Epidemiological Peculiarities and Clinical Features of Ebola Virus Disease in the Republic of Guinea

The current outbreak of the Ebola fever in West Africa is unprecedented in terms of its scale. As of today, 27550 suspected cases and 11235 deaths have been reported. The outbreak differs from previous epidemics in terms of epidemiological and clinical progression of the disease. The article covers several epidemiological issues related to Ebola virus disease by the example of the Guinean outbreak, which has been plaguing the country since 2014. Given is the preliminary clinical analysis of the medical observations, performed in the Research and Diagnostic Centre of Epidemiology and Microbiology built by RUSAL. Regarded are epidemiological and clinical features of the Ebola virus disease (EVD) in 83 patients, who were admitted to RUSAL Treatment Center since March 6th till June 30th, 2015. In 28 of the patients, EVD diagnosis was laboratory confirmed. The principle assessment criteria are: morbidity rate, lethality index, gender, age, occupation, time since the onset of the disease until hospitalization, an average duration of the stay at the hospital, complaints, symptoms, complications, and the therapy provided

Composite vortex-ring solitons in Bessel photonic lattices

We reveal the existence of dynamically stable composite topological solitons in Bessel photonic lattices imprinted in focusing Kerr-type nonlinear media. The new stable composite solitons are made of a vortex-ring with unit topological charge incoherently coupled to a fundamental soliton. The stabilization of the otherwise highly azimuthally unstable vortex-rings is provided under suitable conditions, which we study in detail, by cross-phase-modulation coupling with the fundamental soliton companion.Comment: 13 pages, 3 figures, to appear in Journal of the Optical Society of America

Humans Infected with Relapsing Fever Spirochete Borrelia miyamotoi, Russia

Disease may occur throughout the world because of the widespread prevalence of this pathogen in ixodid ticks

Implementation of Imitation Hypoxic Workout when Training Highly Qualified Downhill Skiers Based on Physical Exercise Individualization

В работе приводятся итоги экспериментального исследования, направленного на выяснение вопроса о возможности применения в подготовке лыжников-гонщиков высокой квалификации искусственной гипоксической тренировки (ИГТ), которая в сочетании с общепринятыми средствами спортивной тренировки обеспечивает высокий уровень достижений в отдельных видах спорта. В публикации представлены показатели физической нагрузки в микро- и мезоциклах подготовительного периода, а также направленность и содержание разработанной авторами методики развития специальной физической подготовленности высококвалифицированных лыжников-гонщиков при использовании различных средств и методов искусственной гипоксической тренировки. Доказана эффективность экспериментальной методики в повышении уровня физической подготовленности, функционального резерва организма спортсменов и результативности их соревновательной . This article presents the results of research on the expediency of imitation hypoxic workout when training highly qualified downhill skiers. This method, along with some other sports training methods, provides for impressive results in certain kinds of sport. This paper shows the indicators of physical exercise in micro and mesocycle of pre-season, as well as the material on the expediency of imitation hypoxic workout when training highly qualified downhill skiers. The effectiveness of experimental methods in increasing physical fitness as well as “the functional reservoir” of sportsmen’s bodies and their competitiveness has been proved

Expanding the Family of Octahedral Chiral-at-Metal Cobalt(III) Catalysts by Introducing Tertiary Amine Moiety into the Ligand

Chiral metal-templated complexes are attractive catalysts for organic synthetic transformations. Herein, we introduce a novel chiral cobalt(III)-templated complex based on chiral trans-3,4-diamino-1-benzylpyrrolidine and 3,5-di-tert-butyl-salicylaldehyde which features both hydrogen bond donor and Brønsted base functionalities. The obtained complexes were fully characterized by 1H, 13C NMR, IR-, UV-vis, CD-spectroscopy and by a single X-ray diffraction analysis. It was shown that chlorine anion is connected with amino groups of the complex via a hydrogen bonding. DFT calculations of charges and molecular electrostatic potential of the cobalt(III) complex showed that the basicity of the complex is certainly diminished as compared with the routine tertiary amines but the acidity of the conjugated acid of the complex should be increased. Thus, the catalytic potential of the complex may be much greater as a chiral acid than a chiral base. We believe that this work opens a new way in chiral bifunctional catalyst design

CCDC 927098: Experimental Crystal Structure Determination

Related Article: Yuri N. Belokon, Victor I. Maleev, Michael North, Vladimir A. Larionov, Tat’yana F. Savel’yeva, Aike Nijland, and Yuliya V. Nelyubina|2013|ACS Catalysis|3|1951|doi:10.1021/cs400409d,An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

CCDC 927099: Experimental Crystal Structure Determination

Related Article: Yuri N. Belokon, Victor I. Maleev, Michael North, Vladimir A. Larionov, Tat’yana F. Savel’yeva, Aike Nijland, and Yuliya V. Nelyubina|2013|ACS Catalysis|3|1951|doi:10.1021/cs400409d,An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Self-Assembled Ionic Composites of Negatively Charged Zn(salen) Complexes and Triphenylmethane Derived Polycations as Recyclable Catalysts for the Addition of Carbon Dioxide to Epoxides

The design and synthesis of a novel type of self-assembled ionic composite composed of negatively charged Zn(salen) complexes and triphenylmethane derived polycations is reported. These composites were applied as easily recyclable catalysts for carbon dioxide addition to epoxides. The composites functioned as bifunctional catalysts which could be easily separated and recycled by precipitation from the reaction mixture upon addition of tetrachloromethane. The same batch of the catalyst could be employed for, at least, five runs with its catalytic properties improving as it was reused. A fully heterogeneous system was also prepared by cross-linking leuco dye with para-dibromoxylene and adding to it calculated amounts of Zn(salen) complex. The heterogeneous system was catalytically competent in the reaction between styrene oxide and carbon dioxide and its activity also increased on its reuse