A new family of insecticides : the synthetic pyrethrinoïdes

Les auteurs présentent les structures et les propriétés physico chimiques des principaux pyréthrinoïdes de synthèse : la bioallethrine, la perméthrine, la cyperméthrine, le fenvalerate, la deltaméthrine et la fenpropathrine. Il est ensuite procédé à l’examen des applications phytosanitaires et vétérinaires et des problèmes de toxicité qui peu vent en découler chez l’homme en tant que consommateur et dans l’environnement.A NEW FAMILLY OF INSECTICIDS.' THE SYNTHETIC PYRETHRINOÏDES The authors give the structural and physico-chemical aspects of main pyrethrinoides: bioallethrin, permethrin, cypermethrin, fenva lerate, deltamethrin and fenpropathrin. Then, use in agriculture and veterinary therapy are examined with the toxicological effects for consumer and the environment

France’s proposal for Guidelines about setting Maximum Residue Limits in honey

contribution to session I Regulatory issues Background: Honey is produced in an environment potentially polluted by different sources of contamination, so it is necessary to set Maximum Residue Limits (MRLs). These MRLs should be fixed as low as possible in relation to Good Agricultural Practices (GAPs). The guidance provided in this Draft Working Document gives advice on: • when and for what kind of active substance a MRL has to be set in honey • how to propose a temporary MRL for a given active substance • how to design, prepare and realise supervised residue trials when necessary Results: The proposed approach is based on using the available data before an active substance or product is registered, and is divided into several successive steps, represented in a global decision-making scheme. The MRL will be set depending on the results obtained at each different step. Besides, the applicants will have the choice between different methods to set a provisional MRL in preregistration. Conclusion: The initial proposal was a protocol on field residue trials proposed by Germany. The approach used in this guidance document proposes also other possibilities for fixing MRL without conducting systematically field trials. This proposition will be discussed at European level. Keywords: Regulation 396/2005, MRL, honey, plant protection produc

Contamination of milk products with polychlorinated biphenyles

Les résidus de diphényles polychlorés (PCB) sont décelés pour la première fois dans les produits laitiers français en 1975. La contamination atteint 2,8 p. 100 des échantillons sur un total de 1 630. En 1976, une enquête plus particulièrement orientée sur les régions polluées, met en évidence un pourcentage de contamination plus élevé soit 28 p. 100 des échantillons sur un total de 1 012. La teneur résiduelle moyenne est de 4,03 ppm rapportée à la matière grasse en 1975, 1,70 ppm en 1976. Tous les problèmes de toxicologie à long terme relatifs aux PCB ou aux impuretés organo-chlorées qui les accompagnent, ne sont pas encore résolus. Des mesures de prévention ont été prises en France en 1975 (utilisation en circuit fermé).Polychlorinated Biphenyl residues are detected for the first time in French dairy products in 1975. In 1976, an investigation specially based on contaminated areas shows off a higher pollution (28 p. 100 of samples out of 1 012 in total). 4,03 ppm ( calculated on the fat) is the average residual amount in 1915 and 1,70 ppm in 1976. All the long term toxicologic problems of PCB or their chlorinated impurities are not yet resolved. In France, safety measures were taken in 1975 ( use only in closed circuit)

Adjuvants : regulatory aspects

International audienc