A study on prevalence of metabolic syndrome in general population in Western Uttar Pradesh, India

Background: A global transition in the disease pattern has been observed, where the relative impact of infectious disease is decreasing while chronic disease like cardiovascular disease and diabetes are increasingly dominating the disease pattern. Metabolic syndrome (MetS) is a complex web of metabolic factors that are associated with a 2-fold increased risk of CVD and 5-fold risk of diabetes.Methods: A total of 350 patients were included and a cross sectional study was conducted to identify metabolic syndrome prevalence and to evaluate risk factor for development of metabolic syndrome.Results: 48% of participants were male and 52% were female our results showed a BMI of 22.11±3.57 in male and 22.16±2.82 in females. The overall prevalence of overweight was 31%. This study also showed significantly higher rate of metabolic syndrome in older age group i.e. 9.38% in age group of 30-39 years and 26.98% in 60-70 age group. Proportionally more subjects with MetS (74%) have sedentary life style as compared to those without MetS (54%).Conclusions: The prevalence of Metabolic syndrome varies among ethnic groups. Indians are at high risk for ASCVD and their predisposition. The high prevalence of overweight and obesity was one of the major driving force in the development of MetS

Rehabilitation of Maxillary defect using Removable Maxillary Cast Partial Denture Hollow Prosthesis for managing Mucomycosis patient: A Clinical Case Report

  Introduction: Mucormycosis is the fungal infection which especially affects immunocompromised patients. Case Report: In this case report, prosthetic rehabilitation of maxillary defect due to past mucormycosis in an uncontrolled diabetic patient was discussed by means of lightweight prosthesis by attaching a hollow occlusal shim to cast partial denture framework as absence of alveolar ridge on the defect side tends to increase the weight of the prosthesis which would have compromised the retention of the prosthesis. Conclusion: This technique is simple, economical and less time-consuming

The CMS Outer Hadron Calorimeter

The CMS hadron calorimeter is a sampling calorimeter with brass absorber and plastic scintillator tiles with wavelength shifting fibres for carrying the light to the readout device. The barrel hadron calorimeter is complemented with a outer calorimeter to ensure high energy shower containment in CMS and thus working as a tail catcher. Fabrication, testing and calibrations of the outer hadron calorimeter are carried out keeping in mind its importance in the energy measurement of jets in view of linearity and resolution. It will provide a net improvement in missing \et measurements at LHC energies. The outer hadron calorimeter has a very good signal to background ratio even for a minimum ionising particle and can hence be used in coincidence with the Resistive Plate Chambers of the CMS detector for the muon trigger

Restoration of lost connectivity of partitioned wireless sensor networks

The lost connectivity due to failure of large-scale nodes plays major role to degrade the system performance by generating unnecessary overhead or sometimes totally collapse the active network. There are many issues and challenges to restore the lost connectivity in an unattended scenario, i.e. how many recovery nodes will be sufficient and on which locations these recovery nodes have to be placed. A very few centralized and distributed approaches have been proposed till now. The centralized approaches are good for a scenario where information about the disjoint network, i.e. number of disjoint segments and their locations are well known in advance. However, for a scenario where such information is unknown due to the unattended harsh environment, a distributed approach is a better solution to restore the partitioned network. In this paper, we have proposed and implemented a semi-distributed approach called Relay node Placement using Fermat Point. The proposed approach is capable of restoring lost connectivity with small number of recovery relay nodes and it works for any number of disjoint segments. The simulation experiment results show effectiveness of our approach as compared to existing benchmark approaches

Biomedical waste management at tertiary level hospital–Rajindra Hospital [Government Medical College], Patiala-A situational analysis

