Alternatives for reductionist approaches to comparative Bantu grammar

Studies on most domains of comparative Bantu grammar are typically confronted with a huge amount of data and complex, interacting dimensions of variation. They tend to involve an initial methodological step of reducing this variation by classifying constructions, grammatical properties or entire languages into a finite set of types. This paper argues against such reductionist approaches to linguistic evidence and illustrates several methodological alternatives, one of which is here introduced as the scenario-based approach. I will argue that these alternative approaches are at least as good in managing data and finding generalisations as the reductionist approach, but that they give more reliable results and are better at discovering variation.Les études portant sur la plupart des domaines de la grammaire bantoue comparée sont généralement confrontées à une énorme quantité de données et à des dimensions de variation complexes et interactives. Elles tendent à induire une étape méthodologique initiale de réduction de cette variation en classant les constructions, les propriétés grammaticales ou les langues entières dans un ensemble fini de types. Cet article s'oppose à ces approches réductionnistes des données linguistiques et illustre plusieurs alternatives méthodologiques, dont l'une est présentée ici comme l'approche basée sur des scénarios. Je soutiens que ces approches alternatives sont au moins aussi efficaces pour gérer les données et trouver des généralisations que l'approche réductionniste, mais qu'elles donnent des résultats plus fiables et permettent de mieux mettre en lumière la variation

Acute-phase response patterns in isolated hepatic perfusion with tumour necrosis factor α (TNF-α) and melphalan in patients with colorectal liver metastases

Background. In this study, we have evaluated hepatotoxicity, secondary cytokine production and hepatic acute-phase response (APR) in patients who underwent isolated hepatic perfusion (IHP) with tumour necrosis factor (TNF) α and melphalan for irresectable colorectal liver metastases. Design. An extracorporeal veno-venous bypass was used to shunt blood from the lower body and intestines to the heart. Inflow catheters were placed in the hepatic artery and portal vein, and an outflow catheter in the inferior caval vein. The liver was perfused for 60 min with 0.4 mg of TNF-α plus 1 mg kg-1 melphalan (IHP(TM) group, n = 6) or 1 mg kg-1 melphalan (IHP(M) group, n = 3). The liver was washed with macrodex before restoring vascular continuity. Results. After the washout procedure, a TNF-α peak (169 ± 38 pg mL-1) was demons

SORTA:a system for ontology-based re-coding and technical annotation of biomedical phenotype data

There is an urgent need to standardize the semantics of biomedical data values, such as phenotypes, to enable comparative and integrative analyses. However, it is unlikely that all studies will use the same data collection protocols. As a result, retrospective standardization is often required, which involves matching of original (unstructured or locally coded) data to widely used coding or ontology systems such as SNOMED CT (clinical terms), ICD-10 (International Classification of Disease) and HPO (Human Phenotype Ontology). This data curation process is usually a time-consuming process performed by a human expert. To help mechanize this process, we have developed SORTA, a computer-aided system for rapidly encoding free text or locally coded values to a formal coding system or ontology. SORTA matches original data values (uploaded in semicolon delimited format) to a target coding system (uploaded in Excel spreadsheet, OWL ontology web language or OBO open biomedical ontologies format). It then semi-automatically shortlists candidate codes for each data value using Lucene and n-gram based matching algorithms, and can also learn from matches chosen by human experts. We evaluated SORTA's applicability in two use cases. For the LifeLines biobank, we used SORTA to recode 90 000 free text values (including 5211 unique values) about physical exercise to MET (Metabolic Equivalent of Task) codes. For the CINEAS clinical symptom coding system, we used SORTA to map to HPO, enriching HPO when necessary (315 terms matched so far). Out of the shortlists at rank 1, we found a precision/recall of 0.97/0.98 in LifeLines and of 0.58/0.45 in CINEAS. More importantly, users found the tool both a major time saver and a quality improvement because SORTA reduced the chances of human mistakes. Thus, SORTA can dramatically ease data (re) coding tasks and we believe it will prove useful for many more projects

Fiscal Centralization, Limited Government, and Public Revenues in Europe, 1650-1913

Old Regime polities typically suffered from fiscal fragmentation and absolutist rule. By the start of World War I, however, many such countries had centralized institutions and limited government. This article uses a new panel data set to perform a statistical analysis of political regimes and public revenues in Europe from 1650 to 1913. Panel regressions indicate that centralized and limited regimes were associated with significantly higher revenues than fragmented and absolutist ones. Structural break tests also suggest close relationships between major turning points in revenue series and political transformations

