2,067 research outputs found
How swelling debts give rise to a new type of politics in Vietnam
Vietnam has seen fast-rising debts, both domestic and external, in recent years. This paperreviews the literature on credit market in Vietnam, providing an up-to-date take on the domesticlending and borrowing landscape. The study highlights the strong demand for credit in both therural and urban areas, the ubiquity of informal lenders, the recent popularity of consumer financecompanies, as well as the government’s attempts to rein in its swelling public debt. Given thehigh level of borrowing, which is fueled by consumerism and geopolitics, it is inevitable that theamount of debt will soon be higher than the saving of the borrowers. Unlike the conventional wisdom that creditors have more bargaining power over the borrowers, we suggest that—albeitlacking a quantitative estimation—when the debts pile up so high that the borrowers could not repay, the power dynamics may reverse. In this new politics of debt, the lenders fear to lose the money's worth and continue to lend and feed the insolvent debtors. The result is a toxic lending/borrowing market and profound lessons, from which the developing world could learn
Dynamics and deposition of sediment-bearing multi-pulsed flows and geological implication
Previous studies on dilute, multi-pulsed, subaqueous saline flows have demonstrated that pulses will inevitably advect forwards to merge with the flow front. On the assumption that pulse merging occurs in natural-scale turbidity currents, it was suggested that multi-pulsed turbidites that display vertical cycles of coarsening and fining would transition laterally to single-pulsed, normally graded turbidites beyond the point of pulse merging. In this study, experiments of dilute, single- and multi-pulsed sediment-bearing flows (turbidity currents) are conducted to test the linkages between downstream flow evolution and associated deposit structure. Experimental data confirm that pulse merging occurs in laboratory-scale turbidity currents. However, only a weak correspondence was seen between longitudinal variations in the internal flow dynamics and the vertical structure of deposits; multi-pulsed deposits were documented, but transitioned to single-pulsed deposits before the pulse merging point. This early transition is attributed to rapid sedimentation-related depletion of the coarser-grained suspended fraction in the laboratory setting, whose absence may have prevented the distal development of multi-pulsed deposits; this factor complicates estimation of the transition point in natural-scale turbidite systems
Noncommutative gravity: fuzzy sphere and others
Gravity on noncommutative analogues of compact spaces can give a finite mode
truncation of ordinary commutative gravity. We obtain the actions for gravity
on the noncommutative two-sphere and on the noncommutative in
terms of finite dimensional -matrices. The commutative large
limit is also discussed.Comment: LaTeX, 13 pages, section on CP^2 added + minor change
Dynamics and Deposition of Sediment-Bearing Multi- Pulsed Flows and Geological Implication
Copyright © 2019, SEPM (Society for Sedimentary Geology) Previous studies on dilute, multi-pulsed, subaqueous saline flows have demonstrated that pulses will inevitably advect forwards to merge with the flow front. On the assumption that pulse merging occurs in natural-scale turbidity currents, it was suggested that multi-pulsed turbidites that display vertical cycles of coarsening and fining would transition laterally to single-pulsed, normally graded turbidites beyond the point of pulse merging. In this study, experiments of dilute, single- and multi-pulsed sediment-bearing flows (turbidity currents) are conducted to test the linkages between downstream flow evolution and associated deposit structure. Experimental data confirm that pulse merging occurs in laboratory-scale turbidity currents. However, only a weak correspondence was seen between longitudinal variations in the internal flow dynamics and the vertical structure of deposits; multi-pulsed deposits were documented, but transitioned to single-pulsed deposits before the pulse merging point. This early transition is attributed to rapid sedimentation-related depletion of the coarser-grained suspended fraction in the laboratory setting, whose absence may have prevented the distal development of multi-pulsed deposits; this factor complicates estimation of the transition point in natural-scale turbidite systems
Development and evaluation of a non-ribosomal random PCR and next-generation sequencing based assay for detection and sequencing of hand, foot and mouth disease pathogens
Reproductive performance in sows in relation to Japanese Encephalitis Virus seropositivity in an endemic area
