14 research outputs found
La normalització de documents administratius al Departament de Cultura: un projecte interdisciplinari
Working memory performance, pain and associated clinical variables in women with fibromyalgia
Working memory (WM) is a critical process for cognitive functioning in which fibromyalgia
(FM) patients could show cognitive disturbances. Dyscognition in FM has been
explained by interference from pain processing, which shares the neural substrates
involved in cognition and may capture neural resources required to perform cognitive
tasks. However, there is not yet data about how pain is related to WM performance,
neither the role that other clinical variables could have. The objectives of this study were
(1) to clarify the WM status of patients with FM and its relationship with nociception,
and (2) to determine the clinical variables associated to FM that best predict WM
performance. To this end, 132 women with FM undertook a neuropsychological
assessment of WM functioning (Digit span, Spatial span, ACT tests and a 2-Back
task) and a complete clinical assessment (FSQ, FIQ-R, BDI-1A, HADS, PSQI, MFE-30
questionnaires), including determination of pain thresholds and tolerance by pressure
algometry. Patients with FM seem to preserve their WM span and ability to maintain and
manipulate information online for both visuospatial and verbal domains. However, up
to one-third of patients showed impairment in tasks requiring more short-term memory
load, divided attention, and information processing ability (measured by the ACT task).
Cognitive performance was spuriously related to the level of pain experienced, finding
only that pain measures are related to the ACT task. The results of the linear regression
analyses suggest that sleep problems and fatigue were the variables that best predicted
WM performance in FM patients. Future research should take these variables into
account when evaluating dyscognition in FM and should include dynamic measures
of pain modulationThis study was funded by the Spanish State Research Agency (Call: Retos 2016. Project reference: PSI2016-75313-R) and Consellería de Cultura, Educación e Universidades, Xunta de Galicia (Code: ED431C 2021/04)S