Innovative technologies for under-resourced language documentation: The BULB Project

International audienceThe project Breaking the Unwritten Language Barrier (BULB), which brings together linguists and computer scientists, aims at supporting linguists in documenting unwritten languages. In order to achieve this we will develop tools tailored to the needs of documentary linguists by building upon technology and expertise from the area of natural language processing, most prominently automatic speech recognition and machine translation. As a development and test bed for this we have chosen three less-resourced African languages from the Bantu family: Basaa, Myene and Embosi. Work within the project is divided into three main steps: 1) Collection of a large corpus of speech (100h per language) at a reasonable cost. After initial recording, the data is re-spoken by a reference speaker to enhance the signal quality and orally translated into French. 2) Automatic transcription of the Bantu languages at phoneme level and the French translation at word level. The recognized Bantu phonemes and French words will then be automatically aligned. 3) Tool development. In close cooperation and discussion with the linguists, the speech and language technologists will design and implement tools that will support the linguists in their work, taking into account the linguists' needs and technology's capabilities. The data collection has begun for the three languages. For this we use standard mobile devices and a dedicated software—LIG-AIKUMA, which proposes a range of different speech collection modes (recording, respeaking, translation and elicitation). LIG-AIKUMA 's improved features include a smart generation and handling of speaker metadata as well as respeaking and parallel audio data mapping

Innovative technologies for under-resourced language documentation: The BULB Project

International audienceThe project Breaking the Unwritten Language Barrier (BULB), which brings together linguists and computer scientists, aims at supporting linguists in documenting unwritten languages. In order to achieve this we will develop tools tailored to the needs of documentary linguists by building upon technology and expertise from the area of natural language processing, most prominently automatic speech recognition and machine translation. As a development and test bed for this we have chosen three less-resourced African languages from the Bantu family: Basaa, Myene and Embosi. Work within the project is divided into three main steps: 1) Collection of a large corpus of speech (100h per language) at a reasonable cost. After initial recording, the data is re-spoken by a reference speaker to enhance the signal quality and orally translated into French. 2) Automatic transcription of the Bantu languages at phoneme level and the French translation at word level. The recognized Bantu phonemes and French words will then be automatically aligned. 3) Tool development. In close cooperation and discussion with the linguists, the speech and language technologists will design and implement tools that will support the linguists in their work, taking into account the linguists' needs and technology's capabilities. The data collection has begun for the three languages. For this we use standard mobile devices and a dedicated software—LIG-AIKUMA, which proposes a range of different speech collection modes (recording, respeaking, translation and elicitation). LIG-AIKUMA 's improved features include a smart generation and handling of speaker metadata as well as respeaking and parallel audio data mapping

Level of arterial ligation in total mesorectal excision (TME): an anatomical study

Introduction: High-tie ligation is a common practice in rectal cancer surgery. However, it compromises perfusion of the proximal limb of the anastomosis. This anatomical study was designed to assess the value of low-tie ligation in order to obtain a tension-free anastomosis. Materials and methods: Consecutive high- and low-tie resections were performed on 15 formalin-fixed specimens, with or without splenic flexure mobilization. If the proximal colon limb could reach the superior aspect of the symphysis pubis with more than 3 cm, the limb would be long enough for a tension-free colorectal anastomosis. Results: In 80% of cases, it was not necessary to perform high-tie ligation as sufficient length was gained with low-tie ligation. The descending branch of the left colic artery was the limiting factor in the other 20% of cases. Resecting half the sigmoid resulted in four times as many tension-free anastomoses after low-tie resection. Conclusion: In the majority of cases, it was not necessary to perform high-tie ligation in order to create a tension-free anastomosis. Low-tie ligation was applicable in 80% of cases and might prevent anastomotic leakage due to insufficient blood supply of the proximal colon limb

Political Regimes and Sovereign Credit Risk in Europe, 1750-1913

This article uses a new panel data set to perform a statistical analysis of political regimes and sovereign credit risk in Europe from 1750 to 1913. Old Regime polities typically suffered from fiscal fragmentation and absolutist rule. By the start of World War I, however, many such countries had centralized institutions and limited government. Panel regressions indicate that centralized and?or limited regimes were associated with significant improvements in credit risk relative to fragmented and absolutist ones. Structural break tests also reveal close relationships between major turning points in yield series and political transformations