Towards robust aero-thermodynamic predictions for re-usable single-stage to orbit vehicles

Re-usable single stage to orbit launch vehicles promise to reduce the cost of access to space, but their success will be particularly reliant on accurate and robust modelling of their aero-thermodynamic characteristics. For preliminary design and optimization studies, relatively simple numerical prediction techniques must perforce be used, but it is important that the uncertainty that is inherent in the predictions of these models be understood. Predictions of surface pressure and heat transfer obtained using a new reduced-order model that is based on the Newtonian flow assumption and the Reynolds analogy for heating are compared against those of a more physically-sophisticated Direct Simulation Monte Carlo method in order to determine the ability of the model to capture the aero-thermodynamics of vehicles with very complex configuration even when run at low enough resolution to be practical in the context of design optimization studies. Attention is focused on the high-altitude regime where lifting re-usable Single-Stage to Orbit configurations will experience their greatest thermal load during re-entry, but where non-continuum effects within the gas of the atmosphere might be important. It is shown that the reduced-order model is capable of reproducing the results of the more complex Monte Carlo formalism with surprising fidelity, but that residual uncertainties exist, particularly in the behaviour of the heating models and in the applicability of the continuum assumption given the onset of finite slip velocity on surface of vehicle. The results suggest thus that, if used with care, reduced-order models such as those described here can be used very effectively in the design and optimization of space-access vehicles with very complex configuration, as long as their predictions are adequately supported by the use of more sophisticated computational techniques

The Scimitar Precooled Mach 5 Engine

Accepted versio

Numerical Analysis of the SKYLON Spaceplane in Hypersonic Flow

The paper investigates selected hypersonic flow conditions along the SKYLON re-entry trajectory based on Navier-Stokes simulations with the DLR TAU code. The obtained surface values are compared in order to find the most critical flow condition with respect to the maximum heat flux and the surface temperatures

Pre-cooler Design and Development

status: publishe

Hypersonic Passenger Transport Vehicles: Major achievements realized within the LAPCAT-II project

status: publishe

A gene involved in XY sex reversal is located on chromosome 9, distal to marker D9S1779.

The genetic mechanisms involved in sex differentiation are poorly understood, and progress in identification of the genes involved has been slow. The fortuitous finding of chromosomal rearrangements in association with a sex-reversed phenotype has led to the isolation of SRY and SOX9, both shown to be involved in the sex-determining pathway. In addition, duplications of the X chromosome, deletions of chromosomes 9 and 10, and translocations involving chromosome 17 have been reported to be associated with abnormal testicular differentiation, leading to male-to-female sex reversal in 46,XY individuals. We present the cytogenetic and molecular analyses of four sex-reversed XY females, each with gonadal dysgenesis and other variable malformations, and with terminal deletions of distal chromosome 9p, resulting from unbalanced autosomal translocations. PCR amplification and DNA sequence analysis of SRY revealed no mutations in the high-mobility-group domain (i.e., HMG box) in any of the four patients. Conventional and molecular cytogenetic analyses of metaphase chromosomes from each patient suggest that the smallest region of overlap (SRO) of deletions involves a very small region of distal band 9p24. Loss-of-heterozygosity studies using 17 highly polymorphic microsatellite markers, as well as FISH using YAC clones corresponding to the most distal markers on 9p, showed that the SRO lies distal to marker D9S1779. These results significantly narrow the putative sex-determining gene to the very terminal region of the short arm of chromosome 9