Anse Trabaud commune de Sainte-Anne, Martinique:reconstruction d’un village amérindien. Son insertion dans le réseau d’échanges Antillais entre 600 et 1200 après J.-C. Rapport final, prospection thématique, sondages et fouille 2012 et 2015.

Archaeology of indigenous Americ

Mangrove archives: unravelling human-environment interactions from deeply buried deposits at the site Anse Trabaud, Martinique, Lesser Antilles (1290–780 cal BP)

The site of Anse Trabaud on Martinique in the Windward Islands of the Lesser Antilles has yielded valuable information about human occupation from deep beneath its surface. The site is located in the southeastern part of the island, an area vulnerable to extreme wave events. The archaeological deposits are dated to 1290–780 cal BP (2σ). The earliest horizon is buried under thick layers of mangrove sediments. The deeply buried deposits have allowed excellent preservation of inorganic and organic remains providing an unexpected opportunity to reconstruct the paleoenvironmental conditions of past human settlement, and to study human-environment interactions and social adaptation to climate challenges in this part of the Caribbean archipelago. The cultural remains provide invaluable information into the exploitation of the surroundings of the site as well as into the subsistence patterns, material culture repertoires, procurement strategies and use and exchange of raw materials and tools. Additionally, the excellent preservation of organic materials offers new insights into food plants grown and harvested on-site, and then processed and consumed. The environmental challenges incited the Anse Trabaud community to adapt their settlement organisation and procurement strategies over time and underscore the importance of their participation in a regional and social network of mobility and exchange.Seventh Framework Programme (FP7)319209Bioarchaeolog

Impact of the lockdown on acute stroke treatments during the first surge of the COVID-19 outbreak in the Netherlands

INTRODUCTION: We investigated the impact of the Corona Virus Disease 2019 (COVID-19) pandemic and the resulting lockdown on reperfusion treatments and door-to-treatment times during the first surge in Dutch comprehensive stroke centers. Furthermore, we studied the association between COVID-19-status and treatment times. METHODS: We included all patients receiving reperfusion treatment in 17 Dutch stroke centers from May 11th, 2017, until May 11th, 2020. We collected baseline characteristics, National Institutes of Health Stroke Scale (NIHSS) at admission, onset-to-door time (ODT), door-to-needle time (DNT), door-to-groin time (DGT) and COVID-19-status at admission. Parameters during the lockdown (March 15th, 2020 until May 11th, 2020) were compared with those in the same period in 2019, and between groups stratified by COVID-19-status. We used nationwide data and extrapolated our findings to the increasing trend of EVT numbers since May 2017. RESULTS: A decline of 14% was seen in reperfusion treatments during lockdown, with a decline in both IVT and EVT delivery. DGT increased by 12 min (50 to 62 min, p-value of < 0.001). Furthermore, median NIHSS-scores were higher in COVID-19 - suspected or positive patients (7 to 11, p-value of 0.004), door-to-treatment times did not differ significantly when stratified for COVID-19-status. CONCLUSIONS: During the first surge of the COVID-19 pandemic, a decline in acute reperfusion treatments and a delay in DGT was seen, which indicates a target for attention. It also appeared that COVID-19-positive or -suspected patients had more severe neurologic symptoms, whereas their EVT-workflow was not affected. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12883-021-02539-4

The discovery of a precolonial Golden Rock structure on the eve of destruction, St. Eustatius (Netherlands Antilles)

Archaeology of indigenous Americ

Severely disturbed sleep in patients with acute ischemic stroke on stroke units: A pilot study

