1,089 research outputs found

    Behind the Scenes: A Look at Socio-cultural Messages in Situation Comedies and their Effects on Gendered Messages

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    Specific values, characteristics and behaviors are expected for men and women in American society. Previous research has shown that gender stereotypes on television programs are believed to influence society\u27s “perception of appropriate sex roles” and reinforce negative notions about the role of women in society (Fullteron et al. 2000). According to Lee & Shaw (2010), matters have not changed much. Television uses speech that creates images of and attitudes towards women that prevent equality. This study undertakes a content analysis of two prime-time television shows, 2 Broke Girls and Happy Endings. The objective of this research is to analyze the extent to which societal beliefs concerning stereotyped gender roles are reinforced on television. The analysis of 2 Broke Girls and Happy Endings illustrates the perpetuation of sexist attitudes and behaviors on prime-time television. This demonstrates social and gender divides in society

    Men’s experiences of help-seeking for female-perpetrated intimate partner violence: A qualitative exploration

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    The subject of female-perpetrated intimate partner violence (IPV) against men has been one of controversy, with well-rehearsed arguments surrounding both the nature and existence of female-perpetrated abuse against men. The aims of this study were to explore men's help-seeking experiences and/or their perceptions of utilising support services/support networks following IPV victimisation. Consequently, this study explored the help-seeking experiences of 26, largely British, men who self-identified as having experienced female-perpetrated IPV. As the focus was on subjective experiences, a qualitative design was employed. Participation was invited from men who had sought help for their IPV victimisation from a range of sources and those who had not sought help at all. Semi-structured interviews explored the men's experiences of seeking help, and barriers to seeking help, following IPV. The data were analysed using reflexive thematic analysis. Some of the participants who took part in this study had received formal support for their experiences of IPV (i.e. counselling, calling IPV helplines and support services, contact with social workers or the police) and informal support (e.g. speaking to work colleagues, family and friends). Five participants had never spoken to anybody about their experiences prior to taking part in the interview. A range of barriers prevented the men from seeking help. First and foremost, the importance of maintaining a sense of masculinity consistently underpinned the participants’ narratives. The men's fear of being judged negatively by others was often not unfounded. Negative help-seeking experiences included being treated with suspicion and contempt. Positive help-seeking experiences facilitated the men in recognising their relationship as abusive, which for some of the men was influential in their decision to leave or seek help. The lack of recognition and understanding of male IPV within society was of concern to most of the men. Some expressed a desire to use their own experiences in order to help other men in abusive relationships. These results have important implications for the development of appropriate support for male victims, including the need for practitioners to be non-judgemental whilst assisting men in recognising their relationship as abusive

    FLT3 Inhibition in acute myeloid leukaemia - current knowledge and future prospects

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    Activating mutations of FMS-like tyrosine kinase 3 (FLT3) are present in 30% of acute myeloid leukaemia (AML) patients at diagnosis and confer an adverse clinical prognosis. Mutated FLT3 has emerged as a viable therapeutic target and a number of FLT3-directed tyrosine kinase inhibitors have progressed through clinical development over the last 10-15 years. The last two years have seen United States Food and Drug Administration (US FDA) approvals of the multi-kinase inhibitor midostaurin for newly-diagnosed FLT3-mutated patients, when used in combination with intensive chemotherapy, and of the more FLT3-selective agent gilteritinib, used as monotherapy, for patients with relapsed or treatment-refractory FLT3-mutated AML. The ‘second generation’ agents, quizartinib and crenolanib, are also at advanced stages of clinical development. Significant challenges remain in negotiating a variety of potential acquired drug resistance mechanisms and in optimizing sequencing of FLT3 inhibitory drugs with existing and novel treatment approaches in different clinical settings, including frontline therapy, relapsed/refractory disease, and maintenance treatment. In this review, the biology of FLT3, the clinical challenge posed by FLT3-mutated AML, the developmental history of the key FLT3-inhibitory compounds, mechanisms of disease resistance, and the future outlook for this group of agents, including current and planned clinical trials, is discussed

    The Impact of Masculine Ideologies on Heterosexual Men’s Experiences of Intimate Partner Violence: A Qualitative Exploration

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    The subject of female-perpetuated intimate partner violence (IPV) against men remains poorly understood and in need of further research. Exploration of societal expectations surrounding masculinity and male victimization may enhance understanding of how men experience IPV victimization. Consequently, this experiential research study explored the impact of masculine ideologies on the way in which 26 men made sense of their experiences of femaleperpetrated intimate partner violence (IPV). Semi-structured interviews explored the men’s sense of themselves, their relationship, and their use of support networks. The data were analyzed using reflexive thematic analysis. The importance of maintaining an appropriate sense of masculinity underpinned the men’s narratives. Participants described feeling shame and embarrassment for not having met dominant cultural expectations surrounding the roles of men in heterosexual relationships. Many of the participants struggled to accept the role of “victim,” which was perceived as demasculinizing. These findings offer implications for understanding men’s experiences of IPV and developing enhanced sources of support

