A new concept in neurodegeneration: TNF alpha is a silencer of survival signals

International audienc

Growth hormone and insulin-like growth factor as cytokines in the immune system

3. ed. chap. 11 Mention d'édition : 3. ed.International audienc

[Retracted] A new mechanism of neurodegeneration : a proinflammatory cytokine inhibits receptor signaling by a survival peptide

The editors wish to note that Homer D. Venters submitted a letter to PNAS on December 1, 2008 that stated, “Based on findings by the Office of Research Integrity. See: https://doi.org/10.1073/pnas.0907385106International audienc

Tumor necrosis factor alpha and insulin-like growth factor-I in the brain : is the whole greater than the sum of its parts?

International audienc

IL-10 promotes survival of microglia without activating Akt

International audienc

At the interface of environment-immune interactions : cytokine and growth-factor receptors

International audienc

Diagnóstico laboratorial de raiva em quirópteros realizado em área metropolitana na região sudeste do Brasil Laboratory diagnosis of rabies in chiroptera carried out of a metropolitan area of Southeastern Brazil

No período de janeiro de 1988 adezembro de 1992, foi realizado diagnóstico de raiva em 289 morcegos através das técnicas de imunofluorescência direta e de inoculação intracerebral em camundongos. Dois morcegos insetívoros da espécie Nyctinomops macrotis se apresentaram positivos, representando 0,69% da amostra. Esses morcegos foram capturados, ainda vivos, em 1988 e 1990, na sala de um apartamento no sétimo andar e no muro de uma casa, respectivamente. Ambos em bairros residenciais. Apresentaram período de incubação de 13 e 11 dias, respectivamente, na prova biológica. A existência de morcegos insetívoros infectados com o vírus da raiva é preocupante, uma vez que essa população parece ser cada vez mais freqüente em áreas urbanas, porém isto não justifica ações predatórias indiscriminadas contra as espécies, principalmente levando-se em consideração a importância do morcego no equilíbrio ecológico da população de insetos, abundante em área urbana.<br>Between January, 1988 and December, 1992 the S. Paulo Animal Disease Control Center subjected 289 bats to rabies examinations, utilizing the direct immunofluorescence and biological techniques. Two insectivorous bats belonging to the species Nyctinomopsmacrotis, representing 0.69% of the total sample, tested positive. Both animals had been captured alive in residential neighborhoods of the city, one in 1988 in the living room of a 7' th floor apartment and the other in 1990 on top of a wall surrounding a private house. In the biological tests, the disease showed incubation periods of 13 and 11 days respectively.Although the existence of infected insectiverous bats in urban areas is cause for concern, indiscriminate predatory action against such species can in no way be justified-particularly bearing in mind their importance in preserving the ecological balance of the insect population so prevalent in cities