Introduction: Previous studies revealed a high prevalence of sleep-wake disturbances in subacute and chronic stroke. We analyzed sleep quantity and quality in patients with hyperacute ischemic stroke on stroke units. Methods: We categorized sleep stages as N1, N2, N3, and REM according to the 2017 criteria of the American Academy of Sleep Medicine in 23 continuous, overnight EEG registrations from 18 patients, starting within 48 h since the onset of cortical ischemic stroke. Associations between presence and duration of sleep stages, and secondary deterioration or functional outcome were analyzed. Results: Physiological sleep cycles were seen in none of the patients. Otherwise, sleep stages alternated chaotically, both during day-and during nighttime, with a sleep efficiency of 30% and 10.5 ± 4.4 (mean ± SD) awakenings per hour of sleep. We cannot differentiate between stroke related and external factors. Only few interruptions could be related to planned nightly wake up calls, but turbulence on stroke units may have played a role. Six patients (seven nights) did not reach deep sleep (N3), 10 patients (13 nights) did not reach REM sleep. If reached, the mean durations of deep and REM sleep were short, with 37 (standard deviation (SD) 25) and 18 (SD15) minutes, respectively. Patients with secondary deterioration more often lacked deep sleep (N3) than patients without secondary deterioration [4 (57%) vs. 2 (25%)], but without statistical significance (p = 0.12). Conclusion: We show that sleep is severely disturbed in patients with acute ischemic stroke admitted to stroke units. Larger studies are needed to clarify associations between deprivation of deep sleep and secondary deterioration

Predicting coastal erosion in St. Kitts: Collaborating for nature and culture

Archaeology of the America

Contralesional Brain Activity in Acute Ischemic Stroke

Background: The noninjured, contralateral hemisphere is increasingly acknowledged in the process of recovery from acute ischemic stroke. We estimated the value of conventional electroencephalography (EEG) recordings for identifying contralateral hemisphere involvement in relation to functional recovery. Methods: We analyzed 2-min epochs from 21 electrode EEG registrations of 18 patients with acute hemispheric ischemic stroke and compared with 18 age-matched controls. Outcome was dichotomized as good (modified Rankin Scale [mRS] 0-2) or poor (mRS 3-5 or death) at 3 months. Effects of the infarct on the ipsi-and contralateral hemispheres were analyzed by the delta/alpha ratio (DAR) and 2 measures of functional connectivity (magnitude squared coherence [MSC] and weighted phase lag index [WPLI]). Results: DAR was higher in patients than in controls, both in the ipsilateral and in the contralateral hemisphere (median 4.5 ± 6.7 ipsilateral and 2.4 ± 2.0 contralateral vs. 0.5 ± 0.5 in the control group, p < 0.001), indicating robust EEG changes in both lesioned and non-lesioned hemisphere. MSC and WPLI in the alpha and beta frequency bands were lower in patients than in controls in both hemispheres, indicating clear disturbances of functional connectivity (p < 0.05). In the poor outcome group, contralateral MSC and WPLI were lower than in the good outcome group, although these differences did not reach statistical significance. Conclusions: Short conventional EEG measurements show robust changes of brain activity and functional connectivity in both ipsilateral and contralateral hemispheres of patients with acute ischemic stroke. Changes of remote functional connectivity tend to interact with functional recovery. Future studies should estimate predictive values for individual patients and interactions with plasticity enhancing treatments

Cloning and expression of two proopiomelanocortin mRNAs in the common carp (Cyprinus carpio L.)

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Mangrove Archives: Unravelling Human-environment Interactions from Deeply Buried Deposits at the Site Anse Trabaud, Martinique, Lesser Antilles (1290-780 cal BP)

The site of Anse Trabaud on Martinique in the Windward Islands of the Lesser Antilles has yielded valuable information about human occupation from deep beneath its surface. The site is located in the southeastern part of the island, an area vulnerable to extreme wave events. The archaeological deposits are dated to 1290–780 cal BP (2σ). The earliest horizon is buried under thick layers of mangrove sediments. The deeply buried deposits have allowed excellent preservation of inorganic and organic remains providing an unexpected opportunity to reconstruct the paleoenvironmental conditions of past human settlement, and to study human-environment interactions and social adaptation to climate challenges in this part of the Caribbean archipelago. The cultural remains provide invaluable information into the exploitation of the surroundings of the site as well as into the subsistence patterns, material culture repertoires, procurement strategies and use and exchange of raw materials and tools. Additionally, the excellent preservation of organic materials offers new insights into food plants grown and harvested on-site, and then processed and consumed. The environmental challenges incited the Anse Trabaud community to adapt their settlement organisation and procurement strategies over time and underscore the importance of their participation in a regional and social network of mobility and exchange