    The impact of masculine ideologies on heterosexual men’s experiences of intimate partner violence: A qualitative exploration

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    The subject of female-perpetuated intimate partner violence (IPV) against men remains poorly understood and in need of further research. Exploration of societal expectations surrounding masculinity and male victimization may enhance understanding of how men experience IPV victimization. Consequently, this experiential research study explored the impact of masculine ideologies on the way in which 26 men made sense of their experiences of female-perpetrated intimate partner violence (IPV). Semi-structured interviews explored the men’s sense of themselves, their relationship, and their use of support networks. The data were analyzed using reflexive thematic analysis. The importance of maintaining an appropriate sense of masculinity underpinned the men’s narratives. Participants described feeling shame and embarrassment for not having met dominant cultural expectations surrounding the roles of men in heterosexual relationships. Many of the participants struggled to accept the role of “victim,” which was perceived as de-masculinizing. These findings offer implications for understanding men’s experiences of IPV and developing enhanced sources of support

    Evaluation of environmental sampling methods for detection of Staphylococcus aureus on fomites

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    We evaluated a variety of methods to recover S. aureus from inanimate surfaces. Two contact agar plates and three swab sampling methods were tested on porous and non-porous surfaces and bar soap. The cost and ease of use of each method was also evaluated. S. aureus was recovered using all methods on both porous and non-porous surfaces. S. aureus could not be detected on three of four brands of soap

    The Canadian Neuromuscular Disease Registry: Connecting Patients to National and International Research Opportunities

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    Introduction Patient registries serve an important role in rare disease research, particularly for the recruitment and planning of clinical trials. The Canadian Neuromuscular Disease Registry was established with the primary objective of improving the future for neuromuscular (NM) patients through the enablement and support of research into potential treatments. Methods In this report, we discuss design and utilization of the Canadian Neuromuscular Disease Registry with special reference to the paediatric cohort currently enrolled in the registry. Results As of July 25, 2017, there are 658 paediatric participants enrolled in the registry, 249 are dystrophinopathies (229 are Duchenne muscular dystrophy), 57 are myotonic dystrophy participants, 98 spinal muscular atrophy participants and 65 are limb girdle muscular dystrophy. A total of 175 patients have another NM diagnosis. The registry has facilitated 20 clinical trial inquiries, 5 mail-out survey studies and 5 other studies in the paediatric population. Discussion The strengths of the registry are discussed. The registry has proven to be an invaluable tool to NM disease research and has increased Canada’s visibility as a competitive location for the conduct of clinical trials for NM therapies

    Promoting the health of children and young people who migrate: reflections from four regional reviews

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    Calls to enhance the health of migrant population sub-groups are strengthening, with increasing evidence documenting the relationship between migration and health outcomes. Despite the importance of migration to global health promotion, little research has focused on the health experiences of young migrants. As part of a Worldwide University Network project, we completed four systematic reviews examining the existing evidence base on the health experiences of children and young people who migrate. In this commentary, we share commonalities with the international evidence but also reflect on some of the challenges, omissions and limitations. These insights expose significant gaps and methodological shortcomings in the evidence – providing space for new research that seeks to identify the influences on migrant children’s health

    Identifying inaccuracies on emergency medicine residency applications

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    BACKGROUND: Previous trials have showed a 10–30% rate of inaccuracies on applications to individual residency programs. No studies have attempted to corroborate this on a national level. Attempts by residency programs to diminish the frequency of inaccuracies on applications have not been reported. We seek to clarify the national incidence of inaccuracies on applications to emergency medicine residency programs. METHODS: This is a multi-center, single-blinded, randomized, cohort study of all applicants from LCME accredited schools to involved EM residency programs. Applications were randomly selected to investigate claims of AOA election, advanced degrees and publications. Errors were reported to applicants' deans and the NRMP. RESULTS: Nine residencies reviewed 493 applications (28.6% of all applicants who applied to any EM program). 56 applications (11.4%, 95%CI 8.6–14.2%) contained at least one error. Excluding "benign" errors, 9.8% (95% CI 7.2–12.4%), contained at least one error. 41% (95% CI 35.0–47.0%) of all publications contained an error. All AOA membership claims were verified, but 13.7% (95%CI 4.4–23.1%) of claimed advanced degrees were inaccurate. Inter-rater reliability of evaluations was good. Investigators were reluctant to notify applicants' dean's offices and the NRMP. CONCLUSION: This is the largest study to date of accuracy on application for residency and the first such multi-centered trial. High rates of incorrect data were found on applications. This data will serve as a baseline for future years of the project, with emphasis on reporting inaccuracies and warning applicants of the project's goals
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