Japanese Encephalitis Virus (JEV) is considered an important reproductive pathogen in pigs. Most studies of the reproductive impact of JEV have been conducted in areas where the disease occurs in seasonal epidemics. In this study, the associations between seropositivity for JEV, measured with an IgG ELISA, and the number of piglets born alive and stillborn were investigated in a tropical area endemic for JEV in Vietnam. Sixty percent of sows from four farms in the Mekong delta of Vietnam were seropositive to JEV and the Odds Ratio for a sow being infected was highest (6.4) in sows above 3.5 years (95% confidence interval 2.2–18.3). There was an association between increasing Optical Density (OD) values from the ELISA and the number of stillborn piglets in sows less than 1.5 years, but no effect of seropositivity could be shown when all sows were studied. OD values had an effect (p = 0.04) on the number of piglets born alive in the statistical analysis only when interacting with the effect of the breeds. An increase in mean OD value of the herd was correlated (p < 0.0001) with an increase in the number of piglets born alive. In this study, there was evidence of a negative association between seropositivity for JEV and the reproductive performance only in sows less than 1.5 years in endemic areas. This could be explained by a year-round infection with the virus, which would lead to immunity in many gilts before their first pregnancy. This, in turn, may imply that JEV infection in pigs is of minor importance for the reproductive performance in endemic areas
Properties of Graphene: A Theoretical Perspective
In this review, we provide an in-depth description of the physics of
monolayer and bilayer graphene from a theorist's perspective. We discuss the
physical properties of graphene in an external magnetic field, reflecting the
chiral nature of the quasiparticles near the Dirac point with a Landau level at
zero energy. We address the unique integer quantum Hall effects, the role of
electron correlations, and the recent observation of the fractional quantum
Hall effect in the monolayer graphene. The quantum Hall effect in bilayer
graphene is fundamentally different from that of a monolayer, reflecting the
unique band structure of this system. The theory of transport in the absence of
an external magnetic field is discussed in detail, along with the role of
disorder studied in various theoretical models. We highlight the differences
and similarities between monolayer and bilayer graphene, and focus on
thermodynamic properties such as the compressibility, the plasmon spectra, the
weak localization correction, quantum Hall effect, and optical properties.
Confinement of electrons in graphene is nontrivial due to Klein tunneling. We
review various theoretical and experimental studies of quantum confined
structures made from graphene. The band structure of graphene nanoribbons and
the role of the sublattice symmetry, edge geometry and the size of the
nanoribbon on the electronic and magnetic properties are very active areas of
research, and a detailed review of these topics is presented. Also, the effects
of substrate interactions, adsorbed atoms, lattice defects and doping on the
band structure of finite-sized graphene systems are discussed. We also include
a brief description of graphane -- gapped material obtained from graphene by
attaching hydrogen atoms to each carbon atom in the lattice.Comment: 189 pages. submitted in Advances in Physic
Host Transcription Profile in Nasal Epithelium and Whole Blood of Hospitalized Children Under 2 Years of Age With Respiratory Syncytial Virus Infection.
BACKGROUND: Most insights into the cascade of immune events after acute respiratory syncytial virus (RSV) infection have been obtained from animal experiments or in vitro models. METHODS: In this study, we investigated host gene expression profiles in nasopharyngeal (NP) swabs and whole blood samples during natural RSV and rhinovirus (hRV) infection (acute versus early recovery phase) in 83 hospitalized patients <2 years old with lower respiratory tract infections. RESULTS: Respiratory syncytial virus infection induced strong and persistent innate immune responses including interferon signaling and pathways related to chemokine/cytokine signaling in both compartments. Interferon-α/β, NOTCH1 signaling pathways and potential biomarkers HIST1H4E, IL7R, ISG15 in NP samples, or BCL6, HIST2H2AC, CCNA1 in blood are leading pathways and hub genes that were associated with both RSV load and severity. The observed RSV-induced gene expression patterns did not differ significantly in NP swab and blood specimens. In contrast, hRV infection did not as strongly induce expression of innate immunity pathways, and significant differences were observed between NP swab and blood specimens. CONCLUSIONS: We conclude that RSV induced strong and persistent innate immune responses and that RSV severity may be related to development of T follicular helper cells and antiviral inflammatory sequelae derived from high activation of BCL6
Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context
Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts
Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas
This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing
molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin
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