Rapture of renal angiomyolipoma during pregnancy: a case report

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Study of the effect of nocturia in males with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (lower urinary tract symptoms due to benign prostatic hyperplasia – LUTS/BPH)

Objectives: To examine how much does nocturia affect quality of life in patients with LUTS/BPH and also to compare the effect of administration of tamsulosin 0.4mg per os daily and transurethral prostatectomy in the treatment of nocturia in previously untreated men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia and no other predisposing factor for nocturia. Methods: The study group included 66 patients (mean age 68.9 years) randomized to receive either tamsulosin 0.4 mg once daily or transurethral prostatectomy (TURP) in order to treat refractory lower urinary tract symptoms. Nocturia severity was assessed initially and after three months and one year by the number of nocturnal awakenings and hours of undisturbed sleep (HUS) obtained from a 72 hours Frequency Volume Chart (FVC), scores of international prostate symptom score (IPSS), international consultation on incontinence questionnaire nocturia (ICIQ-N), international consultation on incontinence questionnaire nocturia quality of life (ICIQ-NQol). Results: At baseline, the number of awakenings and HUS were correlated with ICIQ-NQol and ICIQ-N scores. Both administration of tamsulosin and transurethral prostatectomy improved all examined parameters with time. When the improvement is compared between the two groups, transurethral prostatectomy is associated with improvement in the number of nocturnal awakenings and also in the IPSS, ICIQ-N and ICIQ-NQol scores. Hours of undisturbed sleep increase in both groups but no significant interaction between the two groups was demonstrated. Conclusions: Nocturia affects negatively the quality of life in patients with LUTS/BPH. TURP appears to be superior to tamsulosin when the number of nocturnal awakenings is examined while no significant differences were observed between the two therapeutic approaches regarding the hours of undisturbed sleep.Σκοπός: Να εξετάσουμε αν η νυκτουρία επηρεάζει την ποιότητα ζωής των ασθενών με LUTS/BPH και να συγκρίνουμε το θεραπευτικό αποτέλεσμα της χορήγησης ταμσουλοσίνης 0.4mg per os ημερησίως και της διουρηθρικής προστατεκτομής στην θεραπεία της νυκτουρίας σε άρρενες με συμπτώματα από το κατώτερο ουροποιητικό σύστημα οφειλόμενα στην καλοήθη υπερπλασία του προστάτη αδένα οι οποίοι δεν είχαν λάβει θεραπεία στο παρελθόν και δεν εμφάνιζαν λοιπούς προδιαθεσικούς παράγοντες για την εμφάνιση νυκτουρίας. Υλικό και μέθοδοι: Εξηνταέξι (μ.ο. ηλικίας 68.9 έτη) άρρενες τυχαιοποιήθηκαν ώστε να λάβουν ταμσουλοσίνη 0.4mg per os ημερησίως ή να υποβληθούν σε διουρηθρική προστατεκτομή. Η νυκτουρία εξετάστηκε κατά τον αρχικό έλεγχο, τρεις μήνες και ένα χρόνο μετά μέσω των αφυπνίσεων και των ωρών του ανεμπόδιστου ύπνου από την καταγραφή ημερολογίου ούρησης διάρκειας 72 ωρών και τα σκορ των ερωτηματολογίων IPSS, ICIQ-N και ICIQ-NQol. Αποτελέσματα: Κατά τον αρχικό έλεγχο, ο αριθμός των νυκτερινών αφυπνίσεων και των ωρών του ανεμπόδιστου ύπνου σχετίζονταν με τα σκορ ICIQ-N και ICIQ-NQol. Τόσο η ταμσουλοσίνη όσο και η διουρηθρική προαστατεκτομή βελτίωσαν τις υπό εξέταση παράμετρους. Όταν συγκρίθηκαν τα δυο γκρουπ, η διουρηθρική προστατεκτομή σχετίστηκε με βελτίωση στον αριθμό των νυκτερινών αφυπνίσεων και των σκορ IPSS, ICIQ-N και ICIQ-NQol. Οι ώρες του ανεμπόδιστου ύπνου αυξάνονται και στα δύο γκρουπ χωρίς σημαντική διαφορά. Συμπεράσματα: H νυκτουρία επηρεάζει αρνητικά την ποιότητα ζωής των ασθενών με LUTS/BPH. H διουρηθρική προστατεκτομή φαίνεται να είναι αποτελεσματικότερη της ταμσουλοσίνης όσον αφορά στη μείωση των νυκτερινών αφυπνίσεων ενώ δεν παρατηρήθκαν σημαντικές διαφορές μεταξύ των δυο γκρουπ στις ώρες του ανεμπόδιστου ύπνου

Tamsulosin versus transurethral resection of the prostate: Effect on nocturia as a result of benign prostatic hyperplasia

Our objective was to compare the effect of tamsulosin versus transurethral resection of the prostate (TURP) for the management of nocturia in previously untreated men with lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH) and no other predisposing factors for nocturia. The study group included 66 patients (mean age 68.9 years, range 52-81) randomized to receive either tamsulosin 0.4 mg per os daily (n = 33) or TURP (n = 33). Nocturia was assessed at baseline, after 3 months and after 1 year, by the number of nocturnal awakenings and hours of undisturbed sleep (HUS) obtained from a 72-h Frequency Volume Chart (FVC). Furthermore, the International Prostate Symptom Score (IPSS), the International Consultation on Incontinence Questionnaire Nocturia (ICIQ-N) and the International Consultation on Incontinence Questionnaire Nocturia Quality of Life (ICIQ-NQoL) were recorded. At baseline, there were no statistically significant differences between the two groups. ICIQNQoL and ICIQ-N scores correlated with the number of awakenings and HUS, respectively. Both tamsulosin and TURP improved all examined parameters during the follow up. TURP was associated with a statistically significant improvement in the number of nocturnal awakenings and in the IPSS, ICIQ-N and ICIQ-NQol scores in comparison with tamsulosin. HUS increased in both groups, but without any statistically significant difference. In conclusion, TURP is superior in comparison with tamsulosin for the management of BPH-related nocturia

Burned-out testicular tumor with retroperitoneal lymph node metastasis: a case report

Abstract Introduction A burned-out seminoma of the testis is an exceptionally rare clinical entity, with few reports found in the literature. Case presentation A case of burned-out tumor of the testis in a 31-year-old man is reported. The tumor presented as a retroperitoneal mass with histological characteristic of a seminoma. The testes on clinical examination were normal, and a suspicious lesion in the scrotum was only identified after ultrasound. Incision of the abdominal mass was decided, followed by orchectomy. Histological examination of the testis revealed a suspicious lesion with characteristics of spontaneous regression of germ cell tumors. Conclusion We describe one of very few cases worldwide, where spontaneous regression of a primary testicular tumor occurred after demonstration of retroperitoneal lymph node metastasis, a phenomenon known as burned-out seminoma, which is hard to recognize and incompletely characterized by physicians.</p