of the distal rectal pouch and proximal portion of the rectourogenital or rectoperineal connection was performed in 60 cases of high, intermediate and low ARMs.RESULTSDistorted internal sphincter was present in 93.3% of high, 90% of intermediate and 100% of low ARMs. The proximal fistula region was lined by transitional epithelium in 50% of cases, and anal glands were present in 83.3% and anal crypts in 68.3% of cases. The rectal pouch in the region of the internal sphincter and fistula was aganglionic in all cases.CONCLUSIONThis study shows that the terminal end of the distal rectal pouch and proximal fistula region possess distorted anal features with aganglionosis, and contradicts the recommendation that this region should be reconstructed in patients with malformations
Anterior Intratumoural Chemotherapy: A Newer Modality of Treatment in Advanced Solid Tumours in Children
OBJECTIVEAdvanced and inoperable solid tumours in children have high mortality despite aggressive multimodal treatment. Intravenous chemotherapy is abandoned at times because of systemic toxicity. This study investigated intratumoural chemotherapy and compared it with intravenous chemotherapy.METHODSForty children with advanced inoperable solid tumours (Wilms' tumour and neuroblastoma) were randomly allocated into two groups of 20. Group A was given intratumoural chemotherapy and group B was given intravenous chemotherapy. Both groups were compared for reduction in tumour size and volume, tumour resectability, histopathological changes and drug side effects.RESULTSIntratumoural chemotherapy was superior to intravenous chemotherapy in terms of reducing tumour size and volume (63% in group A vs. 22% in group B). The resectability was 70% in the intratumoural group compared with 40% in the intravenous group. The overall good histopathological response was 71% in group A as opposed to 0% in group B. Moreover, the incidence and severity of drug side effects and morbidity were less with intratumoural chemotherapy. Mortality was also low in group A (5%) compared to group B (20%).CONCLUSIONIntratumoural chemotherapy can be offered as an effective and safe alternative treatment modality for advanced and inoperable Wilms' tumour and neuroblastoma