626 research outputs found
Initiation factors in protein synthesis by free and membrane-bound polyribosomes of liver and hepatoma
High-spin states with seniority v=4,4,6 in 119-126Sn
The 119-126Sn nuclei have been produced as fission fragments in two reactions
induced by heavy ions: 12C+238U at 90 MeV bombarding energy, 18O+208Pb at 85
MeV. Their level schemes have been built from gamma rays detected using the
Euroball array. High-spin states located above the long-lived isomeric states
of the even- and odd-A 120-126Sn nuclei have been identified. Moreover isomeric
states lying around 4.5 MeV have been established in 120,122,124,126Sn from the
delayed coincidences between the fission fragment detector SAPhIR and the
Euroball array. The states located above 3-MeV excitation energy are ascribed
to several broken pairs of neutrons occupying the nu h11/2 orbit. The maximum
value of angular momentum available in such a high-j shell, i.e. for
mid-occupation and the breaking of the three neutron pairs, has been
identified. This process is observed for the first time in spherical nuclei.Comment: 20 pages, 22 figures, 12 tables, accepted for publication in Physical
Review
Efficacy of the EGFr inhibitor Iressa on development of chemically-induced urinary bladder cancers: Dose dependency and modulation of biomarkers
The High Burden of Malaria in Primary School Children in Southern Malawi.
Malaria among school children has received increased attention recently, yet there remain few detailed data on the health and educational burden of malaria, especially in southern Africa. This paper reports a survey among school children in 50 schools in Zomba District, Malawi. Children were assessed for Plasmodium infection, anemia, and nutritional status and took a battery of age-appropriate tests of attention, literacy, and numeracy. Overall, 60.0% of children were infected with Plasmodium falciparum, 32.4% were anemic and 32.4% reported sleeping under a mosquito net the previous night. Patterns of P. falciparum infection and anemia varied markedly by school. In multivariable analysis, higher odds of P. falciparum infection were associated with younger age and being stunted, whereas lower odds were associated with reported net use, higher parental education, and socioeconomic status. The odds of anemia were significantly associated with P. falciparum infection, with a dose-response relationship between density of infection and odds of anemia. No clear relationship was observed between health status and cognitive and educational outcomes. The high burden of malaria highlights the need to tackle malaria among school children
Design, implementation and evaluation of a training programme for school teachers in the use of malaria rapid diagnostic tests as part of a basic first aid kit in southern Malawi.
BACKGROUND: With increasing levels of enrolment, primary schools present a pragmatic opportunity to improve the access of school children to timely diagnosis and treatment of malaria, increasingly recognised as a major health problem within this age group. The expanded use of malaria rapid diagnostic tests (RDTs) and artemisinin combination therapy (ACT) by community health workers (CHWs) has raised the prospect of whether teachers can provide similar services for school children. We describe and evaluate the training of primary school teachers to use a first aid kit containing malaria RDTs and ACT for the diagnosis and treament of uncomplicated malaria in school children in southern Malawi. METHODS: We outline the development of the intervention as: (1) conception and design, (2) pilot training, (3) final training, and (4) 7-month follow up. The training materials were piloted at a four-day workshop in July 2013 following their design at national stakeholders meetings. The evaluation of the pilot training and materials were assessed in relation to increased knowledge and skill sets using checklist evaluations and questionnaires, the results of which informed the design of a final seven-day training programme held in December 2013. A follow up of trained teachers was carried out in July 2014 following 7 months of routine implementation. A total of 15 teachers were evaluated at four stages: pilot training, two weeks following pilot, final training and seven months following final training. RESULTS: A total of 15 and 92 teachers were trained at the pilot and final training respectively. An average of 93 % of the total steps required to use RDTs were completed correctly at the final training, declining to 87 % after 7 months. All teachers were observed correctly undertaking safe blood collection and handling, accurate RDT interpretation, and correct dispensing of ACT. The most commonly observed errors were a failure to wait 20 minutes before reading the test result, and adding an incorrect volume of buffer to the test cassette. CONCLUSION: Following training, teachers are able to competently use RDTs and ACTs test and treat children at school for uncomplicated malaria safely and accurately. Teachers demonstrate a comparable level of RDT use relative to non-health professional users of RDTs, and sustain this competency over a period of seven months during routine implementation
Quadrupole moment of the 6− isomeric state in 66Cu: Interplay between different nuclear deformation driving forces
AbstractWe have measured the spectroscopic quadrupole moment of the 6− isomeric state in 66Cu to be |Qs|=18.6(12) efm2. This state results from a weak coupling of the πp3/2 and the νg9/2 orbitals, which lead to sizable deformation at oblate and prolate shapes, correspondingly, in the 68Ni region. The interplay between these two different deformation-driving orbitals is observed at N=37 for the 6− state resulting in a most probable oblate shape
Charge-radius change and nuclear moments in the heavy tin isotopes from laser spectroscopy: Charge radius of Sn
NESTER ACCLaser spectroscopy measurements have been carried out on the neutron-rich tin isotopes with the COMPLIS experimental setup. Using the optical transition, hyperfine spectra of Sn and were recorded for the first time. The nuclear moments and the mean square charge radius variation (\delta, the absolute charge radii of these isotopes were deduced in particular that of the doubly magic Sn nucleus. The comparison of the results with several mean-field-type calculations have shown that dynamical effects play an important role in the tin isotopes
Running from Paris to Beijing: biomechanical and physiological consequences
Abstract The purpose of this study was to examine the physiological and biomechanical changes occurring in a subject after running 8,500 km in 161 days (i.e. 52.8 km daily). Three weeks before, 3 weeks after (POST) and 5 months after (POST?5) running from Paris to Beijing, energy cost of running (Cr), knee flexor and extensor isokinetic strength and biomechanical parameters (using a treadmill dynamometer) at different velocities were assessed in an experienced ultra-runner. At POST, there was a tendency toward a 'smoother' running pattern, as shown by (a) a higher stride frequency and duty factor, and a reduced aerial time without a change in contact time, (b) a lower maximal vertical force and loading rate at impact and (c) a decrease in both potential and kinetic energy changes at each step. This was associated with a detrimental effect on Cr (?6.2%) and a loss of strength at all angular velocities for both knee flexors and extensors. At POST?5, the subject returned to his original running patterns at low but not at high speeds and maximal strength remained reduced at low angular velocities (i.e. at high levels of force). It is suggested that the running pattern changes observed in the present study were a strategy adopted by the subject to reduce the deleterious effects of long distance running. However, the running pattern changes could partly be linked to the decrease in maximal strength
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