Biography of Augustus Barie

Augustus Barie was born in Augusta, Georgia on July 15, 1815. While he was still a boy, his family moved to Savannah, Georgia; here, his father became the French Consul.https://digitalcommons.georgiasouthern.edu/sav-bios-lane/1012/thumbnail.jp

Measuring Organizational Climate for Diversity

The Climate for Diversity Index measures three dimensions associated with the ability of organizations or units to create an environment that allows members of all sociocultural backgrounds to participate and fully develop. The climate for diversity impacts individual outcomes such as general job satisfaction, affective commitment, identification with a psychological group/department, organizational citizenship behavior, and the intent to turnover. Several structural models depicting the relationship between the climate for diversity and the individual outcome variables were examined. Significant differences in perceptions of the climate for diversity are predicted by ethnicity, disability, and position. Data were provided by 319 members of a wide variety of organizations including hospitals, banks, and athletic clubs. Tests of reliability and validity indicate that the Climate for Diversity Index is a dependable instrument for the assessment of the climate for diversity. The scale reflects intentionally designed openness to diversity differences in the environment. The scale is internally consistent and distinct from social desirability and the desirability of diversity. Participants were probed at the group level. However, evidence supporting aggregation is contradictory; the analysis of variance and the test of interrater reliability suggest that aggregation is appropriate, but the conservative within- and between-analysis rejects the group level. The a priori and alternate structural models were examined with both disaggregated and aggregated data. The model of best fit was the a priori model using disaggregated data. Thus, the construct may be best considered at the individual level of analysis. Implications of an independent climate for diversity construct are fully discussed

Improving Health Outcomes in Persons with Sickle Cell Disease

Purpose: The purpose of this compendium is to identify strategies that influence health outcomes of persons with sickle cell disease (SCD) by investigating available pain instruments, current use of genetic testing to personalize therapies, and the associations of psychosocial characteristics with quality of life. Problem: Suboptimal care for patients with SCD is associated with non-comprehensive pain assessment instruments, limited use of available genetic tests to prescribe the potentially most effective pharmaceuticals in a personalized plan of care, and the absence of national evidence-based guidelines for the psychosocial care of this population. Approach: The research designs used were an integrative review with a biopsychosocial-religiosity/spirituality (BPS-R/S) framework, a literature review using Diffusion of Innovation as a framework, and a quantitative study guided by the Theory of Self-Care Management for Sickle Cell Disease using secondary analysis. Findings: The integrative review suggested that pain control outcomes might be improved by incorporating biopsychosocial-religiosity/spirituality measures to the pain instruments. The literature review indicated that the use of available genetic tests to determine the efficacy of pharmaceutical treatment options might lead to personalized care in the person with SCD. The secondary analysis found that the association between psychological factors and quality of life in the SCD sample was significant and suggested that randomized controlled trials be conducted to confirm findings prospectively. The overall findings identified that persons with SCD have complex needs inherent in a disease process that affects all body systems. Pain is the hallmark characteristic of the disease and is a dynamic biopsychosocial phenomenon. Conclusion: BPS-R/S and genetic domains contribute to humanistic care and may benefit persons with SCD. Persons with SCD may experience improved health outcomes when the biopsychosocial- religiosity/spirituality dimensions are supported by services in the healthcare environment. The implementation of these findings through researcher, provider, patient, and family education may improve health outcomes and quality of life

Promoting Social-emotional Wellbeing in Early Intervention Services: A Fifty-state View

In 2007 approximately 322,000 young children received services through the Individuals with Disabilities Act (IDEA) Part C, the Early Intervention Program for Infant and Toddlers with Disabilities. Yet research shows that only a fraction of children eligible for the program received services. Against the backdrop of this gap between need for services and service use, special concerns for young children with or at risk for social-emotional developmental delays stand in relief. Even fewer of these children received services to address their social-emotional developmental needs through Part C. In part, this state of affairs reflects the significant flexibility states have in the eligibility criteria used to identify children who will receive services under Part C. However, this flexibility results in significant differences in the number of children identified in specific states. Eligibility criteria are categorized into three groups: restricted, which includes in the determination neither clinical input nor children at-risk for developmental delay; narrow, which does include a clinical option but not at risk children; and liberal, which can include both the clinical option and at-risk children

Whole-blood sorting, enrichment and in situ immunolabeling of cellular subsets using acoustic microstreaming

Analyzing undiluted whole human blood is a challenge due to its complex composition of hematopoietic cellular populations, nucleic acids, metabolites, and proteins. We present a novel multi-functional microfluidic acoustic streaming platform that enables sorting, enrichment and in situ identification of cellular subsets from whole blood. This single device platform, based on lateral cavity acoustic transducers (LCAT), enables (1) the sorting of undiluted donor whole blood into its cellular subsets (platelets, RBCs, and WBCs), (2) the enrichment and retrieval of breast cancer cells (MCF-7) spiked in donor whole blood at rare cell relevant concentrations (10 mL− 1), and (3) on-chip immunofluorescent labeling for the detection of specific target cellular populations by their known marker expression patterns. Our approach thus demonstrates a compact system that integrates upstream sample processing with downstream separation/enrichment, to carry out multi-parametric cell analysis for blood-based diagnosis and liquid biopsy blood sampling

Social-emotional Development in Early Childhood: What Every Policymaker Should Know

The early years of life present a unique opportunity to lay the foundation for healthy development. It is a time of great growth and of vulnerability. Research on early childhood has underscored the impact of the first five years of a child's life on his/her social-emotional development. Negative early experiences can impair children's mental health and effect their cognitive, behavioral, social-emotional development

Chemical composition of A and F dwarfs members of the Hyades open cluster

Aims: Abundances of 15 chemical elements have been derived for 28 F and 16 A stars members of the Hyades open cluster in order to set constraints on self-consistent evolutionary models that include radiative and turbulent diffusion. Methods: A spectral synthesis, iterative procedure was applied to derive the abundances from selected high-quality lines in high-resolution, high-signal-to-noise spectra obtained with SOPHIE and AURELIE at the Observatoire de Haute Provence. Results: The abundance patterns found for A and F stars in the Hyades resemble those observed in Coma Berenices and Pleiades clusters. In graphs representing the abundances versus the effective temperature, A stars often display much more scattered abundances around their mean values than the coolest F stars do. Large star-to-star variations are detected in the Hyades A dwarfs in their abundances of C, Na, Sc, Fe, Ni, Sr, Y, and Zr, which we interpret as evidence of transport processes competing with radiative diffusion. In A and Am stars, the abundances of Cr, Ni, Sr, Y, and Zr are found to be correlated with that of Fe as in the Pleiades and in Coma Berenices. The ratios C/Fe and O/Fe are found to be anticorrelated with Fe/H as in Coma Berenices. All Am stars in the Hyades are deficient in C and O and overabundant in elements heavier than Fe but not all are deficient in Ca and/or Sc. The F stars have solar abundances for almost all elements except for Si. The overall shape of the abundance pattern of the slow rotator HD 30210 cannot be entirely reproduced by models including radiative diffusion and different amounts of turbulent diffusion. Conclusions: While part of the discrepancies between derived and predicted abundances could come from non-LTE effects, including competing processes such as rotational mixing and/or mass loss seems necessary in order to improve the agreement between the observed and predicted abundance patterns