16 research outputs found
Avaliação da insuficiência da veia safena magna com classificação C2 e C3 (CEAP) pela pletismografia a ar e pelo eco-Doppler colorido
Assessment of voice quality after carotid endarterectomy
Objectives: vocal cord paralysis is considered a rare complication of
carotid endarterectomy (CEA), but alteration in voice quality may be
more common. The aim of this prospective study was to evaluate the
effect of CEA on voice quality and to correlate any changes with the
extent of the dissection.
Design - Material - Methods: thirty-five patients who underwent CEA were
divided in two groups, according to the level of surgical dissection
performed. The high-level dissection group was comprised of those
patients that required mobilisation of hypoglossal nerve and division of
the posterior belly of digastric muscle. The low-level dissection group
included the rest. All the patients’ voices were recorded and analysed
digitally before CEA, one and three months after the operation. Voice
data were measured for standard deviation of fundamental frequency,
jitter, shimmer and normalised noise energy (NNE). All patients
underwent a laryngeal examination pre- and post-operation.
Results: none of the patients had any vocal cord dysfunction on
laryngoscopy. Significant changes of voice quality (jitter, shimmer,
NNE) were noticed in the high-level dissection group (p < 0.05) one
month after the operation: Two months later, the voice changes had
subsided, but still significant disturbances remained (jitter, shimmer).
Conclusions: voice-related disturbances are far more common following
CEA than is generally believed and, although they seem to for the most
part temporary, they deserve attention. Specifically, high-level
surgical dissection seems to be a risk factor of postoperative vocal
impairment
A randomized, single-blinded cross-over trial of ischemic preconditioning in Raynaud's phenomenon
Preoperative imaging in primary and recurrent varicosis: Venography or color coded duplex sonography
Avaliação do refluxo venoso superficial ao mapeamento dúplex em portadores de varizes primárias de membros inferiores: correlação com a gravidade clínica da classificação CEAP
Protective role of heparin in the injury of the liver and kidney on the experimental model of ischemia/reperfusion
PubMed ID: 24533613Background: Surgery of thoracoabdominal aortic aneurysms (TAAA) is associated with high incidence of serious complications. Ischemia/reperfusion (I/R) injury may be responsible for these complications. We investigated the effect of degree of anticoagulation on remote organ I/R injuries and whether heparin is protective against I/R injury in addition to its anticoagulant properties.Methods: Spraque Dawley rats were used to determine both liver and kidney concentrations of HSP-70,IL-6, MPO in four groups: ischemic control (operation with cross-clamping and intraperitoneal administration of 0.9% saline, n = 7), sham (operation without cross-clamping, n = 7), heparin (ACT level about 200), and high dose heparin (ACT level up to 600). Histological analyses of the organs were performed.Results: Histopathological evaluation of kidney presented significant differences between groups with regards to the cytoplasmic vacuole formation, hemorrhage, tubular cell degeneration and tubular dilatation while heparinized group had best results. The kidney MPO and HSP-70 levels significantly decreased (p 0.05) in heparinized group when compared to ischemic control group. No statistically significant intergroup differences were detected in the tissue samples of liver. Immunohistochemical markers of the liver were compared and no statistically significant difference was found among the groups.Conclusion: Heparin is an important anticoagulation agent in TAAA surgical procedures but the use of higher levels of heparin in the present study revealed no beneficial effects. Bleeding complications is much less when heparin is used in the real-world clinical practice as ACT levels of 200. © 2014 Yener et al.; licensee BioMed Central Ltd