959 research outputs found

    Consumer acceptance of yellow, provitamin A-biofortified maize in KwaZulu-Natal

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    Objectives: To assess the acceptance of popular maize food products (phutu, thin porridge and samp), prepared with yellow, provitamin A-biofortified maize varieties, in 212 subjects between the ages of three and 55 years, from rural KwaZulu-Natal.Design: A cross-sectional study.Method: Preschool, primary school and secondary school subjects were randomly selected from two primary schools and one secondary school, respectively, while adult subjects constituted a convenience sample. Pre- and primary school children completed a paired preference test. Secondary school and adult subjects completed a five-point facial hedonic and a preference ranking test. Focus group discussions were conducted using adult subjects.Results: Preschool children preferred yellow maize to white maize food products: phutu (81% vs. 19%; p-value < 0.001), thin porridge (75% vs. 25%; p-value < 0.001) and samp (73% vs. 27%; p-value < 0.001). There was no statistically significant difference in preference for white and yellow maize by primary school children. Secondary school and adult subjects preferred white maize to yellow maize. Focus group discussions confirmed the preference for white maize by the adults.Conclusion: The study findings suggest that yellow, provitamin A-biofortified maize has the potential to succeed as a new strategy of dealing with the serious problem of vitamin A deficiency, especially among children of preschool age. However, in older groups, this strategy is unlikely to be successful, unless other strategies are implemented, including intensive nutrition education programmes on the nutritional benefits of the maize, targeting the market price at which yellow maize is sold, increasing its availability in local grocery stores, and improving its sensory properties through breeding.Keywords: yellow maize, provitamin A, vitamin A deficiency, consumer acceptanc

    Acceptance of a ready-to-use supplementary food by stable HIV-treated and HIV and tuberculosis (co-infected)-treated patients

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    Objectives: The objective of the study was to determine consumer  acceptance and perceptions of a ready-to-use supplementary food (RUSF)by subjects treated for human immunodeficiency virus (HIV) and HIV and tuberculosis (co-infected subjects).Design: A cross-sectional study was conducted.Subjects: One hundred and thirty-nine stable HIV-treated and HIV and tuberculosis (co-infected)-treated patients participated in the study. Sixty-eight healthy subjects served as the control group.Setting: The setting was Northdale Hospital and Grey’s Hospital in  Pietermaritzburg, KwaZulu-Natal.Outcome measures: Acceptance of the RUSF was assessed using a five-point facial hedonic scale by stable HIV-treated and HIV and tuberculosis (co-infected)-treated patients (n = 139) from Northdale Hospital and Grey’s Hospital in Pietermaritzburg, KwaZulu-Natal. Perceptions of the RUSF were determined through focus group discussions in which HIV-treated and HIV and tuberculosis (co-infected)-treated patients (n = 43) participated.Results: The overall acceptance of the RUSF was significantly associated with the health status of the subjects (p-value < 0.05). Overall, the product was liked by more than 90% of the HIV-treated and HIV and tuberculosis (co-infected)-treated individuals compared to 85% of the control group. More than 90% of the HIV-treated and HIV and tuberculosis   (co-infected)-treated individuals liked the taste, compared to 87% of the control group. The colour and mouth feel were rated to be “good” by more than 80% of the HIV-treated and HIV and tuberculosis (coinfected)-treated group, compared to approximately 70% of the healthy group. Focus group discussions revealed that the subjects perceived the mouth feel of the RUSF to be “rough”, and that as a health supplement, the RUSF should be provided free of charge, or at a reasonable cost, at public health centres.Conclusion: The RUSF was found to be highly acceptable to stable   HIV-treated and HIV and tuberculosis (co-infected)-treated subjects, although concern was raised about the mouth feel

    Emerging Synergisms Between Drugs and Physiologically-Patterned Weak Magnetic Fields: Implications for Neuropharmacology and the Human Population in the Twenty-First Century

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    Synergisms between pharmacological agents and endogenous neurotransmitters are familiar and frequent. The present review describes the experimental evidence for interactions between neuropharmacological compounds and the classes of weak magnetic fields that might be encountered in our daily environments. Whereas drugs mediate their effects through specific spatial (molecular) structures, magnetic fields mediate their effects through specific temporal patterns. Very weak (microT range) physiologically-patterned magnetic fields synergistically interact with drugs to strongly potentiate effects that have classically involved opiate, cholinergic, dopaminergic, serotonergic, and nitric oxide pathways. The combinations of the appropriately patterned magnetic fields and specific drugs can evoke changes that are several times larger than those evoked by the drugs alone. These novel synergisms provide a challenge for a future within an electromagnetic, technological world. They may also reveal fundamental, common physical mechanisms by which magnetic fields and chemical reactions affect the organism from the level of fundamental particles to the entire living system

    Eulerian modeling of inertial and diffusional aerosol deposition in bent pipes

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    This paper presents a sectional Eulerian aerosol model for size-dependent droplet deposition at walls of the domain, driven by both diffusion and inertia. The model is based on the internally mixed assumption and employs the formulation for compressible aerosols. It is validated in a bent pipe geometry against models and experimental and numerical data from literature. Good agreement is found in both the diffusion and inertial deposition regimes. To improve the overprediction of inertial deposition by a boundary treatment that adopts zero-gradient droplet wall velocity, we use a corrected wall velocity, based on an analytical solution of the droplet motion near the wall. In the bent pipe setting the corrected wall velocity is found to reduce the overprediction of deposition and is less sensitive to grid refinement. We also show that refining the computational mesh near the pipe wall improves the predicted deposition efficiency, significantly. Finally, we present a parameter study varying the Reynolds number and the bend curvature. The deposition efficiency curve is recorded for droplet diameters ranging from the nanometer scale to beyond the micrometer scale, which is a unique contribution of this paper. The complete size range is simulated in only one simulation, due to the sectional approach. In the diffusion-dominated regime an increase in Reynolds number leads to a gradual enhancement of deposition. In the inertial regime, where droplet drift dominates deposition, a much stronger dependence on the Reynolds number is found. The dependence of the deposition on the bend curvature is less pronounced. The results shown in this paper establish the role of Eulerian simulation in predicting deposition of aerosol droplets and are useful for understanding size-dependent aerosol deposition in other more complex confined geometries

    Branching of the Falkner-Skan solutions for λ < 0

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    The Falkner-Skan equation f'" + ff" + λ(1 - f'^2) = 0, f(0) = f'(0) = 0, is discussed for λ < 0. Two types of problems, one with f'(∞) = 1 and another with f'(∞) = -1, are considered. For λ = 0- a close relation between these two types is found. For λ < -1 both types of problem allow multiple solutions which may be distinguished by an integer N denoting the number of zeros of f' - 1. The numerical results indicate that the solution branches with f'(∞) = 1 and those with f'(∞) = -1 tend towards a common limit curve as N increases indefinitely. Finally a periodic solution, existing for λ < -1, is presented.
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