Six-month clinical outcomes of drug eluting stents in patients with coronary artery disease: an experience in real-world Indian patients

Background: Treatment of patients with coronary artery disease using drug eluting stents (DES) remains a challenge due to stent thrombosis and in-stent restenosis. The present study sought to investigate the safety and clinical performance of DES in real-world Indian patients with coronary artery disease.Methods: This prospective, non-randomized, single-center study enrolled 114 patients with coronary artery disease who were implanted with DES from January-2005 to September-2007. Clinical and angiographic follow-up were performed at 6 months after the index procedure. The primary endpoints of the study were: (major adverse cardiac events (MACE) defined as a composite of any episode of rest angina, myocardial infarctions (MI), repeat percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG), or (angiographic restenosis defined as ≥50% diameter stenosis at the treated site at 6-month follow-up. The secondary endpoints of the study were occurrence of any MACE events and stent vessel occlusion during the first 30 postprocedural days.Results: A total of 125 lesions were treated by implantation of 130 DES. Only one patient (0.9%) developed minor bleeding during hospitalization. At the 6-month follow-up, MACE was 10%, including 1 (1.3%) MI, 2 (2.5%) unstable angina, 3 (3.8%) stable angina, 1 (1.3%) repeat PCI, and 1 (1.3%) CABG. Angiographic restenosis was found in 7 (8.8%) patients. Comparison of characteristics between patients with and without angiographic restenosis revealed significant effects of presence of diabetes (p20 mm (p<0.05).Conclusions: The study results demonstrated excellent safety and clinical performance of DES in real-world Indian patients with coronary artery disease

DECONTAMINATION METHODS FOR TUBERCULOSIS: A REVIEW

Tuberculosis is a communicable disease spread from one person to another; it is caused by Mycobacterium tuberculosis. It’s a very dangerous bacterial infection liable for severe increase in death cases. It’s a chronic granulomatous infectious disease. Infection happens via aerosol and inhalation of some droplets containing mycobacteria bacilli. The disease also affects animals like cattle; this is often referred to as bovine tuberculosis, which can sometimes be communicated to man. The pulmonary tuberculosis is the most important type of tuberculosis which affects man. India is the highest Tuberculosis burden country within the world in terms of absolute number of incident cases that occur every year. It accounts for fourth part of the estimated global incident Tuberculosis cases in 2007

Decision Making with Operations Research in Global Business

The Operations Research is one of the employing technique used very much for make better decisions in the global business. Research has shown that majority of managers in global business organizations use of operations research techniques. The objective of this paper is to discuss the principles and ideas of Operations Research which are very helpful in a dynamic, complex and competitive business environment. To achieve the aim of the paper, this paper examines the nature of Operations Research, the Operations Research techniques available for managers and the various areas of operation where they can be applied. Therefore, this paper reviews the application of Operations Research to the Global business organizations to take the effective and consistent decision making to achieve business excellence

Right sided facial palsy more common in males while left sided facial palsy more common in females

Background: The study describes the retrospective analysis of 54 cases of facial nerve palsy patients seen in our neurophysiology Laboratory during February 2016 to January 2018.Methods: Clinically diagnosed cases of facial nerve palsy encountered at neurophysiology laboratory were analyzed on the basis of their diagnosis, age, sex, side affected and their seasonal occurrence. Patients were grouped in to four age groups of 60 yr.Results: Out of total 54 facial palsy cases with the mean age of 34.39±14.25 yr, 29 (53.70%) were males and 25 (46.30%) were females. Facial palsy was most common in 21-40 yr age group (42.59%, n=23), followed by 41-60 yr age group (29.63%, n=16). Nearly equal number of cases of right sided (26; 48.15%) and left sided (28; 51.85%) facial palsy were observe. However, right side facial palsy was more common in males with right side to left side facial palsy ratio of 1.90:1 and left sided facial palsy was more common in females with right side to left side facial palsy ratio of 1:2.57.Conclusions: Facial palsy cases are uniformly distributed among males and females with preponderance of right facial palsy in males and left facial palsy in females

Interference Aware Optimisation of Throughput in Cognitive Radio System

In the cognitive radio (CR) system where spectrum sensing and data transmissions are performed simultaneously, the proper selection of frame duration (τ) is of utmost importance. Small τ leads to an increased false alarm probability while large value of it delays implementation of sensing decision of the current frame to the next. The former case decreases the achievable throughput of the CR user while latter one may disturb the licensed user communication. Under the constraints of maintaining a target detection probability of dP, this paper attempts to design a frame duration τ where achieved throughput of the CR system is maximised. To do so, an analysis of achievable throughput with τ was performed which reveals that, initially, with the increase in τ, the achievable throughput increases sharply, but after its certain value, the increments are negligible and achievable throughput appears to maintain a constant value. The performed analysis shows that, it is not possible to perfectly optimize τ, however, a close optimisation can still be performed which can maximise the achievable throughput. From the realistic point of view, the CR system is further modelled under uncertain noise conditions. The achieved simulation results well justify the presented analysis.Defence Science Journal, Vol. 65, No. 4, July 2015, pp. 312-318, DOI: http://dx.doi.org/10.14429/dsj.65.873