Background: Studies in India and other developing countries has shown poor practice of Biomedical waste management [BMW]. Hence this study was undertaken to situation of BMW in our hospital, to identify the gaps and to take necessary steps for rectification. Materials & Methods: This was an observational descriptive hospital based cross sectional study. All sites where biomedical waste is generated, were visited during 3 months. The collection point was visited continuously for a week after collection of data from sites. The data, thus generated, were compiled, analyzed and inferences were drawn. Results: It showed that all Indoor site [100%] had a system for segregation and appropriate display as per guidelines was present. In OPDs the buckets were kept according to the waste type being generated i.e. not all colored buckets were kept. At 10% of sites the display was not to the standards desired. Among the remaining sites, 5 sites i.e. of sites the color coding guidelines were not followed. 37 such staff members recently assigned were found untrained. Conclusions: This study revealed that there is the need for the training programme and proper implementation of guidelines for BMW

Structural, microstructural and magnetic properties of NiFe2O4, CoFe2O4 and MnFe2O4 nanoferrite thin films

The structural, microstructural and magnetic properties of nanoferrite NiFe2O4 (NF), CoFe2O4 (CF) and MnFe2O4 (MF) thin films have been studied. The coating solution of these ferrite films was prepared by a chemical synthesis route called sol–gel combined metallo-organic decomposition method. The solution was coated on Si substrate by spin coating and annealed at 700 °C for 3 h. X-ray diffraction pattern has been used to analyze the phase structure and lattice parameters. The scanning electron microscopy (SEM) and atomic force microscopy (AFM) have been used to show the nanostructural behavior of these ferrites. The values of average grain's size from SEM are 44, 60 and 74 nm, and from AFM are 46, 61 and 75 nm, respectively, measured for NF, CF and MF ferrites. At room temperature, the values of saturation magnetization, Ms∼50.60, 33.52 and 5.40 emu/cc, and remanent magnetization, Mr∼14.33, 15.50 and 1.10 emu/cc, respectively, are observed for NF, CF and MF. At low temperature measurements of 10 K, the anisotropy of ferromagnetism is observed in these ferrite films. The superparamagnetic/paramagnetic behavior is also confirmed by χ′(T) curves of AC susceptibility by applying DC magnetizing field of 3 Oe. The temperature dependent magnetization measurements show the magnetic phase transition temperature

Dynamic assessments of hepatic encephalopathy and ammonia levels predict mortality in acute-on-chronic liver failure

Background: We evaluated the dynamics of hepatic encephalopathy (HE) and ammonia estimation in acute-on-chronic liver failure (ACLF) patients due to a paucity of evidence.Methods: ACLF patients recruited from the APASL-ACLF Research Consortium (AARC) were followed up till 30 days, death or transplantation, whichever earlier. Clinical details, including dynamic grades of HE and laboratory data, including ammonia levels, were serially noted.Results: Of the 3009 ACLF patients, 1315 (43.7%) had HE at presentation; grades I-II in 981 (74.6%) and grades III-IV in 334 (25.4%) patients. The independent predictors of HE at baseline were higher age, systemic inflammatory response, elevated ammonia levels, serum protein, sepsis and MELD score (p \u3c 0.05; each). The progressive course of HE was noted in 10.0% of patients without HE and 8.2% of patients with HE at baseline, respectively. Independent predictors of progressive course of HE were AARC score (≥ 9) and ammonia levels (≥ 85 μmol/L) (p \u3c 0.05; each) at baseline. A final grade of HE was achieved within 7 days in 70% of patients and those with final grades III-IV had the worst survival (8.9%). Ammonia levels were a significant predictor of HE occurrence, higher HE grades and 30-day mortality (p \u3c 0.05; each). The dynamic increase in the ammonia levels over 7 days could predict nonsurvivors and progression of HE (p \u3c 0.05; each). Ammonia, HE grade, SIRS, bilirubin, INR, creatinine, lactate and age were the independent predictors of 30-day mortality in ACLF patients.Conclusions: HE in ACLF is common and is associated with systemic inflammation, poor liver functions and high disease severity. Ammonia levels are associated with the presence, severity, progression of HE and mortality in ACLF patients